Limits...
Effects of a buried magnetic field on cranial bone reconstruction in rats.

Abreu MC, Ponzoni D, Langie R, Artuzi FE, Puricelli E - J Appl Oral Sci (2016)

Bottom Line: Results These analyses showed significant group by postoperative time interactions (p=0.008).Results also showed that the quality of bone repair remained higher in the former group as compared to the latter at 60 postoperative days.Conclusions After 60 postoperative days, bone repair was greater in the group treated with autogenous bone grafts and exposed to a magnetic field, and bone repair was most pronounced in animals treated with autogenous bone grafts, followed by those treated with powdered synthetic hydroxyapatite and allogeneic cartilage grafts.

View Article: PubMed Central - PubMed

Affiliation: Departamento de Cirurgia Oral e Maxilofacial, Faculdade de Odontologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.

ABSTRACT
The understanding of bone repair phenomena is a fundamental part of dentistry and maxillofacial surgery. Objective The present study aimed to evaluate the influence of buried magnetic field stimulation on bone repair in rat calvaria after reconstruction with autogenous bone grafts, synthetic powdered hydroxyapatite, or allogeneic cartilage grafts, with or without exposure to magnetic stimulation. Material and Methods Ninety male Wistar rats were divided into 18 groups of five animals each. Critical bone defects were created in the rats' calvaria and immediately reconstructed with autogenous bone, powdered synthetic hydroxyapatite or allogeneic cartilage. Magnetic implants were also placed in half the animals. Rats were euthanized for analysis at 15, 30, and 60 postoperative days. Histomorphometric analyses of the quantity of bone repair were performed at all times. Results These analyses showed significant group by postoperative time interactions (p=0.008). Among the rats subjected to autogenous bone reconstruction, those exposed to magnetic stimulation had higher bone fill percentages than those without magnetic implants. Results also showed that the quality of bone repair remained higher in the former group as compared to the latter at 60 postoperative days. Conclusions After 60 postoperative days, bone repair was greater in the group treated with autogenous bone grafts and exposed to a magnetic field, and bone repair was most pronounced in animals treated with autogenous bone grafts, followed by those treated with powdered synthetic hydroxyapatite and allogeneic cartilage grafts.

No MeSH data available.


Related in: MedlinePlus

Graphical representation of the percentage of bone formation over time for all groups at 15 postoperative days: AB+M > CT (*); At 30 postoperative days: AB+M > CT (#); At 60 postoperative days: HA+M > CT (+); At 60 postoperative days: AB+M > CT e AB (**). Different capital letters show longitudinal differences
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4836924&req=5

f04: Graphical representation of the percentage of bone formation over time for all groups at 15 postoperative days: AB+M > CT (*); At 30 postoperative days: AB+M > CT (#); At 60 postoperative days: HA+M > CT (+); At 60 postoperative days: AB+M > CT e AB (**). Different capital letters show longitudinal differences

Mentions: Longitudinal analyses were also performed to evaluate the development of each group over time. In the allogeneic cartilage graft with magnetic field (CT+M), hydroxyapatite implant without magnetic field (HA), AB, and AB+M groups, bone fill percentage after 15 days was lower than that found after 30 and 60 days. In HA+M rats, differences were only observed after 60 days, at which point bone fill percentages were significantly higher than those observed after 15 and 30 days. In the CT group, although differences in bone fill were observed between 15 and 60 days, bone fill at 30 postoperative days did not differ from that found after 15 and 60 days - represented in the graph by different capital letters. The graphical representation of the percentage of bone fill shows the between-group and longitudinal comparisons (Figure 4).


Effects of a buried magnetic field on cranial bone reconstruction in rats.

Abreu MC, Ponzoni D, Langie R, Artuzi FE, Puricelli E - J Appl Oral Sci (2016)

Graphical representation of the percentage of bone formation over time for all groups at 15 postoperative days: AB+M > CT (*); At 30 postoperative days: AB+M > CT (#); At 60 postoperative days: HA+M > CT (+); At 60 postoperative days: AB+M > CT e AB (**). Different capital letters show longitudinal differences
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4836924&req=5

f04: Graphical representation of the percentage of bone formation over time for all groups at 15 postoperative days: AB+M > CT (*); At 30 postoperative days: AB+M > CT (#); At 60 postoperative days: HA+M > CT (+); At 60 postoperative days: AB+M > CT e AB (**). Different capital letters show longitudinal differences
Mentions: Longitudinal analyses were also performed to evaluate the development of each group over time. In the allogeneic cartilage graft with magnetic field (CT+M), hydroxyapatite implant without magnetic field (HA), AB, and AB+M groups, bone fill percentage after 15 days was lower than that found after 30 and 60 days. In HA+M rats, differences were only observed after 60 days, at which point bone fill percentages were significantly higher than those observed after 15 and 30 days. In the CT group, although differences in bone fill were observed between 15 and 60 days, bone fill at 30 postoperative days did not differ from that found after 15 and 60 days - represented in the graph by different capital letters. The graphical representation of the percentage of bone fill shows the between-group and longitudinal comparisons (Figure 4).

Bottom Line: Results These analyses showed significant group by postoperative time interactions (p=0.008).Results also showed that the quality of bone repair remained higher in the former group as compared to the latter at 60 postoperative days.Conclusions After 60 postoperative days, bone repair was greater in the group treated with autogenous bone grafts and exposed to a magnetic field, and bone repair was most pronounced in animals treated with autogenous bone grafts, followed by those treated with powdered synthetic hydroxyapatite and allogeneic cartilage grafts.

View Article: PubMed Central - PubMed

Affiliation: Departamento de Cirurgia Oral e Maxilofacial, Faculdade de Odontologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.

ABSTRACT
The understanding of bone repair phenomena is a fundamental part of dentistry and maxillofacial surgery. Objective The present study aimed to evaluate the influence of buried magnetic field stimulation on bone repair in rat calvaria after reconstruction with autogenous bone grafts, synthetic powdered hydroxyapatite, or allogeneic cartilage grafts, with or without exposure to magnetic stimulation. Material and Methods Ninety male Wistar rats were divided into 18 groups of five animals each. Critical bone defects were created in the rats' calvaria and immediately reconstructed with autogenous bone, powdered synthetic hydroxyapatite or allogeneic cartilage. Magnetic implants were also placed in half the animals. Rats were euthanized for analysis at 15, 30, and 60 postoperative days. Histomorphometric analyses of the quantity of bone repair were performed at all times. Results These analyses showed significant group by postoperative time interactions (p=0.008). Among the rats subjected to autogenous bone reconstruction, those exposed to magnetic stimulation had higher bone fill percentages than those without magnetic implants. Results also showed that the quality of bone repair remained higher in the former group as compared to the latter at 60 postoperative days. Conclusions After 60 postoperative days, bone repair was greater in the group treated with autogenous bone grafts and exposed to a magnetic field, and bone repair was most pronounced in animals treated with autogenous bone grafts, followed by those treated with powdered synthetic hydroxyapatite and allogeneic cartilage grafts.

No MeSH data available.


Related in: MedlinePlus