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Screening for Chronic Obstructive Pulmonary Disease in Smoking Cessation Clinic in France.

Richard P, Gilles H, Alavi Z, Christine L, Maryline le B, Ronan G, Laurence P, Jean P, Jean-Dominique D - Addict Health (2016)

Bottom Line: This study was based on a multicenter survey with questionnaires (Richmond, Fagerstrom, clinical signs) and spirometry miniaturized.Data were analyzed with SAS® by Pearson chi-square test, the test of analysis of variance, Spearman correlation coefficient, and multivariate logistic regression step down. 1918 patients were assessed for eligibility and only 1737 were included.The report forced expiratory volume in 1 second (FEV1/FEV6) was < 0.8 for 33.2% of smokers and < 0.7 for 7.5% of them.

View Article: PubMed Central - PubMed

Affiliation: Tobaccology Center, University Hospital Brest, France.

ABSTRACT

Background: The purpose of this study was to detect chronic obstructive pulmonary disease (COPD) among smokers seeking treatment for the first time in a smoking cessation clinic and to assess the predictors of positive screening.

Methods: This study was based on a multicenter survey with questionnaires (Richmond, Fagerstrom, clinical signs) and spirometry miniaturized. Data were analyzed with SAS® by Pearson chi-square test, the test of analysis of variance, Spearman correlation coefficient, and multivariate logistic regression step down.

Findings: 1918 patients were assessed for eligibility and only 1737 were included. The report forced expiratory volume in 1 second (FEV1/FEV6) was < 0.8 for 33.2% of smokers and < 0.7 for 7.5% of them. People with likely COPD had more dyspnea (P < 0.010) and chronic bronchitis (CB) (P < 0.010). In multivariate analysis, CB, duration of smoking history since longer than 30 years, and dyspnea significantly increased the risk of being detected as COPD. The odds ratios of the above factors were 2.9, 4.1, and 4.5, respectively.

Conclusion: 7.5% of smokers were likely COPD. Patient's risk factors, such as the presence of CB, smoking addiction for longer than 30 years, or dyspnea, were predictive of a positive screening for COPD.

No MeSH data available.


Related in: MedlinePlus

Flow of the patients throughout the studyCOPD: Chronic obstructive pulmonary disease
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f1-AHJ-08-001: Flow of the patients throughout the studyCOPD: Chronic obstructive pulmonary disease

Mentions: This was a prospective multicenter study of 1918 smokers selected from 16 French smoking cessation clinics between January and December 2009. Inclusion criteria were active smokers, coming for the first time in one of these clinics, and who consented to take part in the study. The exclusion criterion was a history of pneumothorax of < 6 months. Furthermore, after patient’s eligibility assessment, those with known COPD or asthma prior to the first consultation were excluded from data processing to avoid possible selection bias. Figure 1 describes the flow of patients from selection to data analysis. This study was in accordance with ethical standards of hospitals. Subjects were informed, and consent was obtained.


Screening for Chronic Obstructive Pulmonary Disease in Smoking Cessation Clinic in France.

Richard P, Gilles H, Alavi Z, Christine L, Maryline le B, Ronan G, Laurence P, Jean P, Jean-Dominique D - Addict Health (2016)

Flow of the patients throughout the studyCOPD: Chronic obstructive pulmonary disease
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4836757&req=5

f1-AHJ-08-001: Flow of the patients throughout the studyCOPD: Chronic obstructive pulmonary disease
Mentions: This was a prospective multicenter study of 1918 smokers selected from 16 French smoking cessation clinics between January and December 2009. Inclusion criteria were active smokers, coming for the first time in one of these clinics, and who consented to take part in the study. The exclusion criterion was a history of pneumothorax of < 6 months. Furthermore, after patient’s eligibility assessment, those with known COPD or asthma prior to the first consultation were excluded from data processing to avoid possible selection bias. Figure 1 describes the flow of patients from selection to data analysis. This study was in accordance with ethical standards of hospitals. Subjects were informed, and consent was obtained.

Bottom Line: This study was based on a multicenter survey with questionnaires (Richmond, Fagerstrom, clinical signs) and spirometry miniaturized.Data were analyzed with SAS® by Pearson chi-square test, the test of analysis of variance, Spearman correlation coefficient, and multivariate logistic regression step down. 1918 patients were assessed for eligibility and only 1737 were included.The report forced expiratory volume in 1 second (FEV1/FEV6) was < 0.8 for 33.2% of smokers and < 0.7 for 7.5% of them.

View Article: PubMed Central - PubMed

Affiliation: Tobaccology Center, University Hospital Brest, France.

ABSTRACT

Background: The purpose of this study was to detect chronic obstructive pulmonary disease (COPD) among smokers seeking treatment for the first time in a smoking cessation clinic and to assess the predictors of positive screening.

Methods: This study was based on a multicenter survey with questionnaires (Richmond, Fagerstrom, clinical signs) and spirometry miniaturized. Data were analyzed with SAS® by Pearson chi-square test, the test of analysis of variance, Spearman correlation coefficient, and multivariate logistic regression step down.

Findings: 1918 patients were assessed for eligibility and only 1737 were included. The report forced expiratory volume in 1 second (FEV1/FEV6) was < 0.8 for 33.2% of smokers and < 0.7 for 7.5% of them. People with likely COPD had more dyspnea (P < 0.010) and chronic bronchitis (CB) (P < 0.010). In multivariate analysis, CB, duration of smoking history since longer than 30 years, and dyspnea significantly increased the risk of being detected as COPD. The odds ratios of the above factors were 2.9, 4.1, and 4.5, respectively.

Conclusion: 7.5% of smokers were likely COPD. Patient's risk factors, such as the presence of CB, smoking addiction for longer than 30 years, or dyspnea, were predictive of a positive screening for COPD.

No MeSH data available.


Related in: MedlinePlus