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Continuing to Confront COPD International Patient Survey: Economic Impact of COPD in 12 Countries.

Foo J, Landis SH, Maskell J, Oh YM, van der Molen T, Han MK, Mannino DM, Ichinose M, Punekar Y - PLoS ONE (2016)

Bottom Line: Indirect costs were calculated from work loss values using the Work Productivity and Activity Impairment scale.Combined direct and indirect costs estimated the total societal costs per patient.The annual direct costs of COPD ranged from $504 (South Korea) to $9,981 (USA), with inpatient hospitalisations (5 countries) and home oxygen therapy (3 countries) being the key drivers of direct costs.

View Article: PubMed Central - PubMed

Affiliation: Health Outcomes, GlaxoSmithKline, Uxbridge, United Kingdom.

ABSTRACT

Background: The Continuing to Confront COPD International Patient Survey estimated the prevalence and burden of COPD across 12 countries. Using data from this survey we evaluated the economic impact of COPD.

Methods: This cross-sectional, population-based survey questioned 4,343 subjects aged 40 years and older, fulfilling a case definition of COPD based on self-reported physician diagnosis or symptomatology. Direct cost measures were based on exacerbations of COPD (treated and those requiring emergency department visits and/or hospitalisation), contacts with healthcare professionals, and COPD medications. Indirect costs were calculated from work loss values using the Work Productivity and Activity Impairment scale. Combined direct and indirect costs estimated the total societal costs per patient.

Results: The annual direct costs of COPD ranged from $504 (South Korea) to $9,981 (USA), with inpatient hospitalisations (5 countries) and home oxygen therapy (3 countries) being the key drivers of direct costs. The proportion of patients completely prevented from working due to their COPD ranged from 6% (Italy) to 52% (USA and UK) with 8 countries reporting this to be ≥20%. Total societal costs per patient varied widely from $1,721 (Russia) to $30,826 (USA) but a consistent pattern across countries showed greater costs among those with increased burden of COPD (symptoms, health status and more severe disease) and a greater number of comorbidities.

Conclusions: The economic burden of COPD is considerable across countries, and requires targeted resources to optimise COPD management encompassing the control of symptoms, prevention of exacerbations and effective treatment of comorbidities. Strategies to allow COPD patients to remain in work are important for addressing the substantial wider societal costs.

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Related in: MedlinePlus

Annual direct costs per patient of COPD and percentage breakdown by cost type: Continuing to Confront COPD International Patient Survey, 2012–13.Additional costs not shown: Nursing visits: NL (1%); Influenza vaccination: Brazil (2%); SK (2%); NL (1%); Abbreviations: USA, United States of America, UK, United Kingdom, NL, Netherlands; SK, South Korea
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pone.0152618.g001: Annual direct costs per patient of COPD and percentage breakdown by cost type: Continuing to Confront COPD International Patient Survey, 2012–13.Additional costs not shown: Nursing visits: NL (1%); Influenza vaccination: Brazil (2%); SK (2%); NL (1%); Abbreviations: USA, United States of America, UK, United Kingdom, NL, Netherlands; SK, South Korea

Mentions: The annual direct cost of COPD per patient ranged from $504 in South Korea to $9,981 in the USA (Fig 1). The breakdown of direct costs varied across countries. In five countries inpatient hospitalisations was the largest contributor to direct costs: France [54%], Germany [53%], Spain [50%], the USA [33%], and South Korea [26%]) (Fig 1). General Practitioner visits contributed substantially to the direct costs in Mexico (30%), Japan (28%) and the UK (26%) whilst specialist visits contributed at least one quarter of the direct costs in Japan (28%), the UK (26%), and the USA (26%). Home oxygen therapy accounted for the largest individual direct costs in Brazil (28%), Russia (33%), France (30%), and Italy (40%). Prescription medication costs for COPD accounted for between 4 and 33% of costs across countries, being the lowest in France (4%), Mexico (8%) and Japan (9%), and the highest in Brazil (24%), Russia (24%) and the Netherlands (33%).


Continuing to Confront COPD International Patient Survey: Economic Impact of COPD in 12 Countries.

Foo J, Landis SH, Maskell J, Oh YM, van der Molen T, Han MK, Mannino DM, Ichinose M, Punekar Y - PLoS ONE (2016)

Annual direct costs per patient of COPD and percentage breakdown by cost type: Continuing to Confront COPD International Patient Survey, 2012–13.Additional costs not shown: Nursing visits: NL (1%); Influenza vaccination: Brazil (2%); SK (2%); NL (1%); Abbreviations: USA, United States of America, UK, United Kingdom, NL, Netherlands; SK, South Korea
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4836731&req=5

pone.0152618.g001: Annual direct costs per patient of COPD and percentage breakdown by cost type: Continuing to Confront COPD International Patient Survey, 2012–13.Additional costs not shown: Nursing visits: NL (1%); Influenza vaccination: Brazil (2%); SK (2%); NL (1%); Abbreviations: USA, United States of America, UK, United Kingdom, NL, Netherlands; SK, South Korea
Mentions: The annual direct cost of COPD per patient ranged from $504 in South Korea to $9,981 in the USA (Fig 1). The breakdown of direct costs varied across countries. In five countries inpatient hospitalisations was the largest contributor to direct costs: France [54%], Germany [53%], Spain [50%], the USA [33%], and South Korea [26%]) (Fig 1). General Practitioner visits contributed substantially to the direct costs in Mexico (30%), Japan (28%) and the UK (26%) whilst specialist visits contributed at least one quarter of the direct costs in Japan (28%), the UK (26%), and the USA (26%). Home oxygen therapy accounted for the largest individual direct costs in Brazil (28%), Russia (33%), France (30%), and Italy (40%). Prescription medication costs for COPD accounted for between 4 and 33% of costs across countries, being the lowest in France (4%), Mexico (8%) and Japan (9%), and the highest in Brazil (24%), Russia (24%) and the Netherlands (33%).

Bottom Line: Indirect costs were calculated from work loss values using the Work Productivity and Activity Impairment scale.Combined direct and indirect costs estimated the total societal costs per patient.The annual direct costs of COPD ranged from $504 (South Korea) to $9,981 (USA), with inpatient hospitalisations (5 countries) and home oxygen therapy (3 countries) being the key drivers of direct costs.

View Article: PubMed Central - PubMed

Affiliation: Health Outcomes, GlaxoSmithKline, Uxbridge, United Kingdom.

ABSTRACT

Background: The Continuing to Confront COPD International Patient Survey estimated the prevalence and burden of COPD across 12 countries. Using data from this survey we evaluated the economic impact of COPD.

Methods: This cross-sectional, population-based survey questioned 4,343 subjects aged 40 years and older, fulfilling a case definition of COPD based on self-reported physician diagnosis or symptomatology. Direct cost measures were based on exacerbations of COPD (treated and those requiring emergency department visits and/or hospitalisation), contacts with healthcare professionals, and COPD medications. Indirect costs were calculated from work loss values using the Work Productivity and Activity Impairment scale. Combined direct and indirect costs estimated the total societal costs per patient.

Results: The annual direct costs of COPD ranged from $504 (South Korea) to $9,981 (USA), with inpatient hospitalisations (5 countries) and home oxygen therapy (3 countries) being the key drivers of direct costs. The proportion of patients completely prevented from working due to their COPD ranged from 6% (Italy) to 52% (USA and UK) with 8 countries reporting this to be ≥20%. Total societal costs per patient varied widely from $1,721 (Russia) to $30,826 (USA) but a consistent pattern across countries showed greater costs among those with increased burden of COPD (symptoms, health status and more severe disease) and a greater number of comorbidities.

Conclusions: The economic burden of COPD is considerable across countries, and requires targeted resources to optimise COPD management encompassing the control of symptoms, prevention of exacerbations and effective treatment of comorbidities. Strategies to allow COPD patients to remain in work are important for addressing the substantial wider societal costs.

Show MeSH
Related in: MedlinePlus