Limits...
A global amnesia associated with the specific variant of posterior reversible encephalopathy syndrome (PRES) that developed due to severe preeclampsia and malignant hypertension.

Borovac JA, Božić J, Žaja N, Kolić K, Hrboka V - Oxf Med Case Reports (2016)

Bottom Line: A post-partum magnetic resonance imaging of the brain in FLAIR mode revealed multiple cortico-subcortical areas of hyperintense signals suggestive of edematous lesions that chiefly involved occipital and parietal lobes with additional atypical manifestations.Such radiologic findings suggested a posterior reversible encephalopathy syndrome variant with the global amnesia as an extraordinary constituent.This unique feature should be acknowledged when treating a preeclamptic or hypertensive patient that exhibits neurological symptomatology and vision disturbances.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Pathophysiology , University of Split School of Medicine , Šoltanska 2, 21 000 Split , Croatia.

ABSTRACT
A case is reported of a 26-year-old primiparous woman in the 32nd week of gestation who presented to the emergency department with the symptoms of a severe headache, nausea and vomiting. The patient was diagnosed with preeclampsia that later progressed to eclampsia. This state was characterized by a sudden onset of a headache and diplopia that advanced to cortical blindness and precipitated significant alterations in mental status, most notable being global amnesia that resolved within 48 h. A post-partum magnetic resonance imaging of the brain in FLAIR mode revealed multiple cortico-subcortical areas of hyperintense signals suggestive of edematous lesions that chiefly involved occipital and parietal lobes with additional atypical manifestations. Such radiologic findings suggested a posterior reversible encephalopathy syndrome variant with the global amnesia as an extraordinary constituent. This unique feature should be acknowledged when treating a preeclamptic or hypertensive patient that exhibits neurological symptomatology and vision disturbances.

No MeSH data available.


Related in: MedlinePlus

A horizontal FLAIR MRI mode showing hyperintense vasogenic edematous lesions in parietal, temporo-occipital, frontal and periventricular brain regions. 
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4836601&req=5

OMW016F1: A horizontal FLAIR MRI mode showing hyperintense vasogenic edematous lesions in parietal, temporo-occipital, frontal and periventricular brain regions. 

Mentions: A primiparous, 26-year-old female in the 32nd week of gestation was admitted to the emergency department with the symptoms of preeclampsia. The arterial blood pressure (BP) of 190/110 mmHg was measured, while the antihypertensive therapy consisted of urapidil (25 mg, IV), amlodipine (10 mg, per os) and methyldopa (3 × 500 mg daily, per os). Likewise, MgSO4 was administered for seizure prevention (40 + 60 ml 0.9% NaCl, IV). Regardless of therapeutic management, preeclampsia translated into eclampsia. An emergency delivery via cesarean section was performed, and she was then treated in the clinical context of HELLP syndrome within the gynecology intensive care unit (ICU) since blood analysis revealed hemolysis (hemoglobin count of <90 g/l and dysmorphic erythrocytes in peripheral blood smear), elevated liver enzymes [aspartate aminotransferase (AST) level of 100 U/l] and a low platelet count of 72 × 109/l. A fluid-attenuated inversion recovery (FLAIR) mode of the MRI of the brain was performed to assess the neurologic complications, and it revealed bilateral brain edema (hyperintense lesions) in occipital and parietal lobes, with additional cerebellar, periventricular, temporo-occipital and frontal cortex lesions. These findings suggested a possible variant of PRES (Fig. 1 ).Figure 1:


A global amnesia associated with the specific variant of posterior reversible encephalopathy syndrome (PRES) that developed due to severe preeclampsia and malignant hypertension.

Borovac JA, Božić J, Žaja N, Kolić K, Hrboka V - Oxf Med Case Reports (2016)

A horizontal FLAIR MRI mode showing hyperintense vasogenic edematous lesions in parietal, temporo-occipital, frontal and periventricular brain regions. 
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4836601&req=5

OMW016F1: A horizontal FLAIR MRI mode showing hyperintense vasogenic edematous lesions in parietal, temporo-occipital, frontal and periventricular brain regions. 
Mentions: A primiparous, 26-year-old female in the 32nd week of gestation was admitted to the emergency department with the symptoms of preeclampsia. The arterial blood pressure (BP) of 190/110 mmHg was measured, while the antihypertensive therapy consisted of urapidil (25 mg, IV), amlodipine (10 mg, per os) and methyldopa (3 × 500 mg daily, per os). Likewise, MgSO4 was administered for seizure prevention (40 + 60 ml 0.9% NaCl, IV). Regardless of therapeutic management, preeclampsia translated into eclampsia. An emergency delivery via cesarean section was performed, and she was then treated in the clinical context of HELLP syndrome within the gynecology intensive care unit (ICU) since blood analysis revealed hemolysis (hemoglobin count of <90 g/l and dysmorphic erythrocytes in peripheral blood smear), elevated liver enzymes [aspartate aminotransferase (AST) level of 100 U/l] and a low platelet count of 72 × 109/l. A fluid-attenuated inversion recovery (FLAIR) mode of the MRI of the brain was performed to assess the neurologic complications, and it revealed bilateral brain edema (hyperintense lesions) in occipital and parietal lobes, with additional cerebellar, periventricular, temporo-occipital and frontal cortex lesions. These findings suggested a possible variant of PRES (Fig. 1 ).Figure 1:

Bottom Line: A post-partum magnetic resonance imaging of the brain in FLAIR mode revealed multiple cortico-subcortical areas of hyperintense signals suggestive of edematous lesions that chiefly involved occipital and parietal lobes with additional atypical manifestations.Such radiologic findings suggested a posterior reversible encephalopathy syndrome variant with the global amnesia as an extraordinary constituent.This unique feature should be acknowledged when treating a preeclamptic or hypertensive patient that exhibits neurological symptomatology and vision disturbances.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Pathophysiology , University of Split School of Medicine , Šoltanska 2, 21 000 Split , Croatia.

ABSTRACT
A case is reported of a 26-year-old primiparous woman in the 32nd week of gestation who presented to the emergency department with the symptoms of a severe headache, nausea and vomiting. The patient was diagnosed with preeclampsia that later progressed to eclampsia. This state was characterized by a sudden onset of a headache and diplopia that advanced to cortical blindness and precipitated significant alterations in mental status, most notable being global amnesia that resolved within 48 h. A post-partum magnetic resonance imaging of the brain in FLAIR mode revealed multiple cortico-subcortical areas of hyperintense signals suggestive of edematous lesions that chiefly involved occipital and parietal lobes with additional atypical manifestations. Such radiologic findings suggested a posterior reversible encephalopathy syndrome variant with the global amnesia as an extraordinary constituent. This unique feature should be acknowledged when treating a preeclamptic or hypertensive patient that exhibits neurological symptomatology and vision disturbances.

No MeSH data available.


Related in: MedlinePlus