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Quantification of the Effect of Pressure Wire Drift on the Diagnostic Performance of Fractional Flow Reserve, Instantaneous Wave-Free Ratio, and Whole-Cycle Pd/Pa.

Cook CM, Ahmad Y, Shun-Shin MJ, Nijjer S, Petraco R, Al-Lamee R, Mayet J, Francis DP, Sen S, Davies JE - Circ Cardiovasc Interv (2016)

Bottom Line: Both FFR and iFR had significantly lower misclassification than whole-cycle Pd/Pa (P<0.001).There was no statistically significant difference between the diagnostic performance of FFR and iFR (P=0.125).Whole-cycle Pd/Pa is more vulnerable to such reclassification than FFR and iFR.

View Article: PubMed Central - PubMed

Affiliation: From the International Centre for Circulatory Health, National Heart & Lung Institute, Imperial College NHS Trust, United Kingdom. christopher.cook@nhs.net.

No MeSH data available.


Related in: MedlinePlus

Assessing pressure wire drift. An example of a raw hemodynamic pressure trace with −2 mm Hg of simulated pressure wire drift. Red indicates aortic pressure (Pa), blue indicates distal coronary pressure (Pd), and yellow indicates distal coronary pressure with −2 mm Hg drift.
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Figure 1: Assessing pressure wire drift. An example of a raw hemodynamic pressure trace with −2 mm Hg of simulated pressure wire drift. Red indicates aortic pressure (Pa), blue indicates distal coronary pressure (Pd), and yellow indicates distal coronary pressure with −2 mm Hg drift.

Mentions: Pressure wire drift was assessed by offsetting the distal intracoronary pressure trace relative to its original position by 1 mm Hg increments from −2 to +2 mm Hg in the custom software analysis package (Figure 1). Aortic pressure drift was assessed by offsetting the aortic pressure trace by 1 mm Hg increments from −2 mm Hg to +2 mm Hg in the custom software analysis package.


Quantification of the Effect of Pressure Wire Drift on the Diagnostic Performance of Fractional Flow Reserve, Instantaneous Wave-Free Ratio, and Whole-Cycle Pd/Pa.

Cook CM, Ahmad Y, Shun-Shin MJ, Nijjer S, Petraco R, Al-Lamee R, Mayet J, Francis DP, Sen S, Davies JE - Circ Cardiovasc Interv (2016)

Assessing pressure wire drift. An example of a raw hemodynamic pressure trace with −2 mm Hg of simulated pressure wire drift. Red indicates aortic pressure (Pa), blue indicates distal coronary pressure (Pd), and yellow indicates distal coronary pressure with −2 mm Hg drift.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4836560&req=5

Figure 1: Assessing pressure wire drift. An example of a raw hemodynamic pressure trace with −2 mm Hg of simulated pressure wire drift. Red indicates aortic pressure (Pa), blue indicates distal coronary pressure (Pd), and yellow indicates distal coronary pressure with −2 mm Hg drift.
Mentions: Pressure wire drift was assessed by offsetting the distal intracoronary pressure trace relative to its original position by 1 mm Hg increments from −2 to +2 mm Hg in the custom software analysis package (Figure 1). Aortic pressure drift was assessed by offsetting the aortic pressure trace by 1 mm Hg increments from −2 mm Hg to +2 mm Hg in the custom software analysis package.

Bottom Line: Both FFR and iFR had significantly lower misclassification than whole-cycle Pd/Pa (P<0.001).There was no statistically significant difference between the diagnostic performance of FFR and iFR (P=0.125).Whole-cycle Pd/Pa is more vulnerable to such reclassification than FFR and iFR.

View Article: PubMed Central - PubMed

Affiliation: From the International Centre for Circulatory Health, National Heart & Lung Institute, Imperial College NHS Trust, United Kingdom. christopher.cook@nhs.net.

No MeSH data available.


Related in: MedlinePlus