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Coronal diffusion-weighted magnetic resonance imaging of the kidney: agreement with axial diffusion-weighted magnetic imaging in terms of apparent diffusion coefficient values.

Wang HY, Wang J, Tang YH, Ye HY, Ma L - Chin. Med. J. (2015)

Bottom Line: The signal-to-noise ratios (SNRs) of the two DW-MRI sequences were measured and statistically compared using the paired t-test.The SNR of coronal DW-MR images was statistically inferior to that of axial DW-MR images (P < 0.001).In addition, 94.1% (32/34), 94.1% (32/34), and 97.1% (31/34) of the ADC bias was inside the limits of agreement in terms of the mean ADC values of the left kidneys, right kidneys, and bilateral kidneys when coronal and axial DWI-MRI were compared.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Chinese People's Liberation Army General Hospital, Beijing 100853, China.

ABSTRACT

Background: Coronal diffusion-weighted magnetic resonance imaging (DW-MRI) and apparent diffusion coefficient (ADC) values have gradually become applied (following conventional axial DW-MRI) in the renal analysis. To explore whether data obtained using coronal DW-MRI are comparable with those derived using axial DW-MRI, this preliminary study sought to assess the agreement in renal ADC values between coronal DW-MRI and axial DW-MRI.

Methods: Thirty-four healthy volunteers were enrolled in the study; written consents were obtained. All subjects underwent respiratory-triggered axial and coronal DW-MRI using a 1.5-MR system with b values of 0 and 800 s/mm 2 . The signal-to-noise ratios (SNRs) of the two DW-MRI sequences were measured and statistically compared using the paired t-test. The extent of agreement of ADC values of the upper pole, mid-pole, and lower pole of the kidney; the mean ADC values of the left kidney and right kidney; and the mean ADC values of the bilateral kidneys were evaluated via calculation of intraclass correlation coefficients (ICCs) or Bland-Altman method between the two DW-MRI sequences.

Results: The SNR of coronal DW-MR images was statistically inferior to that of axial DW-MR images (P < 0.001). The ICCs of the ADC values of each region of interest, and the mean ADC values of bilateral kidneys, between the two sequences, were greater than 0.5, and the mean ADCs of the bilateral kidneys demonstrated the highest ICC (0.869; 95% confidence interval: 0.739-0.935). In addition, 94.1% (32/34), 94.1% (32/34), and 97.1% (31/34) of the ADC bias was inside the limits of agreement in terms of the mean ADC values of the left kidneys, right kidneys, and bilateral kidneys when coronal and axial DWI-MRI were compared.

Conclusions: ADC values derived using coronal DW-MRI exhibited moderate-to-good agreement to those of axial DW-MRI, rendering the former an additional useful DW-MRI method, and causing the ADC values derived using the two types of DW-MRI to be comparable.

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Axial Diffusion-weighted magnetic resonance images and apparent diffusion coefficient (ADC) maps of a healthy female volunteer. Three region of interests were placed in the upper pole (a, b), middle portion (c, d), and lower pole (e, f) of the bilateral kidneys, respectively. The mean ADC values of the left and right kidneys were 2.140 × 10−3 mm2/s and 2.170 × 10−3 mm2/s, respectively.
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Figure 1: Axial Diffusion-weighted magnetic resonance images and apparent diffusion coefficient (ADC) maps of a healthy female volunteer. Three region of interests were placed in the upper pole (a, b), middle portion (c, d), and lower pole (e, f) of the bilateral kidneys, respectively. The mean ADC values of the left and right kidneys were 2.140 × 10−3 mm2/s and 2.170 × 10−3 mm2/s, respectively.

Mentions: The signal-to-noise ratios (SNRs) of the two DW imaging sequences were measured on a GE Workstation (Version Advantage 4.3), and were calculated according to the equation: SNR = SIkidney/noise, where SI is signal intensity. To measure ADC values, one radiologist who had performed abdominal MRI for 5 years placed three regions of interest (ROI) in the upper, middle, and lower poles of the kidney, on both axial [Figure 1a–e] and coronal DW-MR images [Figure 2a], and the ROIs were automatically copied onto ADC maps [Figures 1b, d, f and 2b]. The ROIs were approximately 100 mm2 in area. The ADC value of each ROI, the mean ADC values of each kidney, and the mean ADC values of the bilateral kidneys were calculated. The ADC value of each ROI was calculated using the following equation: ADC mm2/s = ln[SI (b0)/SI (b1)]/(b1 − b0), where SI (b0) and SI (b1) are the signal intensities in the ROI obtained using two different gradient factors (b0 and b1).


Coronal diffusion-weighted magnetic resonance imaging of the kidney: agreement with axial diffusion-weighted magnetic imaging in terms of apparent diffusion coefficient values.

Wang HY, Wang J, Tang YH, Ye HY, Ma L - Chin. Med. J. (2015)

Axial Diffusion-weighted magnetic resonance images and apparent diffusion coefficient (ADC) maps of a healthy female volunteer. Three region of interests were placed in the upper pole (a, b), middle portion (c, d), and lower pole (e, f) of the bilateral kidneys, respectively. The mean ADC values of the left and right kidneys were 2.140 × 10−3 mm2/s and 2.170 × 10−3 mm2/s, respectively.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4836254&req=5

Figure 1: Axial Diffusion-weighted magnetic resonance images and apparent diffusion coefficient (ADC) maps of a healthy female volunteer. Three region of interests were placed in the upper pole (a, b), middle portion (c, d), and lower pole (e, f) of the bilateral kidneys, respectively. The mean ADC values of the left and right kidneys were 2.140 × 10−3 mm2/s and 2.170 × 10−3 mm2/s, respectively.
Mentions: The signal-to-noise ratios (SNRs) of the two DW imaging sequences were measured on a GE Workstation (Version Advantage 4.3), and were calculated according to the equation: SNR = SIkidney/noise, where SI is signal intensity. To measure ADC values, one radiologist who had performed abdominal MRI for 5 years placed three regions of interest (ROI) in the upper, middle, and lower poles of the kidney, on both axial [Figure 1a–e] and coronal DW-MR images [Figure 2a], and the ROIs were automatically copied onto ADC maps [Figures 1b, d, f and 2b]. The ROIs were approximately 100 mm2 in area. The ADC value of each ROI, the mean ADC values of each kidney, and the mean ADC values of the bilateral kidneys were calculated. The ADC value of each ROI was calculated using the following equation: ADC mm2/s = ln[SI (b0)/SI (b1)]/(b1 − b0), where SI (b0) and SI (b1) are the signal intensities in the ROI obtained using two different gradient factors (b0 and b1).

Bottom Line: The signal-to-noise ratios (SNRs) of the two DW-MRI sequences were measured and statistically compared using the paired t-test.The SNR of coronal DW-MR images was statistically inferior to that of axial DW-MR images (P < 0.001).In addition, 94.1% (32/34), 94.1% (32/34), and 97.1% (31/34) of the ADC bias was inside the limits of agreement in terms of the mean ADC values of the left kidneys, right kidneys, and bilateral kidneys when coronal and axial DWI-MRI were compared.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Chinese People's Liberation Army General Hospital, Beijing 100853, China.

ABSTRACT

Background: Coronal diffusion-weighted magnetic resonance imaging (DW-MRI) and apparent diffusion coefficient (ADC) values have gradually become applied (following conventional axial DW-MRI) in the renal analysis. To explore whether data obtained using coronal DW-MRI are comparable with those derived using axial DW-MRI, this preliminary study sought to assess the agreement in renal ADC values between coronal DW-MRI and axial DW-MRI.

Methods: Thirty-four healthy volunteers were enrolled in the study; written consents were obtained. All subjects underwent respiratory-triggered axial and coronal DW-MRI using a 1.5-MR system with b values of 0 and 800 s/mm 2 . The signal-to-noise ratios (SNRs) of the two DW-MRI sequences were measured and statistically compared using the paired t-test. The extent of agreement of ADC values of the upper pole, mid-pole, and lower pole of the kidney; the mean ADC values of the left kidney and right kidney; and the mean ADC values of the bilateral kidneys were evaluated via calculation of intraclass correlation coefficients (ICCs) or Bland-Altman method between the two DW-MRI sequences.

Results: The SNR of coronal DW-MR images was statistically inferior to that of axial DW-MR images (P < 0.001). The ICCs of the ADC values of each region of interest, and the mean ADC values of bilateral kidneys, between the two sequences, were greater than 0.5, and the mean ADCs of the bilateral kidneys demonstrated the highest ICC (0.869; 95% confidence interval: 0.739-0.935). In addition, 94.1% (32/34), 94.1% (32/34), and 97.1% (31/34) of the ADC bias was inside the limits of agreement in terms of the mean ADC values of the left kidneys, right kidneys, and bilateral kidneys when coronal and axial DWI-MRI were compared.

Conclusions: ADC values derived using coronal DW-MRI exhibited moderate-to-good agreement to those of axial DW-MRI, rendering the former an additional useful DW-MRI method, and causing the ADC values derived using the two types of DW-MRI to be comparable.

Show MeSH
Related in: MedlinePlus