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Seasonality and shift in age-specific malaria prevalence and incidence in Binko and Carrière villages close to the lake in Selingué, Mali.

Touré M, Sanogo D, Dembele S, Diawara SI, Oppfeldt K, Schiøler KL, Haidara DB, Traoré SF, Alifrangis M, Konradsen F, Doumbia S - Malar. J. (2016)

Bottom Line: The number of clinical episodes per year was determined among the children in the cohort.Children 6-9 years old were at least twice more likely to carry parasites than children up to 5 years old.The peak incidence was observed between August and October (end of the rainy season), but the incidence remained high until December.

View Article: PubMed Central - PubMed

Affiliation: Malaria Research and Training Centre-Faculty of Medicine and Dentistry, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, BP 1805, Mali.

ABSTRACT

Background: Malaria transmission in Mali is seasonal and peaks at the end of the rainy season in October. This study assessed the seasonal variations in the epidemiology of malaria among children under 10 years of age living in two villages in Selingué: Carrière, located along the Sankarani River but distant from the hydroelectric dam, and Binko, near irrigated rice fields, close to the dam. The aim of this study was to provide baseline data, seasonal pattern and age distribution of malaria incidence in two sites situated close to a lake in Selingué.

Methods: Geographically, Selingué area is located in the basin of Sakanrani and belongs to the district of Yanfolila in the third administrative region of Mali, Sikasso. Two cross-sectional surveys were conducted in October 2010 (end of transmission season) and in July 2011 (beginning of transmission season) to determine the point prevalence of asymptomatic parasitaemia, and anaemia among the children. Cumulative incidence of malaria per month was determined in a cohort of 549 children through active and passive case detection from November 2010 through October 2011. The number of clinical episodes per year was determined among the children in the cohort. Logistic regression was used to determine risk factors for malaria.

Results: The prevalence of malaria parasitaemia varied significantly between villages with a strong seasonality in Carrière (52.0-18.9 % in October 2010 and July 2011, respectively) compared with Binko (29.8-23.8 % in October 2010 and July 2011, respectively). Children 6-9 years old were at least twice more likely to carry parasites than children up to 5 years old. For malaria incidence, 64.8-71.9 % of all children experienced at least one episode of clinical malaria in Binko and Carrière, respectively. The peak incidence was observed between August and October (end of the rainy season), but the incidence remained high until December. Surprisingly, the risk of clinical malaria was two- to nine-fold higher among children 5-9 years old compared to younger children.

Conclusions: A shift in the peak of clinical episodes from children under 5-9 years of age calls for expanding control interventions, such as seasonal malaria chemoprophylaxis targeting the peak transmission months.

No MeSH data available.


Related in: MedlinePlus

Maps of the study sites, Carrière and Binko. Geographic coordinates of study sites were projected on Google Earth image of June 2013 to illustrate the location of each site according to their position by the lake
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Fig1: Maps of the study sites, Carrière and Binko. Geographic coordinates of study sites were projected on Google Earth image of June 2013 to illustrate the location of each site according to their position by the lake

Mentions: In Mali, the agro-hydropower dam of Sélingué was built in 1982 and represents the most important centre of energy production in Mali, of approximately 200 million kW-h a year. The presence of an artificial lake introduces a change in the environmental setting of Sélingué with villages located in a dry area such as Carrière, and others in more humid areas with permanent presence of water pools due to irrigation, such as Binko (Fig. 1). The population in villages around Sélingué has two main activities: agriculture in Binko surrounding the irrigated field, while in Carrière fishing is more frequent. The dominant ethnic group is Malinke in the agricultural areas, while Bozo are dominant in the fishing areas. This latter group also presents a high rate of movement within other fishing regions of Mali, such as Mopti and Ségou.Fig. 1


Seasonality and shift in age-specific malaria prevalence and incidence in Binko and Carrière villages close to the lake in Selingué, Mali.

Touré M, Sanogo D, Dembele S, Diawara SI, Oppfeldt K, Schiøler KL, Haidara DB, Traoré SF, Alifrangis M, Konradsen F, Doumbia S - Malar. J. (2016)

Maps of the study sites, Carrière and Binko. Geographic coordinates of study sites were projected on Google Earth image of June 2013 to illustrate the location of each site according to their position by the lake
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4836195&req=5

Fig1: Maps of the study sites, Carrière and Binko. Geographic coordinates of study sites were projected on Google Earth image of June 2013 to illustrate the location of each site according to their position by the lake
Mentions: In Mali, the agro-hydropower dam of Sélingué was built in 1982 and represents the most important centre of energy production in Mali, of approximately 200 million kW-h a year. The presence of an artificial lake introduces a change in the environmental setting of Sélingué with villages located in a dry area such as Carrière, and others in more humid areas with permanent presence of water pools due to irrigation, such as Binko (Fig. 1). The population in villages around Sélingué has two main activities: agriculture in Binko surrounding the irrigated field, while in Carrière fishing is more frequent. The dominant ethnic group is Malinke in the agricultural areas, while Bozo are dominant in the fishing areas. This latter group also presents a high rate of movement within other fishing regions of Mali, such as Mopti and Ségou.Fig. 1

Bottom Line: The number of clinical episodes per year was determined among the children in the cohort.Children 6-9 years old were at least twice more likely to carry parasites than children up to 5 years old.The peak incidence was observed between August and October (end of the rainy season), but the incidence remained high until December.

View Article: PubMed Central - PubMed

Affiliation: Malaria Research and Training Centre-Faculty of Medicine and Dentistry, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, BP 1805, Mali.

ABSTRACT

Background: Malaria transmission in Mali is seasonal and peaks at the end of the rainy season in October. This study assessed the seasonal variations in the epidemiology of malaria among children under 10 years of age living in two villages in Selingué: Carrière, located along the Sankarani River but distant from the hydroelectric dam, and Binko, near irrigated rice fields, close to the dam. The aim of this study was to provide baseline data, seasonal pattern and age distribution of malaria incidence in two sites situated close to a lake in Selingué.

Methods: Geographically, Selingué area is located in the basin of Sakanrani and belongs to the district of Yanfolila in the third administrative region of Mali, Sikasso. Two cross-sectional surveys were conducted in October 2010 (end of transmission season) and in July 2011 (beginning of transmission season) to determine the point prevalence of asymptomatic parasitaemia, and anaemia among the children. Cumulative incidence of malaria per month was determined in a cohort of 549 children through active and passive case detection from November 2010 through October 2011. The number of clinical episodes per year was determined among the children in the cohort. Logistic regression was used to determine risk factors for malaria.

Results: The prevalence of malaria parasitaemia varied significantly between villages with a strong seasonality in Carrière (52.0-18.9 % in October 2010 and July 2011, respectively) compared with Binko (29.8-23.8 % in October 2010 and July 2011, respectively). Children 6-9 years old were at least twice more likely to carry parasites than children up to 5 years old. For malaria incidence, 64.8-71.9 % of all children experienced at least one episode of clinical malaria in Binko and Carrière, respectively. The peak incidence was observed between August and October (end of the rainy season), but the incidence remained high until December. Surprisingly, the risk of clinical malaria was two- to nine-fold higher among children 5-9 years old compared to younger children.

Conclusions: A shift in the peak of clinical episodes from children under 5-9 years of age calls for expanding control interventions, such as seasonal malaria chemoprophylaxis targeting the peak transmission months.

No MeSH data available.


Related in: MedlinePlus