Kidney biopsy. Optical microscopy showed significant in

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Reversible Fluindione-Induced Chronic Interstitial Nephritis. Crepin T, Bamoulid J, Courivaud C, Dahmani O, Felix S, Ducloux D - Case Rep Nephrol (2016) Bottom Line: Most cases occurred soon after the onset of treatment.We report a unique case of severe subacute fluindione-induced IN diagnosed 2 years after the treatment was begun.Renal function dramatically improved after fluindione withdrawal and steroid therapy. View Article: PubMed Central - PubMed Affiliation: Department of Nephrology, Dialysis, and Renal Transplantation, CHU Besançon, 25030 Besançon, France. ABSTRACT Fluindione is well known to induce acute drug-induced interstitial nephritis (IN). Most cases occurred soon after the onset of treatment. We report a unique case of severe subacute fluindione-induced IN diagnosed 2 years after the treatment was begun. Renal function dramatically improved after fluindione withdrawal and steroid therapy. No MeSH data available. Related in: MedlinePlus	© Copyright Policy Related In: Results - Collection License Show All Figures getmorefigures.php?uid=PMC4835627&req=5 fig1: Kidney biopsy. Optical microscopy showed significant interstitial lymphocytic infiltration (HES). Mentions: Kidney biopsy was performed. Optical microscopy showed tubulointerstitial nephritis with marked inflammation T cell CD3+, few eosinophils, and severe fibrosis with tubular atrophy. Immunofluorescent studies did not reveal any immune deposits (Figures 1-2).

Reversible Fluindione-Induced Chronic Interstitial Nephritis.

Crepin T, Bamoulid J, Courivaud C, Dahmani O, Felix S, Ducloux D - Case Rep Nephrol (2016)

Bottom Line: Most cases occurred soon after the onset of treatment.We report a unique case of severe subacute fluindione-induced IN diagnosed 2 years after the treatment was begun.Renal function dramatically improved after fluindione withdrawal and steroid therapy.

View Article: PubMed Central - PubMed

Affiliation: Department of Nephrology, Dialysis, and Renal Transplantation, CHU Besançon, 25030 Besançon, France.

ABSTRACT

Fluindione is well known to induce acute drug-induced interstitial nephritis (IN). Most cases occurred soon after the onset of treatment. We report a unique case of severe subacute fluindione-induced IN diagnosed 2 years after the treatment was begun. Renal function dramatically improved after fluindione withdrawal and steroid therapy.

No MeSH data available.

Related in: MedlinePlus

Kidney biopsy. Optical microscopy showed significant interstitial lymphocytic infiltration (HES).

Related In: Results - Collection

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fig1: Kidney biopsy. Optical microscopy showed significant interstitial lymphocytic infiltration (HES).

Mentions: Kidney biopsy was performed. Optical microscopy showed tubulointerstitial nephritis with marked inflammation T cell CD3+, few eosinophils, and severe fibrosis with tubular atrophy. Immunofluorescent studies did not reveal any immune deposits (Figures 1-2).