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Knowledge and Perception about Clinical Research Shapes Behavior: Face to Face Survey in Korean General Public.

Choi YJ, Beck SH, Kang WY, Yoo S, Kim SY, Lee JS, Burt T, Kim TW - J. Korean Med. Sci. (2016)

Bottom Line: Treatment benefit was the single most influential reason for participation, followed by financial gain.Concern about safety was the main reason for refusal, succeeded by fear and lack of trust.Public awareness and educational programs addressing these negative perceptions and lack of knowledge will be effective in enhancing public engaged in clinical research.

View Article: PubMed Central - PubMed

Affiliation: Asan Medical Center, Clinical Trial Center, Seoul, Korea .

ABSTRACT
Considering general public as potential patients, identifying factors that hinder public participation poses great importance, especially in a research environment where demands for clinical trial participants outpace the supply. Hence, the aim of this study was to evaluate knowledge and perception about clinical research in general public. A total of 400 Seoul residents with no previous experience of clinical trial participation were selected, as representative of population in Seoul in terms of age and sex. To minimize selection bias, every fifth passer-by was invited to interview, and if in a cluster, person on the very right side was asked. To ensure the uniform use of survey, written instructions have been added to the questionnaire. Followed by pilot test in 40 subjects, the survey was administered face-to-face in December 2014. To investigate how perception shapes behavior, we compared perception scores in those who expressed willingness to participate and those who did not. Remarkably higher percentage of responders stated that they have heard of clinical research, and knew someone who participated (both, P < 0.001) compared to India. Yet, the percentage of responders expressed willingness to participate was 39.3%, a significantly lower rate than the result of the India (58.9% vs. 39.3%, P < 0.001). Treatment benefit was the single most influential reason for participation, followed by financial gain. Concern about safety was the main reason for refusal, succeeded by fear and lack of trust. Public awareness and educational programs addressing these negative perceptions and lack of knowledge will be effective in enhancing public engaged in clinical research.

No MeSH data available.


Most trusted source of clinical research information.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
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Figure 3: Most trusted source of clinical research information.

Mentions: The most trusted source of clinical research information was analysed. Academia was shown to be the single most trusted source, followed by medical doctors (Fig. 3).


Knowledge and Perception about Clinical Research Shapes Behavior: Face to Face Survey in Korean General Public.

Choi YJ, Beck SH, Kang WY, Yoo S, Kim SY, Lee JS, Burt T, Kim TW - J. Korean Med. Sci. (2016)

Most trusted source of clinical research information.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4835590&req=5

Figure 3: Most trusted source of clinical research information.
Mentions: The most trusted source of clinical research information was analysed. Academia was shown to be the single most trusted source, followed by medical doctors (Fig. 3).

Bottom Line: Treatment benefit was the single most influential reason for participation, followed by financial gain.Concern about safety was the main reason for refusal, succeeded by fear and lack of trust.Public awareness and educational programs addressing these negative perceptions and lack of knowledge will be effective in enhancing public engaged in clinical research.

View Article: PubMed Central - PubMed

Affiliation: Asan Medical Center, Clinical Trial Center, Seoul, Korea .

ABSTRACT
Considering general public as potential patients, identifying factors that hinder public participation poses great importance, especially in a research environment where demands for clinical trial participants outpace the supply. Hence, the aim of this study was to evaluate knowledge and perception about clinical research in general public. A total of 400 Seoul residents with no previous experience of clinical trial participation were selected, as representative of population in Seoul in terms of age and sex. To minimize selection bias, every fifth passer-by was invited to interview, and if in a cluster, person on the very right side was asked. To ensure the uniform use of survey, written instructions have been added to the questionnaire. Followed by pilot test in 40 subjects, the survey was administered face-to-face in December 2014. To investigate how perception shapes behavior, we compared perception scores in those who expressed willingness to participate and those who did not. Remarkably higher percentage of responders stated that they have heard of clinical research, and knew someone who participated (both, P < 0.001) compared to India. Yet, the percentage of responders expressed willingness to participate was 39.3%, a significantly lower rate than the result of the India (58.9% vs. 39.3%, P < 0.001). Treatment benefit was the single most influential reason for participation, followed by financial gain. Concern about safety was the main reason for refusal, succeeded by fear and lack of trust. Public awareness and educational programs addressing these negative perceptions and lack of knowledge will be effective in enhancing public engaged in clinical research.

No MeSH data available.