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Dihydroxynaphthalene-based mimicry of fungal melanogenesis for multifunctional coatings.

Jeon JR, Le TT, Chang YS - Microb Biotechnol (2016)

Bottom Line: This product, termed poly(2,7-DHN), was successfully deposited onto a wide variety of solid surfaces, including metals, polymeric materials, ceramics, biosurfaces and mineral complexes.The melanin-like polymerization could be used to co-immobilize other organic molecules, forming functional surfaces.Moreover, the novel physicochemical properties of the poly(2,7-DHN) illuminate its potential applications as bactericidal, radical-scavenging and pollutant-sorbing agents.

View Article: PubMed Central - PubMed

Affiliation: Institute of Agriculture & Life Science, Gyeongsang National University, Jinju, 52727, Korea.

No MeSH data available.


Related in: MedlinePlus

One‐pot modification of solid surfaces through in vitro laccase‐catalysed polymerization of 2,7‐DHN.A. Photograph of dipping media before and after polymerization. Left to right: before polymerization; after polymerization.B. Left to right: stainless steel; aluminium; cellulose acetate; casted polypropylene; PET; nylon; glass; plant leaf; granite. Top to down: without dipping; with dipping.
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mbt212347-fig-0001: One‐pot modification of solid surfaces through in vitro laccase‐catalysed polymerization of 2,7‐DHN.A. Photograph of dipping media before and after polymerization. Left to right: before polymerization; after polymerization.B. Left to right: stainless steel; aluminium; cellulose acetate; casted polypropylene; PET; nylon; glass; plant leaf; granite. Top to down: without dipping; with dipping.

Mentions: The anabolic action of laccase on 1,8‐DHN in vivo is known to lead to fungal melanogenesis, as shown in Scheme 1. To test the feasibility of in vitro polymerization of DHN, we reacted purified fungal laccase with commercially available 2,7‐DHN, using acidic sodium acetate buffer to maximize the enzymatic activity. The colouration demonstrated in Fig. 1A clearly indicates that the in vitro conditions allowed for efficient catalytic oxidative polymerization of 2,7‐DHN. As previously reported (Jeon et al., 2012; Jeon and Chang, 2013b), laccase should transform the phenolic moieties of the DHN into the corresponding quinone, followed by a coupling process. The coupling results in polymerization of the DHN, with its conjugated aromatic rings contributing to the formation of a chromophore that absorbs visible light.


Dihydroxynaphthalene-based mimicry of fungal melanogenesis for multifunctional coatings.

Jeon JR, Le TT, Chang YS - Microb Biotechnol (2016)

One‐pot modification of solid surfaces through in vitro laccase‐catalysed polymerization of 2,7‐DHN.A. Photograph of dipping media before and after polymerization. Left to right: before polymerization; after polymerization.B. Left to right: stainless steel; aluminium; cellulose acetate; casted polypropylene; PET; nylon; glass; plant leaf; granite. Top to down: without dipping; with dipping.
© Copyright Policy - creativeCommonsBy
Related In: Results  -  Collection

License
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getmorefigures.php?uid=PMC4835569&req=5

mbt212347-fig-0001: One‐pot modification of solid surfaces through in vitro laccase‐catalysed polymerization of 2,7‐DHN.A. Photograph of dipping media before and after polymerization. Left to right: before polymerization; after polymerization.B. Left to right: stainless steel; aluminium; cellulose acetate; casted polypropylene; PET; nylon; glass; plant leaf; granite. Top to down: without dipping; with dipping.
Mentions: The anabolic action of laccase on 1,8‐DHN in vivo is known to lead to fungal melanogenesis, as shown in Scheme 1. To test the feasibility of in vitro polymerization of DHN, we reacted purified fungal laccase with commercially available 2,7‐DHN, using acidic sodium acetate buffer to maximize the enzymatic activity. The colouration demonstrated in Fig. 1A clearly indicates that the in vitro conditions allowed for efficient catalytic oxidative polymerization of 2,7‐DHN. As previously reported (Jeon et al., 2012; Jeon and Chang, 2013b), laccase should transform the phenolic moieties of the DHN into the corresponding quinone, followed by a coupling process. The coupling results in polymerization of the DHN, with its conjugated aromatic rings contributing to the formation of a chromophore that absorbs visible light.

Bottom Line: This product, termed poly(2,7-DHN), was successfully deposited onto a wide variety of solid surfaces, including metals, polymeric materials, ceramics, biosurfaces and mineral complexes.The melanin-like polymerization could be used to co-immobilize other organic molecules, forming functional surfaces.Moreover, the novel physicochemical properties of the poly(2,7-DHN) illuminate its potential applications as bactericidal, radical-scavenging and pollutant-sorbing agents.

View Article: PubMed Central - PubMed

Affiliation: Institute of Agriculture & Life Science, Gyeongsang National University, Jinju, 52727, Korea.

No MeSH data available.


Related in: MedlinePlus