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Clinical outcomes of two types of cages used in transforaminal lumbar interbody fusion for the treatment of degenerative lumbar diseases: n-HA/PA66 cages versus PEEK cages.

Deng QX, Ou YS, Zhu Y, Zhao ZH, Liu B, Huang Q, Du X, Jiang DM - J Mater Sci Mater Med (2016)

Bottom Line: The intervertebral space height and segmental angle were also measured to estimate the radiological changes.There was no significant difference between the two groups regarding clinical and radiological results.The study indicated that both n-HA/PA66 and PEEK cages could promote effective clinical and radiographic outcomes when used to treat degenerative lumbar diseases.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, YouYi Road 1#, YuZhong District, Chongqing, 400016, People's Republic of China.

ABSTRACT
This study reports the clinical effects of nano-hydroxyapatite/polyamide66 cages (n-HA/PA66 cages) and compares the clinical outcomes between n-HA/PA66 and polyetheretherketone cages (PEEK cages) for application in transforaminal lumbar interbody fusion (TLIF). A retrospective and case-control study involving 124 patients using n-HA/PA66 cages and 142 patients using PEEK cages was conducted. All patients underwent TLIF and had an average of 2-years of follow-up. The Oswestry Disability Index and Visual Analog Scale were selected to assess the pain of low back and leg, as well as neurological status. The intervertebral space height and segmental angle were also measured to estimate the radiological changes. At the 1-year and final follow-ups, the fusion and subsidence rates were evaluated. There was no significant difference between the two groups regarding clinical and radiological results. At the final follow-up, the bony fusion rate was 92.45 and 91.57 % for the n-HA/PA66 and PEEK groups, respectively, and the subsidence rate was 7.55 and 8.99 %, respectively. The study indicated that both n-HA/PA66 and PEEK cages could promote effective clinical and radiographic outcomes when used to treat degenerative lumbar diseases. The high fusion and low subsidence rates revealed that n-HA/PA66 cages could be an alternative ideal choice as the same to PEEK cages for lumbar reconstruction after TLIF.

No MeSH data available.


A 58-year-old male who underwent 2-level TLIF with PEEK cages for lumbar reconstruction. The preoperative radiograph (a). The 1-week postoperative and 3-month and 6-month follow-up radiographs (b, c, d). The CT or 3D-CT scan (e, f, g, h, i) shows that the autogenous bone granules fill the cages and achieve bony fusion with adjacent endplates by the 12-month follow-up. A lateral radiograph (j) at the final follow-up shows satisfactory bony fusion and no obvious migration, radiolucent gap or subsidence
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Fig5: A 58-year-old male who underwent 2-level TLIF with PEEK cages for lumbar reconstruction. The preoperative radiograph (a). The 1-week postoperative and 3-month and 6-month follow-up radiographs (b, c, d). The CT or 3D-CT scan (e, f, g, h, i) shows that the autogenous bone granules fill the cages and achieve bony fusion with adjacent endplates by the 12-month follow-up. A lateral radiograph (j) at the final follow-up shows satisfactory bony fusion and no obvious migration, radiolucent gap or subsidence

Mentions: A total of 266 patients with an average 24.24 ± 8.97 months of follow-up (range 12–47 months) were included in this study. Of these, 124 patients underwent TLIF with an n-HA/PA66 cage (Fig. 4) and 142 patients underwent TLIF with a PEEK cage (Fig. 5). The demographics of the patients were shown in Table 1. No significant differences were detected in gender, age, course of disease, surgery time, blood loss, or perioperative complications between the n-HA/PA66 and PEEK cage groups.Fig. 4


Clinical outcomes of two types of cages used in transforaminal lumbar interbody fusion for the treatment of degenerative lumbar diseases: n-HA/PA66 cages versus PEEK cages.

Deng QX, Ou YS, Zhu Y, Zhao ZH, Liu B, Huang Q, Du X, Jiang DM - J Mater Sci Mater Med (2016)

A 58-year-old male who underwent 2-level TLIF with PEEK cages for lumbar reconstruction. The preoperative radiograph (a). The 1-week postoperative and 3-month and 6-month follow-up radiographs (b, c, d). The CT or 3D-CT scan (e, f, g, h, i) shows that the autogenous bone granules fill the cages and achieve bony fusion with adjacent endplates by the 12-month follow-up. A lateral radiograph (j) at the final follow-up shows satisfactory bony fusion and no obvious migration, radiolucent gap or subsidence
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4835513&req=5

Fig5: A 58-year-old male who underwent 2-level TLIF with PEEK cages for lumbar reconstruction. The preoperative radiograph (a). The 1-week postoperative and 3-month and 6-month follow-up radiographs (b, c, d). The CT or 3D-CT scan (e, f, g, h, i) shows that the autogenous bone granules fill the cages and achieve bony fusion with adjacent endplates by the 12-month follow-up. A lateral radiograph (j) at the final follow-up shows satisfactory bony fusion and no obvious migration, radiolucent gap or subsidence
Mentions: A total of 266 patients with an average 24.24 ± 8.97 months of follow-up (range 12–47 months) were included in this study. Of these, 124 patients underwent TLIF with an n-HA/PA66 cage (Fig. 4) and 142 patients underwent TLIF with a PEEK cage (Fig. 5). The demographics of the patients were shown in Table 1. No significant differences were detected in gender, age, course of disease, surgery time, blood loss, or perioperative complications between the n-HA/PA66 and PEEK cage groups.Fig. 4

Bottom Line: The intervertebral space height and segmental angle were also measured to estimate the radiological changes.There was no significant difference between the two groups regarding clinical and radiological results.The study indicated that both n-HA/PA66 and PEEK cages could promote effective clinical and radiographic outcomes when used to treat degenerative lumbar diseases.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, YouYi Road 1#, YuZhong District, Chongqing, 400016, People's Republic of China.

ABSTRACT
This study reports the clinical effects of nano-hydroxyapatite/polyamide66 cages (n-HA/PA66 cages) and compares the clinical outcomes between n-HA/PA66 and polyetheretherketone cages (PEEK cages) for application in transforaminal lumbar interbody fusion (TLIF). A retrospective and case-control study involving 124 patients using n-HA/PA66 cages and 142 patients using PEEK cages was conducted. All patients underwent TLIF and had an average of 2-years of follow-up. The Oswestry Disability Index and Visual Analog Scale were selected to assess the pain of low back and leg, as well as neurological status. The intervertebral space height and segmental angle were also measured to estimate the radiological changes. At the 1-year and final follow-ups, the fusion and subsidence rates were evaluated. There was no significant difference between the two groups regarding clinical and radiological results. At the final follow-up, the bony fusion rate was 92.45 and 91.57 % for the n-HA/PA66 and PEEK groups, respectively, and the subsidence rate was 7.55 and 8.99 %, respectively. The study indicated that both n-HA/PA66 and PEEK cages could promote effective clinical and radiographic outcomes when used to treat degenerative lumbar diseases. The high fusion and low subsidence rates revealed that n-HA/PA66 cages could be an alternative ideal choice as the same to PEEK cages for lumbar reconstruction after TLIF.

No MeSH data available.