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Dioctophyma renale (Goeze, 1782) Infection in a Domestic Dog from Hamedan, Western Iran.

Zolhavarieh SM, Norian A, Yavari M - Iran J Parasitol (2016 Jan-Mar)

Bottom Line: Dioctophyma renale infection is found in a wide range of mammalian species, typically in temperate areas of the world.We conclude that dioctophymosis can be found in cold and or relatively dry area.Moreover, the results showed that the worm was not affected with common anthelmintic drugs.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Clinical Sciences, Faculty of Veterinary Science, Bu-Ali Sina University, Hamedan, Iran.

ABSTRACT
Dioctophyma renale infection is found in a wide range of mammalian species, typically in temperate areas of the world. Here, we report for the first time, the parasitism of a domestic dog by D. renale in Hamedan, Iran, a mountainous cold region, lacking significant amounts of rainfall, high humidity and temperature. A 2.5 yr old male mixed breed dog was presented with a two months history of progressive hematuria and muscle weakness. Complete blood count and serum biochemistry were performed with results indicating impaired renal function. Urinalysis, showed hematuria as well as parasitic eggs, suggestive of D. renale infection. Urinary system ultrasonography revealed a hypoecogenic tubular structure in the right kidney. The animal was treated with fenbendazole (45 mg/kg, PO, QD - five days) and ivermectin (0.02 mg/kg, SC, single dose). One week later, repeated laboratory examination confirmed presence of at least one alive worm in the affected kidney. A unilateral nephrectomy was performed; one female (60 × 5 cm) and one male (30 × 3.8 cm) live worm were taken out of the extremely thin walled right kidney. One month later, due to failure of the remained kidney and poor condition, the patient deceased. We conclude that dioctophymosis can be found in cold and or relatively dry area. Moreover, the results showed that the worm was not affected with common anthelmintic drugs.

No MeSH data available.


Related in: MedlinePlus

The parasitic eggs were compatible with D. renale morphologically
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Related In: Results  -  Collection


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Figure 1: The parasitic eggs were compatible with D. renale morphologically

Mentions: During the clinical evaluation, the animal presented mild dehydration, hyperemic mucous membranes, and weakness. There was no elevation of body temperature. Urinalysis, complete blood count (CBC), and serum biochemistry were performed. Results showed leukocytosis with left shift neutrophlia, anisocytosis and microcytosis. In addition, the animal’s renal function was completely disrupted with serum creatinine values of 4.6 mg/dL (reference value: 0.8–1.8 mg/dL), serum urea of 58 mg/dL (reference value: 15–40 mg/dL), and severe hematuria (Table 1). Microscopic examination of urine sample showed parasitic eggs morphologically compatible with D. renale (Fig. 1). The patient received medical treatment (Fenbendazole 45 mg/kg, PO, sid, for five days and Ivermectin 0.02 mg/kg, SC, single dose).


Dioctophyma renale (Goeze, 1782) Infection in a Domestic Dog from Hamedan, Western Iran.

Zolhavarieh SM, Norian A, Yavari M - Iran J Parasitol (2016 Jan-Mar)

The parasitic eggs were compatible with D. renale morphologically
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4835464&req=5

Figure 1: The parasitic eggs were compatible with D. renale morphologically
Mentions: During the clinical evaluation, the animal presented mild dehydration, hyperemic mucous membranes, and weakness. There was no elevation of body temperature. Urinalysis, complete blood count (CBC), and serum biochemistry were performed. Results showed leukocytosis with left shift neutrophlia, anisocytosis and microcytosis. In addition, the animal’s renal function was completely disrupted with serum creatinine values of 4.6 mg/dL (reference value: 0.8–1.8 mg/dL), serum urea of 58 mg/dL (reference value: 15–40 mg/dL), and severe hematuria (Table 1). Microscopic examination of urine sample showed parasitic eggs morphologically compatible with D. renale (Fig. 1). The patient received medical treatment (Fenbendazole 45 mg/kg, PO, sid, for five days and Ivermectin 0.02 mg/kg, SC, single dose).

Bottom Line: Dioctophyma renale infection is found in a wide range of mammalian species, typically in temperate areas of the world.We conclude that dioctophymosis can be found in cold and or relatively dry area.Moreover, the results showed that the worm was not affected with common anthelmintic drugs.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Clinical Sciences, Faculty of Veterinary Science, Bu-Ali Sina University, Hamedan, Iran.

ABSTRACT
Dioctophyma renale infection is found in a wide range of mammalian species, typically in temperate areas of the world. Here, we report for the first time, the parasitism of a domestic dog by D. renale in Hamedan, Iran, a mountainous cold region, lacking significant amounts of rainfall, high humidity and temperature. A 2.5 yr old male mixed breed dog was presented with a two months history of progressive hematuria and muscle weakness. Complete blood count and serum biochemistry were performed with results indicating impaired renal function. Urinalysis, showed hematuria as well as parasitic eggs, suggestive of D. renale infection. Urinary system ultrasonography revealed a hypoecogenic tubular structure in the right kidney. The animal was treated with fenbendazole (45 mg/kg, PO, QD - five days) and ivermectin (0.02 mg/kg, SC, single dose). One week later, repeated laboratory examination confirmed presence of at least one alive worm in the affected kidney. A unilateral nephrectomy was performed; one female (60 × 5 cm) and one male (30 × 3.8 cm) live worm were taken out of the extremely thin walled right kidney. One month later, due to failure of the remained kidney and poor condition, the patient deceased. We conclude that dioctophymosis can be found in cold and or relatively dry area. Moreover, the results showed that the worm was not affected with common anthelmintic drugs.

No MeSH data available.


Related in: MedlinePlus