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Severe Diarrhea Due To Cystoisospora belli Infection in an HTLV-1 Woman.

Shafiei R, Najjari M, Kargar Kheirabad A, Hatam G - Iran J Parasitol (2016 Jan-Mar)

Bottom Line: Serologic testing was negative for HIV but she showed positivity for HTLV-1 infection.Treatment with TMP/SMX led to improvement of her diarrhea but she died after one year due to malabsorption syndrome.Adequate detection of C. belli diarrhea in immunocompromise patients of HTLV1 in endemic area can be cured by TMP/SMX.

View Article: PubMed Central - PubMed

Affiliation: Vector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran; Dept. of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

ABSTRACT
Cystoisospora belli, formerly Isospora belli, as an opportunistic infection agent, is seen in immunocompromised patients like HTLV-1. We describe here cystoisosporiasis in an HTLV1 Iranian female in Mashhad, northwestern Iran in 2012 who presented with a debilitating diarrheal illness and great weight loss. C. belli was detected in her stool by modified acid-fast staining and then by molecular detection. Serologic testing was negative for HIV but she showed positivity for HTLV-1 infection. Treatment with TMP/SMX led to improvement of her diarrhea but she died after one year due to malabsorption syndrome. Adequate detection of C. belli diarrhea in immunocompromise patients of HTLV1 in endemic area can be cured by TMP/SMX.

No MeSH data available.


Related in: MedlinePlus

Cystoisospora belli oocyst in a direct wet mount smear after staining with modified Ziehl-Neelsen before concentration (Original)
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Figure 1: Cystoisospora belli oocyst in a direct wet mount smear after staining with modified Ziehl-Neelsen before concentration (Original)

Mentions: Parasitology investigation of diarrheic stool sample at the first run was reported to be negative. Two days later, however, numerous oocysts of C. belli were clearly and frequently seen in a second sample using the Willis flotation method in direct smear and the modified Ziehl-Neelsen staining (Fig. 1). No other parasites or pathogenic bacteria were found in the stool sample.


Severe Diarrhea Due To Cystoisospora belli Infection in an HTLV-1 Woman.

Shafiei R, Najjari M, Kargar Kheirabad A, Hatam G - Iran J Parasitol (2016 Jan-Mar)

Cystoisospora belli oocyst in a direct wet mount smear after staining with modified Ziehl-Neelsen before concentration (Original)
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4835462&req=5

Figure 1: Cystoisospora belli oocyst in a direct wet mount smear after staining with modified Ziehl-Neelsen before concentration (Original)
Mentions: Parasitology investigation of diarrheic stool sample at the first run was reported to be negative. Two days later, however, numerous oocysts of C. belli were clearly and frequently seen in a second sample using the Willis flotation method in direct smear and the modified Ziehl-Neelsen staining (Fig. 1). No other parasites or pathogenic bacteria were found in the stool sample.

Bottom Line: Serologic testing was negative for HIV but she showed positivity for HTLV-1 infection.Treatment with TMP/SMX led to improvement of her diarrhea but she died after one year due to malabsorption syndrome.Adequate detection of C. belli diarrhea in immunocompromise patients of HTLV1 in endemic area can be cured by TMP/SMX.

View Article: PubMed Central - PubMed

Affiliation: Vector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran; Dept. of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

ABSTRACT
Cystoisospora belli, formerly Isospora belli, as an opportunistic infection agent, is seen in immunocompromised patients like HTLV-1. We describe here cystoisosporiasis in an HTLV1 Iranian female in Mashhad, northwestern Iran in 2012 who presented with a debilitating diarrheal illness and great weight loss. C. belli was detected in her stool by modified acid-fast staining and then by molecular detection. Serologic testing was negative for HIV but she showed positivity for HTLV-1 infection. Treatment with TMP/SMX led to improvement of her diarrhea but she died after one year due to malabsorption syndrome. Adequate detection of C. belli diarrhea in immunocompromise patients of HTLV1 in endemic area can be cured by TMP/SMX.

No MeSH data available.


Related in: MedlinePlus