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The Research and Applications of Quantum Dots as Nano-Carriers for Targeted Drug Delivery and Cancer Therapy.

Zhao MX, Zhu BJ - Nanoscale Res Lett (2016)

Bottom Line: In addition, QD nano-carrier systems for drugs can improve stability of drugs, lengthen circulation time in vivo, enhance targeted absorption, and improve the distribution and metabolism process of drugs in organization.So, the development of QD nano-carriers for drugs has become a hotspot in the fields of nano-drug research in recent years.In this paper, we review the advantages and applications of the QD nano-carriers for drugs in biological fields.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory of Natural Medicine and Immune Engineering, Henan University, Kaifeng, 475004, China. zhaomeixia2011@henu.edu.cn.

ABSTRACT
Quantum dots (QDs), nano-carriers for drugs, can help realize the targeting of drugs, and improve the bioavailability of drugs in biological fields. And, a QD nano-carrier system for drugs has the potential to realize early detection, monitoring, and localized treatments of specific disease sites. In addition, QD nano-carrier systems for drugs can improve stability of drugs, lengthen circulation time in vivo, enhance targeted absorption, and improve the distribution and metabolism process of drugs in organization. So, the development of QD nano-carriers for drugs has become a hotspot in the fields of nano-drug research in recent years. In this paper, we review the advantages and applications of the QD nano-carriers for drugs in biological fields.

No MeSH data available.


Related in: MedlinePlus

Schematic of the preparation of QD-PEG-ADM and the mechanism of this system for drug release [45]
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Fig8: Schematic of the preparation of QD-PEG-ADM and the mechanism of this system for drug release [45]

Mentions: An effective and facile FRET-based QD-PEG-Dox drug delivery system (DDS) has been used for real-time monitoring of the release of loaded drugs (ADM) in situ (Fig. 8) [45]. An outstanding correlation between the FRET signal and drug release in different pH environments has been applied to real-time detection of (Dox). The methods of ratiometric and time-resolved fluorometry are practical for real-time monitoring of drug release in tumor cells. It would promote the development of versatile DDS, and offering a sensitive and efficient method to monitor in real-time the release in situ of drugs, especially in physiological microenvironments.Fig. 8


The Research and Applications of Quantum Dots as Nano-Carriers for Targeted Drug Delivery and Cancer Therapy.

Zhao MX, Zhu BJ - Nanoscale Res Lett (2016)

Schematic of the preparation of QD-PEG-ADM and the mechanism of this system for drug release [45]
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4835414&req=5

Fig8: Schematic of the preparation of QD-PEG-ADM and the mechanism of this system for drug release [45]
Mentions: An effective and facile FRET-based QD-PEG-Dox drug delivery system (DDS) has been used for real-time monitoring of the release of loaded drugs (ADM) in situ (Fig. 8) [45]. An outstanding correlation between the FRET signal and drug release in different pH environments has been applied to real-time detection of (Dox). The methods of ratiometric and time-resolved fluorometry are practical for real-time monitoring of drug release in tumor cells. It would promote the development of versatile DDS, and offering a sensitive and efficient method to monitor in real-time the release in situ of drugs, especially in physiological microenvironments.Fig. 8

Bottom Line: In addition, QD nano-carrier systems for drugs can improve stability of drugs, lengthen circulation time in vivo, enhance targeted absorption, and improve the distribution and metabolism process of drugs in organization.So, the development of QD nano-carriers for drugs has become a hotspot in the fields of nano-drug research in recent years.In this paper, we review the advantages and applications of the QD nano-carriers for drugs in biological fields.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory of Natural Medicine and Immune Engineering, Henan University, Kaifeng, 475004, China. zhaomeixia2011@henu.edu.cn.

ABSTRACT
Quantum dots (QDs), nano-carriers for drugs, can help realize the targeting of drugs, and improve the bioavailability of drugs in biological fields. And, a QD nano-carrier system for drugs has the potential to realize early detection, monitoring, and localized treatments of specific disease sites. In addition, QD nano-carrier systems for drugs can improve stability of drugs, lengthen circulation time in vivo, enhance targeted absorption, and improve the distribution and metabolism process of drugs in organization. So, the development of QD nano-carriers for drugs has become a hotspot in the fields of nano-drug research in recent years. In this paper, we review the advantages and applications of the QD nano-carriers for drugs in biological fields.

No MeSH data available.


Related in: MedlinePlus