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Endovascular treatment versus medical care alone for ischaemic stroke: systematic review and meta-analysis.

Rodrigues FB, Neves JB, Caldeira D, Ferro JM, Ferreira JJ, Costa J - BMJ (2016)

Bottom Line: Systematic review and meta-analysis.Heterogeneity was high among studies.Subgroup analysis of these seven studies yielded a risk ratio of 1.56 (95% confidence interval 1.38 to 1.75) for good functional outcomes and 0.86 (0.69 to 1.06) for mortality, without heterogeneity among the results of the studies.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, University of Lisbon, Av Prof Egas Moniz 1649-035, Lisbon, Portugal Clinical Pharmacology Unit, Instituto de Medicina Molecular, Lisbon, Portugal Department of Medicine, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Portugal filipebrodrigues@gmail.com.

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Fig 4 Forest plot for mortality at 90 days, including subgroup analysis by year of study publication. AIMT=adjunctive intra-arterial mechanical thrombectomy
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f4: Fig 4 Forest plot for mortality at 90 days, including subgroup analysis by year of study publication. AIMT=adjunctive intra-arterial mechanical thrombectomy

Mentions: At 90 days, 482 out of 2880 participants (16.7%) died, without differences between arms in all cause mortality (risk ratio 0.90, 95% confidence interval 0.76 to 1.06; I2=0%, P=0.52; fig 4). Furthermore, the results did not differ between trials published in 2013 and 2015 (P=0.48). Sensitivity analysis excluding THRACE and THERAPY from the pooled risk ratio for 2015 trials yielded similar results (0.87, 0.68 to 1.11; I2=0%, P=0.43).


Endovascular treatment versus medical care alone for ischaemic stroke: systematic review and meta-analysis.

Rodrigues FB, Neves JB, Caldeira D, Ferro JM, Ferreira JJ, Costa J - BMJ (2016)

Fig 4 Forest plot for mortality at 90 days, including subgroup analysis by year of study publication. AIMT=adjunctive intra-arterial mechanical thrombectomy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4834754&req=5

f4: Fig 4 Forest plot for mortality at 90 days, including subgroup analysis by year of study publication. AIMT=adjunctive intra-arterial mechanical thrombectomy
Mentions: At 90 days, 482 out of 2880 participants (16.7%) died, without differences between arms in all cause mortality (risk ratio 0.90, 95% confidence interval 0.76 to 1.06; I2=0%, P=0.52; fig 4). Furthermore, the results did not differ between trials published in 2013 and 2015 (P=0.48). Sensitivity analysis excluding THRACE and THERAPY from the pooled risk ratio for 2015 trials yielded similar results (0.87, 0.68 to 1.11; I2=0%, P=0.43).

Bottom Line: Systematic review and meta-analysis.Heterogeneity was high among studies.Subgroup analysis of these seven studies yielded a risk ratio of 1.56 (95% confidence interval 1.38 to 1.75) for good functional outcomes and 0.86 (0.69 to 1.06) for mortality, without heterogeneity among the results of the studies.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, University of Lisbon, Av Prof Egas Moniz 1649-035, Lisbon, Portugal Clinical Pharmacology Unit, Instituto de Medicina Molecular, Lisbon, Portugal Department of Medicine, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Portugal filipebrodrigues@gmail.com.

Show MeSH
Related in: MedlinePlus