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Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non-adherent to CPAP.

Gjerde K, Lehmann S, Berge ME, Johansson AK, Johansson A - J Oral Rehabil (2015)

Bottom Line: A successful OA treatment outcome was based on polygraphy at the follow-up and divided into three groups: 1 = AHI <5; 2 = 5 ≤ AHI <10 and >50% reduction in baseline AHI; and 3. >50% reduction in baseline AHI.If there was a ≤ 50% reduction in baseline AHI at the follow-up, the treatment was considered as a failure.There was no significant difference in success rates between patients in the moderate and severe categories (69% and 77%, respectively).

View Article: PubMed Central - PubMed

Affiliation: Department of Thoracic Medicine, Center for Sleep Medicine, Haukeland University Hospital, Bergen, Norway.

No MeSH data available.


Related in: MedlinePlus

Receiver operating characteristic (ROC) curve for SpO2 nadir and for the full model including all variables in the regression analysis.
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joor12376-fig-0003: Receiver operating characteristic (ROC) curve for SpO2 nadir and for the full model including all variables in the regression analysis.

Mentions: The outcome on the univariate evaluation of factors potentially predicting treatment failure is shown in Table 5, and the results from the logistic regression analyses are presented in Table 6. In the unadjusted analyses, all selected independent variables, except gender and SpO2 <90%, were significantly correlated to the success criteria applied, while in the fully adjusted analyses none of the variables predicted treatment failure/success. When applying the forward conditional method, SpO2 nadir turned out to be significant (OR = 0·36, p = 0·001) (Table 6); Nagelkerke R2 was 0·18 and the sensitivity (correctly classified successfully treated) and specificity (correctly classified failures) was 37% and 93%, respectively. The predicted probability for all variables and for SpO2 nadir is illustrated by the receiver operating characteristic (ROC) curve where the area under the curve (AUC) was 0·66 for SpO2 nadir while AUC for all the variables combined was 0·79 (Fig. 3).


Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non-adherent to CPAP.

Gjerde K, Lehmann S, Berge ME, Johansson AK, Johansson A - J Oral Rehabil (2015)

Receiver operating characteristic (ROC) curve for SpO2 nadir and for the full model including all variables in the regression analysis.
© Copyright Policy - creativeCommonsBy-nc
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4834725&req=5

joor12376-fig-0003: Receiver operating characteristic (ROC) curve for SpO2 nadir and for the full model including all variables in the regression analysis.
Mentions: The outcome on the univariate evaluation of factors potentially predicting treatment failure is shown in Table 5, and the results from the logistic regression analyses are presented in Table 6. In the unadjusted analyses, all selected independent variables, except gender and SpO2 <90%, were significantly correlated to the success criteria applied, while in the fully adjusted analyses none of the variables predicted treatment failure/success. When applying the forward conditional method, SpO2 nadir turned out to be significant (OR = 0·36, p = 0·001) (Table 6); Nagelkerke R2 was 0·18 and the sensitivity (correctly classified successfully treated) and specificity (correctly classified failures) was 37% and 93%, respectively. The predicted probability for all variables and for SpO2 nadir is illustrated by the receiver operating characteristic (ROC) curve where the area under the curve (AUC) was 0·66 for SpO2 nadir while AUC for all the variables combined was 0·79 (Fig. 3).

Bottom Line: A successful OA treatment outcome was based on polygraphy at the follow-up and divided into three groups: 1 = AHI <5; 2 = 5 ≤ AHI <10 and >50% reduction in baseline AHI; and 3. >50% reduction in baseline AHI.If there was a ≤ 50% reduction in baseline AHI at the follow-up, the treatment was considered as a failure.There was no significant difference in success rates between patients in the moderate and severe categories (69% and 77%, respectively).

View Article: PubMed Central - PubMed

Affiliation: Department of Thoracic Medicine, Center for Sleep Medicine, Haukeland University Hospital, Bergen, Norway.

No MeSH data available.


Related in: MedlinePlus