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Machine-Assisted Organic Synthesis.

Ley SV, Fitzpatrick DE, Myers RM, Battilocchio C, Ingham RJ - Angew. Chem. Int. Ed. Engl. (2015)

Bottom Line: In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors.Additional technologies have been developed to facilitate more specialized reaction techniques such as electrochemical and photochemical methods.All of these areas create both opportunities and challenges during adoption as enabling technologies.

View Article: PubMed Central - PubMed

Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). svl1000@cam.ac.uk.

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Related in: MedlinePlus

Encapsulated glutaminase has been used during the synthesis of theanine. Increased temperature control of such a reactor system led to higher than normal enzyme activity.
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Related In: Results  -  Collection


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fig16: Encapsulated glutaminase has been used during the synthesis of theanine. Increased temperature control of such a reactor system led to higher than normal enzyme activity.

Mentions: A glutaminase‐based encapsulated enzyme system proved most effective during the synthesis of theanine (a simple amino acid; Figure 16). The high enzyme activity was attributed to the accuracy of the local temperature control of the microreactor compared to batch‐mode processing.73


Machine-Assisted Organic Synthesis.

Ley SV, Fitzpatrick DE, Myers RM, Battilocchio C, Ingham RJ - Angew. Chem. Int. Ed. Engl. (2015)

Encapsulated glutaminase has been used during the synthesis of theanine. Increased temperature control of such a reactor system led to higher than normal enzyme activity.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4834626&req=5

fig16: Encapsulated glutaminase has been used during the synthesis of theanine. Increased temperature control of such a reactor system led to higher than normal enzyme activity.
Mentions: A glutaminase‐based encapsulated enzyme system proved most effective during the synthesis of theanine (a simple amino acid; Figure 16). The high enzyme activity was attributed to the accuracy of the local temperature control of the microreactor compared to batch‐mode processing.73

Bottom Line: In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors.Additional technologies have been developed to facilitate more specialized reaction techniques such as electrochemical and photochemical methods.All of these areas create both opportunities and challenges during adoption as enabling technologies.

View Article: PubMed Central - PubMed

Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). svl1000@cam.ac.uk.

Show MeSH
Related in: MedlinePlus