Machine-Assisted Organic Synthesis.
Bottom Line: In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors.Additional technologies have been developed to facilitate more specialized reaction techniques such as electrochemical and photochemical methods.All of these areas create both opportunities and challenges during adoption as enabling technologies.
Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). email@example.com.Show MeSH
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Mentions: In another study, the same group demonstrated a multicolumn reactor concept which enabled researchers to switch products formed in real‐time by changing the column conditions.14 Two packed reactor columns were placed in series, one containing copper chromate and the other Pd/C, each with its own H2 supply. A feed stream containing furfural (Figure 3 a) was mixed with CO2 before entering the first column. It was found that a range of products could be formed (Figure 3 b) in relatively high yields (>80 %) by adjusting the column temperatures and the amount of H2 supplied to each column in turn.
Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). firstname.lastname@example.org.