Machine-Assisted Organic Synthesis.
Bottom Line: In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors.Additional technologies have been developed to facilitate more specialized reaction techniques such as electrochemical and photochemical methods.All of these areas create both opportunities and challenges during adoption as enabling technologies.
Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). firstname.lastname@example.org.Show MeSH
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Mentions: Another example of both reactor design and exemplification through application include a direct continuous‐flow electrochemical procedure for benzylic methoxylation (4‐electron product) and oxidation (6‐electron product) by using a modular plate‐based microfluidic cell (Figure 22).93 This example is interesting, since it demonstrates how electrolysis at constant current, specifically in flow, enables control or, at best, modulation of substrate over‐oxidation by removal of the desired products.
Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). email@example.com.