Machine-Assisted Organic Synthesis.
Bottom Line: In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors.Additional technologies have been developed to facilitate more specialized reaction techniques such as electrochemical and photochemical methods.All of these areas create both opportunities and challenges during adoption as enabling technologies.
Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). email@example.com.Show MeSH
Related in: MedlinePlus
Mentions: A recent study investigated the efficacy of five reactor designs for carrying out ene reactions with singlet oxygen. The systems tested (Figure 23) were chosen so as to give an insight into design parameters for photocatalyzed microreactors and were comprised of an immersed well reactor (batch mode), a recirculating annular reactor, and three microchip‐based reaction systems. It was found that the excellent mixing conditions and the large surface area to volume ratio inherent to the microreactor systems lead to more efficient product formation for the oxygenation of α‐pinene to pinocarvone.97
Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). firstname.lastname@example.org.