Machine-Assisted Organic Synthesis.
Bottom Line: In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors.Additional technologies have been developed to facilitate more specialized reaction techniques such as electrochemical and photochemical methods.All of these areas create both opportunities and challenges during adoption as enabling technologies.
Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). firstname.lastname@example.org.Show MeSH
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Mentions: An alternative to microwave methods is inductive heating, which is an effective method for heating reactions to high temperatures. Kirschning and co‐workers have reported the use of superparamagnetic nanoparticles coated with silica gel and steel beads as efficient materials to use in a fix‐bed flow reactor to rapidly achieve high temperatures under exposure to an inductive magnetic field (Figure 11).53
Affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK). email@example.com.