A simple and general strategy for generating frequency-anticorrelated photon pairs.
Bottom Line:
To reduce the required flux, a promising solution is to use highly frequency-anticorrelated photon pairs, which are known to induce two-photon transitions much more efficiently.It is shown quantitatively that this strategy can generate highly frequency-anticorrelated photon pairs which can dramatically enhance two-photon excitation efficiency.We believe the proposed strategy can guide new designs for generating frequency-anticorrelated photon pairs.
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PubMed Central - PubMed
Affiliation: Department of Physics and Key Laboratory of Modern Acoustics, Nanjing University, Nanjing 210008, China.
ABSTRACT
Currently, two-photon excitation microscopy is the method of choice for imaging living cells within thick specimen. A remaining problem for this technique is the damage caused by the high photon flux in the excitation region. To reduce the required flux, a promising solution is to use highly frequency-anticorrelated photon pairs, which are known to induce two-photon transitions much more efficiently. It is still an open question what the best scheme is for generating such photon pairs. Here we propose one simple general strategy for this task. As an example, we show explicitly that this general strategy can be realized faithfully within the widely applicable coherently pumped Jaynes-Cummings model. It is shown quantitatively that this strategy can generate highly frequency-anticorrelated photon pairs which can dramatically enhance two-photon excitation efficiency. We believe the proposed strategy can guide new designs for generating frequency-anticorrelated photon pairs. No MeSH data available. Related in: MedlinePlus |
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Mentions: In this paper we propose one simple general such strategy. This strategy is to find or design the following generic scenario: an initial state A, which is otherwise stable, is coherently and weakly coupled to state B, which decays quickly through single photon-emission to state C. State C in turn decays quickly through single photon-emission to a final stable state D. More succinctly, this can be written as “”, where “” denotes a weak coherent coupling, while “→” denotes fast irreversible single-photon emission (cf. Fig. 1). This strategy is robust in the sense that, guaranteed by generally valid physical principles such as energy conservation and the time-energy uncertainty relation, the photon pairs thus generated will be frequency-anticorrelated. As an explicit example, we show that this simple strategy can be realized faithfully in the widely applicable coherently pumped Jaynes-Cummings (JC) model20. Furthermore, the wave function of the outgoing photon pair is derived analytically and it shows quantitatively that the photon pair can possess pronounced frequency-anticorrelation. Finally, through a simple modeling of the processes of two-photon excitation induced fluorescence, we show that these frequency-anticorrelated photon pairs can give a large enhancement in two-photon excitation induced fluorescence compared to uncorrelated photon pairs. Our results thus show that, the proposed simple general strategy is capable of generating highly frequency-anticorrelated photon pairs that can dramatically enhance two-photon excitation efficiency, which could be crucial for low-flux two-photon microscopy applications. |
View Article: PubMed Central - PubMed
Affiliation: Department of Physics and Key Laboratory of Modern Acoustics, Nanjing University, Nanjing 210008, China.
No MeSH data available.