Is it me? Verbal self-monitoring neural network and clinical insight in schizophrenia.
Bottom Line: Healthy participants showed higher performance accuracy and greater thalamic activity than both preserved and poor insight patient groups.Preserved insight patients showed higher activity in the putamen extending into the caudate, insula and inferior frontal gyrus, compared to poor insight patients, and in the anterior cingulate and medial frontal gyrus, compared to healthy participants.Poor insight patients did not show greater activity in any brain area compared to preserved insight patients or healthy participants.
Affiliation: Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.Show MeSH
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Mentions: Healthy participants, relative to preserved insight patients, again showed greater activity in the thalami (bilaterally) and the right posterior cingulate (Self condition). Preserved insight patients showed greater activity in the ACC and medial-middle frontal gyrus (Self condition) (Fig. 1).
Affiliation: Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.