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Preparation Methods for Improving PEEK's Bioactivity for Orthopedic and Dental Application: A Review.

Almasi D, Iqbal N, Sadeghi M, Sudin I, Abdul Kadir MR, Kamarul T - Int J Biomater (2016)

Bottom Line: There is an increased interest in the use of polyether ether ketone (PEEK) for orthopedic and dental implant applications due to its elastic modulus close to that of bone, biocompatibility, and its radiolucent properties.However, PEEK is still categorized as bioinert due to its low integration with surrounding tissues.Many studies have reported on methods to increase the bioactivity of PEEK, but there is still one-preparation method for preparing bioactive PEEK implant where the produced implant with desirable mechanical and bioactivity properties is required.

View Article: PubMed Central - PubMed

Affiliation: Department of Materials, Manufacturing and Industrial Engineering, Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia.

ABSTRACT
There is an increased interest in the use of polyether ether ketone (PEEK) for orthopedic and dental implant applications due to its elastic modulus close to that of bone, biocompatibility, and its radiolucent properties. However, PEEK is still categorized as bioinert due to its low integration with surrounding tissues. Many studies have reported on methods to increase the bioactivity of PEEK, but there is still one-preparation method for preparing bioactive PEEK implant where the produced implant with desirable mechanical and bioactivity properties is required. The aim of this review is to present the progress of the preparation methods for improvement of the bioactivity of PEEK and to discuss the strengths and weaknesses of the existing methods.

No MeSH data available.


Related in: MedlinePlus

PEEK bioinert properties and growth of soft tissue around it [30].
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fig1: PEEK bioinert properties and growth of soft tissue around it [30].

Mentions: An essential problem with most polymers, including PEEK, is their low-surface energy. This hydrophobic property of the surface can reduce cellular adhesion. The lack of response from the biological environment caused PEEK to be categorized as bioinert [28, 29]. As explained above one of the most important applications of PEEK is for orthopedic area. The bioinert properties of PEEK in the orthopedic area mean the growth of soft tissues around the PEEK implant instead of bone growth (Figure 1) [30].


Preparation Methods for Improving PEEK's Bioactivity for Orthopedic and Dental Application: A Review.

Almasi D, Iqbal N, Sadeghi M, Sudin I, Abdul Kadir MR, Kamarul T - Int J Biomater (2016)

PEEK bioinert properties and growth of soft tissue around it [30].
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4834406&req=5

fig1: PEEK bioinert properties and growth of soft tissue around it [30].
Mentions: An essential problem with most polymers, including PEEK, is their low-surface energy. This hydrophobic property of the surface can reduce cellular adhesion. The lack of response from the biological environment caused PEEK to be categorized as bioinert [28, 29]. As explained above one of the most important applications of PEEK is for orthopedic area. The bioinert properties of PEEK in the orthopedic area mean the growth of soft tissues around the PEEK implant instead of bone growth (Figure 1) [30].

Bottom Line: There is an increased interest in the use of polyether ether ketone (PEEK) for orthopedic and dental implant applications due to its elastic modulus close to that of bone, biocompatibility, and its radiolucent properties.However, PEEK is still categorized as bioinert due to its low integration with surrounding tissues.Many studies have reported on methods to increase the bioactivity of PEEK, but there is still one-preparation method for preparing bioactive PEEK implant where the produced implant with desirable mechanical and bioactivity properties is required.

View Article: PubMed Central - PubMed

Affiliation: Department of Materials, Manufacturing and Industrial Engineering, Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia.

ABSTRACT
There is an increased interest in the use of polyether ether ketone (PEEK) for orthopedic and dental implant applications due to its elastic modulus close to that of bone, biocompatibility, and its radiolucent properties. However, PEEK is still categorized as bioinert due to its low integration with surrounding tissues. Many studies have reported on methods to increase the bioactivity of PEEK, but there is still one-preparation method for preparing bioactive PEEK implant where the produced implant with desirable mechanical and bioactivity properties is required. The aim of this review is to present the progress of the preparation methods for improvement of the bioactivity of PEEK and to discuss the strengths and weaknesses of the existing methods.

No MeSH data available.


Related in: MedlinePlus