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Capillary hemangioma of the testis. A case report of a rare benign tumor.

Białek W, Rudzki S, Wronecki L - J Ultrason (2016)

Bottom Line: No abnormalities were found in any of these tests.No abnormalities were found in the patient's medical history, physical examination or ultrasound scan of the right testis.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, 1st Military Hospital, Lublin, Poland; Department of General and Transplant Surgery and Nutritional Treatment, Medical University of Lublin, Poland.

ABSTRACT
This paper presents the case of a very rare capillary hemangioma of the testis in a 23-year-old patient. Physical examination revealed a tumor located in the upper pole of the left testis, which was suspected of being malignant due to its significantly increased density and irregular contours. Blood levels of the following tumor markers were determined: alpha-fetoprotein, human chorionic gonadotropin and lactate dehydrogenase. No abnormalities were found in any of these tests. A gray-scale ultrasound scan of the scrotum revealed a lesion located in the upper pole of the left testis, 24 mm in diameter with slightly decreased echogenicity and irregular contours, which suggested infiltration of the tunica albuginea of the testis. Color and power Doppler scans demonstrated a dense network of blood vessels and increased blood flow in the lesion described. In addition, 3D ultrasound scan images were obtained, which allowed for a thorough determination of the topography of the lesion. No abnormalities were found in the patient's medical history, physical examination or ultrasound scan of the right testis. Taking into account the suspected malignancy with signs of infiltration of the tunica albuginea of the upper pole of the testis a decision was made to remove the left testis together with the spermatic cord using the inguinal approach. A histopathological examination of the whole specimen revealed a multifocal capillary hemangioma of the testis, signs of testicular fibrosis and significant atrophy of the spermatogenic epithelium of the seminiferous tubules. Immunohistochemistry: CD31 (+), CD34 (+), FVIII (-), vimentin (+), CK MNF116 (-), mesothelial cells (-), calretinin (-), MIB-1 = 8.4%. The tumor described is one of the few benign lesions originating from the tissues of the testis for which partial resection of the organ may be considered. Intraoperative histopathological examination and resection of the lesion with the preservation of a healthy tissue margin may be considered in patients with a single testis in whom the tumor is found to have a very rich vascular network and the levels of tumor markers are normal.

No MeSH data available.


Related in: MedlinePlus

Capillary hemangioma of the testis: A. benign tumor composed of a proliferation of capillary-size vessels in the testis parenchyma (hematoxylin and eosin, original magnification × 10); B. numerous capillary-size vessels lined by endothelial cells without anaplastic features (hematoxylin and eosin, original magnification × 40); C. Endothelial cells showing prominent immunostaining for CD31 (original magnification × 10); D. Endothelial cells showing prominent immunostaining for CD34 (original magnification × 20)
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Figure 0008: Capillary hemangioma of the testis: A. benign tumor composed of a proliferation of capillary-size vessels in the testis parenchyma (hematoxylin and eosin, original magnification × 10); B. numerous capillary-size vessels lined by endothelial cells without anaplastic features (hematoxylin and eosin, original magnification × 40); C. Endothelial cells showing prominent immunostaining for CD31 (original magnification × 10); D. Endothelial cells showing prominent immunostaining for CD34 (original magnification × 20)

Mentions: Full pathomorphological diagnosis: Haemangioma capillare multifocale testis. Fibrosis testis et atrophia epithelii spermatogenici tubulorum seminiferorum maioris gradus. Immunohistochemistry: CK MNF116 (−), FVIII (−), CD31 (+), CD34 (+), vimentin (+), mesothelial cells (−), calretinin (−), MIB-1 = 8.4% (Fig. 8).


Capillary hemangioma of the testis. A case report of a rare benign tumor.

Białek W, Rudzki S, Wronecki L - J Ultrason (2016)

Capillary hemangioma of the testis: A. benign tumor composed of a proliferation of capillary-size vessels in the testis parenchyma (hematoxylin and eosin, original magnification × 10); B. numerous capillary-size vessels lined by endothelial cells without anaplastic features (hematoxylin and eosin, original magnification × 40); C. Endothelial cells showing prominent immunostaining for CD31 (original magnification × 10); D. Endothelial cells showing prominent immunostaining for CD34 (original magnification × 20)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4834374&req=5

Figure 0008: Capillary hemangioma of the testis: A. benign tumor composed of a proliferation of capillary-size vessels in the testis parenchyma (hematoxylin and eosin, original magnification × 10); B. numerous capillary-size vessels lined by endothelial cells without anaplastic features (hematoxylin and eosin, original magnification × 40); C. Endothelial cells showing prominent immunostaining for CD31 (original magnification × 10); D. Endothelial cells showing prominent immunostaining for CD34 (original magnification × 20)
Mentions: Full pathomorphological diagnosis: Haemangioma capillare multifocale testis. Fibrosis testis et atrophia epithelii spermatogenici tubulorum seminiferorum maioris gradus. Immunohistochemistry: CK MNF116 (−), FVIII (−), CD31 (+), CD34 (+), vimentin (+), mesothelial cells (−), calretinin (−), MIB-1 = 8.4% (Fig. 8).

Bottom Line: No abnormalities were found in any of these tests.No abnormalities were found in the patient's medical history, physical examination or ultrasound scan of the right testis.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, 1st Military Hospital, Lublin, Poland; Department of General and Transplant Surgery and Nutritional Treatment, Medical University of Lublin, Poland.

ABSTRACT
This paper presents the case of a very rare capillary hemangioma of the testis in a 23-year-old patient. Physical examination revealed a tumor located in the upper pole of the left testis, which was suspected of being malignant due to its significantly increased density and irregular contours. Blood levels of the following tumor markers were determined: alpha-fetoprotein, human chorionic gonadotropin and lactate dehydrogenase. No abnormalities were found in any of these tests. A gray-scale ultrasound scan of the scrotum revealed a lesion located in the upper pole of the left testis, 24 mm in diameter with slightly decreased echogenicity and irregular contours, which suggested infiltration of the tunica albuginea of the testis. Color and power Doppler scans demonstrated a dense network of blood vessels and increased blood flow in the lesion described. In addition, 3D ultrasound scan images were obtained, which allowed for a thorough determination of the topography of the lesion. No abnormalities were found in the patient's medical history, physical examination or ultrasound scan of the right testis. Taking into account the suspected malignancy with signs of infiltration of the tunica albuginea of the upper pole of the testis a decision was made to remove the left testis together with the spermatic cord using the inguinal approach. A histopathological examination of the whole specimen revealed a multifocal capillary hemangioma of the testis, signs of testicular fibrosis and significant atrophy of the spermatogenic epithelium of the seminiferous tubules. Immunohistochemistry: CD31 (+), CD34 (+), FVIII (-), vimentin (+), CK MNF116 (-), mesothelial cells (-), calretinin (-), MIB-1 = 8.4%. The tumor described is one of the few benign lesions originating from the tissues of the testis for which partial resection of the organ may be considered. Intraoperative histopathological examination and resection of the lesion with the preservation of a healthy tissue margin may be considered in patients with a single testis in whom the tumor is found to have a very rich vascular network and the levels of tumor markers are normal.

No MeSH data available.


Related in: MedlinePlus