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Value and Efficacy of Transcranial Direct Current Stimulation in the Cognitive Rehabilitation: A Critical Review Since 2000.

Cappon D, Jahanshahi M, Bisiacchi P - Front Neurosci (2016)

Bottom Line: However, the results show a high variability between studies both in terms of the methodological approach adopted and the cognitive functions targeted.The review also focuses both on methodological issues such as technical aspects of the stimulation (electrode position and dimension; current intensity; duration of protocol) and on the inclusion of appropriate assessment tools for cognition.We conclude that more studies using common methodology are needed to gain a better understanding of the efficacy of tDCS as a new tool for rehabilitation of cognitive disorders in a range of neurological disorders.

View Article: PubMed Central - PubMed

Affiliation: Department of General Psychology, Center for Cognitive Neuroscience, University of Padova Padua, Italy.

ABSTRACT
Non-invasive brain stimulation techniques, including transcranial direct current stimulation (t-DCS) have been used in the rehabilitation of cognitive function in a spectrum of neurological disorders. The present review outlines methodological communalities and differences of t-DCS procedures in neurocognitive rehabilitation. We consider the efficacy of tDCS for the management of specific cognitive deficits in four main neurological disorders by providing a critical analysis of recent studies that have used t-DCS to improve cognition in patients with Parkinson's Disease, Alzheimer's Disease, Hemi-spatial Neglect, and Aphasia. The evidence from this innovative approach to cognitive rehabilitation suggests that tDCS can influence cognition. However, the results show a high variability between studies both in terms of the methodological approach adopted and the cognitive functions targeted. The review also focuses both on methodological issues such as technical aspects of the stimulation (electrode position and dimension; current intensity; duration of protocol) and on the inclusion of appropriate assessment tools for cognition. A further aspect considered is the optimal timing for administration of tDCS: before, during or after cognitive rehabilitation. We conclude that more studies using common methodology are needed to gain a better understanding of the efficacy of tDCS as a new tool for rehabilitation of cognitive disorders in a range of neurological disorders.

No MeSH data available.


Related in: MedlinePlus

Scale representation of tDCS electrode montage of the reviewed studies with reference to the EEG international 10–20 system. In (A) legend of electrodes size and polarity and electrode montage in Parkinson's disease studies (Boggio et al., 2006; Pereira et al., 2013; Doruk et al., 2014), (B) Alzheimer's disease (Boggio et al., 2008, 2012; Ferrucci et al., 2008; Cotelli et al., 2014; Khedr et al., 2014; Penolazzi et al., 2014; Suemoto et al., 2014), (C) unilateral Neglect (Ko et al., 2008; Sparing et al., 2009; Sunwoo et al., 2013; Brem et al., 2014; Smit et al., 2015), and (D1,D2) Aphasia (Monti et al., 2008; Flöel et al., 2011; Fiori et al., 2011; Jung et al., 2011; Kang et al., 2011; You et al., 2011; Lee et al., 2013; Polanowska et al., 2013; Santos et al., 2013; Volpato et al., 2013; Marangolo et al., 2014; Manenti et al., 2015; Wu et al., 2015).
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Figure 2: Scale representation of tDCS electrode montage of the reviewed studies with reference to the EEG international 10–20 system. In (A) legend of electrodes size and polarity and electrode montage in Parkinson's disease studies (Boggio et al., 2006; Pereira et al., 2013; Doruk et al., 2014), (B) Alzheimer's disease (Boggio et al., 2008, 2012; Ferrucci et al., 2008; Cotelli et al., 2014; Khedr et al., 2014; Penolazzi et al., 2014; Suemoto et al., 2014), (C) unilateral Neglect (Ko et al., 2008; Sparing et al., 2009; Sunwoo et al., 2013; Brem et al., 2014; Smit et al., 2015), and (D1,D2) Aphasia (Monti et al., 2008; Flöel et al., 2011; Fiori et al., 2011; Jung et al., 2011; Kang et al., 2011; You et al., 2011; Lee et al., 2013; Polanowska et al., 2013; Santos et al., 2013; Volpato et al., 2013; Marangolo et al., 2014; Manenti et al., 2015; Wu et al., 2015).

Mentions: In this section we will review evidence on the use of tDCS for cognitive rehabilitation in patients with Parkinson's Disease, Alzheimer's Disease, Hemispatial Neglect or Aphasia. For each disorder we start with a concise description of the main features of cognitive deficit, followed by a detailed review of the studies. The methodological details of parameters of stimulation used in these studies are presented in Table 1. Patient characteristics, experimental design, cognitive domains targeted, tasks used as outcome measures and main results are summarized in Table 2. In Figures 2A–D is a visual representation of the electrode montage which could be useful to compare the studies.


Value and Efficacy of Transcranial Direct Current Stimulation in the Cognitive Rehabilitation: A Critical Review Since 2000.

Cappon D, Jahanshahi M, Bisiacchi P - Front Neurosci (2016)

Scale representation of tDCS electrode montage of the reviewed studies with reference to the EEG international 10–20 system. In (A) legend of electrodes size and polarity and electrode montage in Parkinson's disease studies (Boggio et al., 2006; Pereira et al., 2013; Doruk et al., 2014), (B) Alzheimer's disease (Boggio et al., 2008, 2012; Ferrucci et al., 2008; Cotelli et al., 2014; Khedr et al., 2014; Penolazzi et al., 2014; Suemoto et al., 2014), (C) unilateral Neglect (Ko et al., 2008; Sparing et al., 2009; Sunwoo et al., 2013; Brem et al., 2014; Smit et al., 2015), and (D1,D2) Aphasia (Monti et al., 2008; Flöel et al., 2011; Fiori et al., 2011; Jung et al., 2011; Kang et al., 2011; You et al., 2011; Lee et al., 2013; Polanowska et al., 2013; Santos et al., 2013; Volpato et al., 2013; Marangolo et al., 2014; Manenti et al., 2015; Wu et al., 2015).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4834357&req=5

Figure 2: Scale representation of tDCS electrode montage of the reviewed studies with reference to the EEG international 10–20 system. In (A) legend of electrodes size and polarity and electrode montage in Parkinson's disease studies (Boggio et al., 2006; Pereira et al., 2013; Doruk et al., 2014), (B) Alzheimer's disease (Boggio et al., 2008, 2012; Ferrucci et al., 2008; Cotelli et al., 2014; Khedr et al., 2014; Penolazzi et al., 2014; Suemoto et al., 2014), (C) unilateral Neglect (Ko et al., 2008; Sparing et al., 2009; Sunwoo et al., 2013; Brem et al., 2014; Smit et al., 2015), and (D1,D2) Aphasia (Monti et al., 2008; Flöel et al., 2011; Fiori et al., 2011; Jung et al., 2011; Kang et al., 2011; You et al., 2011; Lee et al., 2013; Polanowska et al., 2013; Santos et al., 2013; Volpato et al., 2013; Marangolo et al., 2014; Manenti et al., 2015; Wu et al., 2015).
Mentions: In this section we will review evidence on the use of tDCS for cognitive rehabilitation in patients with Parkinson's Disease, Alzheimer's Disease, Hemispatial Neglect or Aphasia. For each disorder we start with a concise description of the main features of cognitive deficit, followed by a detailed review of the studies. The methodological details of parameters of stimulation used in these studies are presented in Table 1. Patient characteristics, experimental design, cognitive domains targeted, tasks used as outcome measures and main results are summarized in Table 2. In Figures 2A–D is a visual representation of the electrode montage which could be useful to compare the studies.

Bottom Line: However, the results show a high variability between studies both in terms of the methodological approach adopted and the cognitive functions targeted.The review also focuses both on methodological issues such as technical aspects of the stimulation (electrode position and dimension; current intensity; duration of protocol) and on the inclusion of appropriate assessment tools for cognition.We conclude that more studies using common methodology are needed to gain a better understanding of the efficacy of tDCS as a new tool for rehabilitation of cognitive disorders in a range of neurological disorders.

View Article: PubMed Central - PubMed

Affiliation: Department of General Psychology, Center for Cognitive Neuroscience, University of Padova Padua, Italy.

ABSTRACT
Non-invasive brain stimulation techniques, including transcranial direct current stimulation (t-DCS) have been used in the rehabilitation of cognitive function in a spectrum of neurological disorders. The present review outlines methodological communalities and differences of t-DCS procedures in neurocognitive rehabilitation. We consider the efficacy of tDCS for the management of specific cognitive deficits in four main neurological disorders by providing a critical analysis of recent studies that have used t-DCS to improve cognition in patients with Parkinson's Disease, Alzheimer's Disease, Hemi-spatial Neglect, and Aphasia. The evidence from this innovative approach to cognitive rehabilitation suggests that tDCS can influence cognition. However, the results show a high variability between studies both in terms of the methodological approach adopted and the cognitive functions targeted. The review also focuses both on methodological issues such as technical aspects of the stimulation (electrode position and dimension; current intensity; duration of protocol) and on the inclusion of appropriate assessment tools for cognition. A further aspect considered is the optimal timing for administration of tDCS: before, during or after cognitive rehabilitation. We conclude that more studies using common methodology are needed to gain a better understanding of the efficacy of tDCS as a new tool for rehabilitation of cognitive disorders in a range of neurological disorders.

No MeSH data available.


Related in: MedlinePlus