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A case report of suspected hepatopulmonary syndrome secondary to ductal plate malformation with chronic active hepatitis in a dog.

Kaneko Y, Torisu S, Hagio M, Yamaguchi R, Mizutani S, Naganobu K - J. Vet. Med. Sci. (2015)

Bottom Line: A six-month-old Papillon was diagnosed with ductal plate malformation with chronic active hepatitis and showed progressive increases in AaDO2 over the course of the following six months.From these results, we suspected that this dog had HPS.This is the first description of suspected canine HPS.

View Article: PubMed Central - PubMed

Affiliation: Veterinary Teaching Hospital, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuen Kibanadai-nishi, Miyazaki 889-2192, Japan.

ABSTRACT
Hepatopulmonary syndrome (HPS) is a respiratory complication of hepatic disease, that is well recognized in humans and defined by the presence of 1) liver disease, 2) hypoxemia and/or high alveolar-arterial oxygen gradient (AaDO2) and 3) intrapulmonary vasodilatation. The present report describes a similar case of HPS in a dog. A six-month-old Papillon was diagnosed with ductal plate malformation with chronic active hepatitis and showed progressive increases in AaDO2 over the course of the following six months. The presence of intrapulmonary vasodilatation was confirmed by agitated saline contrast transthoracic echocardiography. Also, the absence of congenital cardiac defect was confirmed by transthoracic echocardiography. From these results, we suspected that this dog had HPS. This is the first description of suspected canine HPS.

No MeSH data available.


Related in: MedlinePlus

Ultrasonograph of the liver in the dog with ductal plate malformation. Ascites andmicrohepatia in the left lateral (LLL) and left medial lobes (LML) were noted. Theintrahepatic portal vein was not clearly identified.
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fig_001: Ultrasonograph of the liver in the dog with ductal plate malformation. Ascites andmicrohepatia in the left lateral (LLL) and left medial lobes (LML) were noted. Theintrahepatic portal vein was not clearly identified.

Mentions: RBC: red blood cell, PCV: packed cell volume, Hb: hemoglobin, MCV: mean corpuscularvolume, MCHC: mean corpuscular hemoglobin concentration, WBC: white blood cell, BUN:blood urea nitrogen, Cre: creatine, AST: aspartate aminotransferase, ALT: alanineaminotransferase, ALP: alkaline phosphatase, γ-GTP: gamma-glutamyl transpeptidase, TP:total protein, ALB: albumin, GLU: glucose, NH: ammonia, T-CHO: total cholesterol, TG:triglyceride, T-Bil: total bilirubin, CRP: C-reactive protein, SBA: serum bile acid, -,No data.


A case report of suspected hepatopulmonary syndrome secondary to ductal plate malformation with chronic active hepatitis in a dog.

Kaneko Y, Torisu S, Hagio M, Yamaguchi R, Mizutani S, Naganobu K - J. Vet. Med. Sci. (2015)

Ultrasonograph of the liver in the dog with ductal plate malformation. Ascites andmicrohepatia in the left lateral (LLL) and left medial lobes (LML) were noted. Theintrahepatic portal vein was not clearly identified.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4829524&req=5

fig_001: Ultrasonograph of the liver in the dog with ductal plate malformation. Ascites andmicrohepatia in the left lateral (LLL) and left medial lobes (LML) were noted. Theintrahepatic portal vein was not clearly identified.
Mentions: RBC: red blood cell, PCV: packed cell volume, Hb: hemoglobin, MCV: mean corpuscularvolume, MCHC: mean corpuscular hemoglobin concentration, WBC: white blood cell, BUN:blood urea nitrogen, Cre: creatine, AST: aspartate aminotransferase, ALT: alanineaminotransferase, ALP: alkaline phosphatase, γ-GTP: gamma-glutamyl transpeptidase, TP:total protein, ALB: albumin, GLU: glucose, NH: ammonia, T-CHO: total cholesterol, TG:triglyceride, T-Bil: total bilirubin, CRP: C-reactive protein, SBA: serum bile acid, -,No data.

Bottom Line: A six-month-old Papillon was diagnosed with ductal plate malformation with chronic active hepatitis and showed progressive increases in AaDO2 over the course of the following six months.From these results, we suspected that this dog had HPS.This is the first description of suspected canine HPS.

View Article: PubMed Central - PubMed

Affiliation: Veterinary Teaching Hospital, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuen Kibanadai-nishi, Miyazaki 889-2192, Japan.

ABSTRACT
Hepatopulmonary syndrome (HPS) is a respiratory complication of hepatic disease, that is well recognized in humans and defined by the presence of 1) liver disease, 2) hypoxemia and/or high alveolar-arterial oxygen gradient (AaDO2) and 3) intrapulmonary vasodilatation. The present report describes a similar case of HPS in a dog. A six-month-old Papillon was diagnosed with ductal plate malformation with chronic active hepatitis and showed progressive increases in AaDO2 over the course of the following six months. The presence of intrapulmonary vasodilatation was confirmed by agitated saline contrast transthoracic echocardiography. Also, the absence of congenital cardiac defect was confirmed by transthoracic echocardiography. From these results, we suspected that this dog had HPS. This is the first description of suspected canine HPS.

No MeSH data available.


Related in: MedlinePlus