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The co-existence of a myxoid liposarcoma and leiomyoma in the same ovarian mass of a dog.

Shiwa N, Boonsriroj H, Kimitsuki K, Shimatsu T, Park CH - J. Vet. Med. Sci. (2015)

Bottom Line: A 15-year-old, female mixed-breed dog presented with abdominal distention.The liposarcoma component was Alcian Blue- and Oil red O-positive, and demonstrated immunoreactivity with S-100, adipophilin and vimentin.Electron microscopy revealed that the tumor cell cytoplasms were packed with lipid vacuoles and dilated rough endoplasmic reticulum.

View Article: PubMed Central - PubMed

Affiliation: Department of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, 23-35-1 Higashi, Towada, Aomori 034-8628, Japan.

ABSTRACT
A 15-year-old, female mixed-breed dog presented with abdominal distention. An exploratory laparotomy revealed a large left ovarian mass (20 × 15 × 12 cm). Histopathological examination of the mass revealed a mixed myxoid liposarcoma and a well-differentiated leiomyoma. Four months after surgical removal of the mass, the dog died due to multiorgan metastasis. The metastasis was composed solely of the liposarcoma component. The liposarcoma component was Alcian Blue- and Oil red O-positive, and demonstrated immunoreactivity with S-100, adipophilin and vimentin. Electron microscopy revealed that the tumor cell cytoplasms were packed with lipid vacuoles and dilated rough endoplasmic reticulum. To our knowledge, this is the first report of myxoid liposarcoma and leiomyoma co-existing in a canine ovary.

No MeSH data available.


Related in: MedlinePlus

Myxoid liposarcoma area of the left ovary. The tumor cells are focally positive forS-100 protein. Immunohistochemistry. Bar=25 µm.
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fig_010: Myxoid liposarcoma area of the left ovary. The tumor cells are focally positive forS-100 protein. Immunohistochemistry. Bar=25 µm.

Mentions: Myxoid liposarcoma area of the left ovary. The tumor cells are diffusely positive foradipophilin. Immunohistochemistry. Bar=25 µm.


The co-existence of a myxoid liposarcoma and leiomyoma in the same ovarian mass of a dog.

Shiwa N, Boonsriroj H, Kimitsuki K, Shimatsu T, Park CH - J. Vet. Med. Sci. (2015)

Myxoid liposarcoma area of the left ovary. The tumor cells are focally positive forS-100 protein. Immunohistochemistry. Bar=25 µm.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4829519&req=5

fig_010: Myxoid liposarcoma area of the left ovary. The tumor cells are focally positive forS-100 protein. Immunohistochemistry. Bar=25 µm.
Mentions: Myxoid liposarcoma area of the left ovary. The tumor cells are diffusely positive foradipophilin. Immunohistochemistry. Bar=25 µm.

Bottom Line: A 15-year-old, female mixed-breed dog presented with abdominal distention.The liposarcoma component was Alcian Blue- and Oil red O-positive, and demonstrated immunoreactivity with S-100, adipophilin and vimentin.Electron microscopy revealed that the tumor cell cytoplasms were packed with lipid vacuoles and dilated rough endoplasmic reticulum.

View Article: PubMed Central - PubMed

Affiliation: Department of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, 23-35-1 Higashi, Towada, Aomori 034-8628, Japan.

ABSTRACT
A 15-year-old, female mixed-breed dog presented with abdominal distention. An exploratory laparotomy revealed a large left ovarian mass (20 × 15 × 12 cm). Histopathological examination of the mass revealed a mixed myxoid liposarcoma and a well-differentiated leiomyoma. Four months after surgical removal of the mass, the dog died due to multiorgan metastasis. The metastasis was composed solely of the liposarcoma component. The liposarcoma component was Alcian Blue- and Oil red O-positive, and demonstrated immunoreactivity with S-100, adipophilin and vimentin. Electron microscopy revealed that the tumor cell cytoplasms were packed with lipid vacuoles and dilated rough endoplasmic reticulum. To our knowledge, this is the first report of myxoid liposarcoma and leiomyoma co-existing in a canine ovary.

No MeSH data available.


Related in: MedlinePlus