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Colon Transit Time Test in Korean Children with Chronic Functional Constipation.

Yoo HY, Kim MR, Park HW, Son JS, Bae SH - Pediatr Gastroenterol Hepatol Nutr (2016)

Bottom Line: The aim of this study is to describe the results of colon transit time (CTT) tests in Korean children who had chronic functional constipation based on highly refined data.Two hundreds twenty-five children were excluded on the basis of CTT test result, defecation diary, and clinical setting.The frequency of subtype between non-encopresis group and encopresis was statistically significant (p=0.002).

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Konkuk University School of Medicine, Seoul, Korea.

ABSTRACT

Purpose: Each ethnic group has a unique life style, including diets. Life style affects bowel movement. The aim of this study is to describe the results of colon transit time (CTT) tests in Korean children who had chronic functional constipation based on highly refined data.

Methods: One hundred ninety (86 males) out of 415 children who performed a CTT test under the diagnosis of chronic constipation according to Rome III criteria at Konkuk University Medical Center from January 2006 through March 2015 were enrolled in this study. Two hundreds twenty-five children were excluded on the basis of CTT test result, defecation diary, and clinical setting. Shapiro-Wilk and Mann-Whitney U, and chi-square tests were used for statistical analysis.

Results: The median value and interquartile range (IQR) of CTT was 54 (37.5) hours in Encopresis group, and those in non-encopresis group was 40.2 (27.9) hours (p<0.001). The frequency of subtype between non-encopresis group and encopresis was statistically significant (p=0.002). The non-encopresis group (n=154, 81.1%) was divided into normal transit subgroup (n=84, 54.5%; median value and IQR of CTT=26.4 [9.6] hours), outlet obstruction subgroup (n=18, 11.7%; 62.4 [15.6] hours), and slow transit subgroup (n=52, 33.8%; 54.6 [21.0] hours]. The encopresis group (n=36, 18.9%) was divided into normal transit subgroup (n=8, 22.2%; median value and IQR of CTT=32.4 [9.9] hours), outlet obstruction subgroup (n=8, 22.2%; 67.8 [34.8] hours), and slow transit subgroup (n=20, 55.6%; 59.4 [62.7]hours).

Conclusion: This study provided the basic pattern and value of the CTT test in Korean children with chronic constipation.

No MeSH data available.


Related in: MedlinePlus

Algorithm to select enrolled patients. Four hundreds fourteen children with constipation were screened on the basis of defecation diary, colon transit time test, and clinical status. Some of the patients were overlaped during screening. Finally, 190 children were enrolled in this study. *Acute illness state or patient had better defecation during the colon transit time test than on medication. †Puborectalis failure (n=4), imperforate anus (n=1), intracranial hemorrhage (n=1), anticonvulsant medication (n=2), extreme obesity (n=1).
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Figure 1: Algorithm to select enrolled patients. Four hundreds fourteen children with constipation were screened on the basis of defecation diary, colon transit time test, and clinical status. Some of the patients were overlaped during screening. Finally, 190 children were enrolled in this study. *Acute illness state or patient had better defecation during the colon transit time test than on medication. †Puborectalis failure (n=4), imperforate anus (n=1), intracranial hemorrhage (n=1), anticonvulsant medication (n=2), extreme obesity (n=1).

Mentions: Two hundreds twenty-four children were excluded from 414 children on the basis of exclusion criteria. Finally 190 children were enrolled in this study. Some of the children overlapped during screening. Exclusion criteria were as follows: (1) the sum of retained radio-opaque markers on the 4th and 7th day was same or less than 10 on the CTT test (n=85); (2) during the CTT test, there was acute illness or the pattern of defecation was better than that of the 'on medicine period' on the basis of the defecation diary (n=155); (3) underlying diseases (n=9); failure of the puborectalis muscle relax (n=4), imperforated anus (n=1), intracranial hemorrhage (n=1), extreme obesity (n=1), and epilepsy (n=2); (4) older than 16 years (n=8) (Fig. 1).


Colon Transit Time Test in Korean Children with Chronic Functional Constipation.

Yoo HY, Kim MR, Park HW, Son JS, Bae SH - Pediatr Gastroenterol Hepatol Nutr (2016)

Algorithm to select enrolled patients. Four hundreds fourteen children with constipation were screened on the basis of defecation diary, colon transit time test, and clinical status. Some of the patients were overlaped during screening. Finally, 190 children were enrolled in this study. *Acute illness state or patient had better defecation during the colon transit time test than on medication. †Puborectalis failure (n=4), imperforate anus (n=1), intracranial hemorrhage (n=1), anticonvulsant medication (n=2), extreme obesity (n=1).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4821981&req=5

Figure 1: Algorithm to select enrolled patients. Four hundreds fourteen children with constipation were screened on the basis of defecation diary, colon transit time test, and clinical status. Some of the patients were overlaped during screening. Finally, 190 children were enrolled in this study. *Acute illness state or patient had better defecation during the colon transit time test than on medication. †Puborectalis failure (n=4), imperforate anus (n=1), intracranial hemorrhage (n=1), anticonvulsant medication (n=2), extreme obesity (n=1).
Mentions: Two hundreds twenty-four children were excluded from 414 children on the basis of exclusion criteria. Finally 190 children were enrolled in this study. Some of the children overlapped during screening. Exclusion criteria were as follows: (1) the sum of retained radio-opaque markers on the 4th and 7th day was same or less than 10 on the CTT test (n=85); (2) during the CTT test, there was acute illness or the pattern of defecation was better than that of the 'on medicine period' on the basis of the defecation diary (n=155); (3) underlying diseases (n=9); failure of the puborectalis muscle relax (n=4), imperforated anus (n=1), intracranial hemorrhage (n=1), extreme obesity (n=1), and epilepsy (n=2); (4) older than 16 years (n=8) (Fig. 1).

Bottom Line: The aim of this study is to describe the results of colon transit time (CTT) tests in Korean children who had chronic functional constipation based on highly refined data.Two hundreds twenty-five children were excluded on the basis of CTT test result, defecation diary, and clinical setting.The frequency of subtype between non-encopresis group and encopresis was statistically significant (p=0.002).

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Konkuk University School of Medicine, Seoul, Korea.

ABSTRACT

Purpose: Each ethnic group has a unique life style, including diets. Life style affects bowel movement. The aim of this study is to describe the results of colon transit time (CTT) tests in Korean children who had chronic functional constipation based on highly refined data.

Methods: One hundred ninety (86 males) out of 415 children who performed a CTT test under the diagnosis of chronic constipation according to Rome III criteria at Konkuk University Medical Center from January 2006 through March 2015 were enrolled in this study. Two hundreds twenty-five children were excluded on the basis of CTT test result, defecation diary, and clinical setting. Shapiro-Wilk and Mann-Whitney U, and chi-square tests were used for statistical analysis.

Results: The median value and interquartile range (IQR) of CTT was 54 (37.5) hours in Encopresis group, and those in non-encopresis group was 40.2 (27.9) hours (p<0.001). The frequency of subtype between non-encopresis group and encopresis was statistically significant (p=0.002). The non-encopresis group (n=154, 81.1%) was divided into normal transit subgroup (n=84, 54.5%; median value and IQR of CTT=26.4 [9.6] hours), outlet obstruction subgroup (n=18, 11.7%; 62.4 [15.6] hours), and slow transit subgroup (n=52, 33.8%; 54.6 [21.0] hours]. The encopresis group (n=36, 18.9%) was divided into normal transit subgroup (n=8, 22.2%; median value and IQR of CTT=32.4 [9.9] hours), outlet obstruction subgroup (n=8, 22.2%; 67.8 [34.8] hours), and slow transit subgroup (n=20, 55.6%; 59.4 [62.7]hours).

Conclusion: This study provided the basic pattern and value of the CTT test in Korean children with chronic constipation.

No MeSH data available.


Related in: MedlinePlus