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Metastases of malignant melanoma to stomach.

Kuzu UB, Suna N, Gokcan H, Abdullazade S, Öztas E, Odemis B - Prz Gastroenterol (2016)

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey.

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Malignant melanoma (MM) is one of the most common tumours that metastasises to the gastrointestinal (GI) tract... He had a history of localised cutaneous MM excision from the right thigh 5 years earlier... Lab work showed no significant abnormality on blood biochemistry... Malignant melanoma may involve the GI tract as a metastatic lesion, or rarely as a primary tumour... However, a histopathological exam may not differentiate a primary lesion from a metastatic one... Immunohistochemistry should be employed to prove MM with markers such as HMB-45 and S100... Treatment options for metastatic involvement of the GI tract with MM are surgery, chemotherapy, immunotherapy, and palliative therapy... Only surgery is reported to increase survival to some extent... As a result, because MM metastasis may show up years later, we suggest screening of GI tract in MM patients if there is the presence of GI symptoms.

No MeSH data available.


Related in: MedlinePlus

A–C. Malignant melanoma metastasis in stomach; diffusely spread black-pigmented lesions at gastric mucosa in esophagogastroduodenoscopy
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Figure 0001: A–C. Malignant melanoma metastasis in stomach; diffusely spread black-pigmented lesions at gastric mucosa in esophagogastroduodenoscopy

Mentions: A 58-year-old male patient applied to the gastroenterology outpatient clinic with nausea and epigastric pain. He had a history of localised cutaneous MM excision from the right thigh 5 years earlier. Lab work showed no significant abnormality on blood biochemistry. His esophagogastroduodenoscopy showed multiple, black-pigmented lesions of various sizes (Figure 1). A biopsy from these lesions revealed MM metastasis (Figure 2).


Metastases of malignant melanoma to stomach.

Kuzu UB, Suna N, Gokcan H, Abdullazade S, Öztas E, Odemis B - Prz Gastroenterol (2016)

A–C. Malignant melanoma metastasis in stomach; diffusely spread black-pigmented lesions at gastric mucosa in esophagogastroduodenoscopy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4814540&req=5

Figure 0001: A–C. Malignant melanoma metastasis in stomach; diffusely spread black-pigmented lesions at gastric mucosa in esophagogastroduodenoscopy
Mentions: A 58-year-old male patient applied to the gastroenterology outpatient clinic with nausea and epigastric pain. He had a history of localised cutaneous MM excision from the right thigh 5 years earlier. Lab work showed no significant abnormality on blood biochemistry. His esophagogastroduodenoscopy showed multiple, black-pigmented lesions of various sizes (Figure 1). A biopsy from these lesions revealed MM metastasis (Figure 2).

View Article: PubMed Central - PubMed

Affiliation: Department of Gastroenterology, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Malignant melanoma (MM) is one of the most common tumours that metastasises to the gastrointestinal (GI) tract... He had a history of localised cutaneous MM excision from the right thigh 5 years earlier... Lab work showed no significant abnormality on blood biochemistry... Malignant melanoma may involve the GI tract as a metastatic lesion, or rarely as a primary tumour... However, a histopathological exam may not differentiate a primary lesion from a metastatic one... Immunohistochemistry should be employed to prove MM with markers such as HMB-45 and S100... Treatment options for metastatic involvement of the GI tract with MM are surgery, chemotherapy, immunotherapy, and palliative therapy... Only surgery is reported to increase survival to some extent... As a result, because MM metastasis may show up years later, we suggest screening of GI tract in MM patients if there is the presence of GI symptoms.

No MeSH data available.


Related in: MedlinePlus