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Strongyloides stercoralis hyperinfection in patient with autoimmune hepatitis and purpura fulminans.

Rathor N, Khillan V, Sarin SK - Indian J Crit Care Med (2016)

Bottom Line: It is known to occur with a change in immune status of the host; this can occur due to immunosuppressants.Cytomegalovirus (CMV) is also known to suppress host immunity.Due to the nonspecific presentation, the diagnosis is frequently missed, and the outcome remains poor with 15-87% mortality despite therapy.

View Article: PubMed Central - PubMed

Affiliation: Department of Microbiology, Institute of Liver and Biliary Sciences, New Delhi, India.

ABSTRACT
Strongyloidiosis is usually an asymptomatic chronic nematodal disease. The term hyperinfection is used to denote autoinfection, a phenomenon in which the number of worms increases enormously. Development or exacerbation of gastrointestinal and pulmonary symptoms is seen, (A) and the detection of increased numbers of larvae in stool and or sputum is the hallmark. It is known to occur with a change in immune status of the host; this can occur due to immunosuppressants. Cytomegalovirus (CMV) is also known to suppress host immunity. Due to the nonspecific presentation, the diagnosis is frequently missed, and the outcome remains poor with 15-87% mortality despite therapy. We report here a case of Strongyloides stercoralis hyperinfection following immunosuppressive therapy for autoimmune hepatitis and concomitant CMV infection with purpura fulminance and frank sepsis, with fatal outcome.

No MeSH data available.


Related in: MedlinePlus

Double bulb esophagus
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Figure 2: Double bulb esophagus


Strongyloides stercoralis hyperinfection in patient with autoimmune hepatitis and purpura fulminans.

Rathor N, Khillan V, Sarin SK - Indian J Crit Care Med (2016)

Double bulb esophagus
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4759996&req=5

Figure 2: Double bulb esophagus
Bottom Line: It is known to occur with a change in immune status of the host; this can occur due to immunosuppressants.Cytomegalovirus (CMV) is also known to suppress host immunity.Due to the nonspecific presentation, the diagnosis is frequently missed, and the outcome remains poor with 15-87% mortality despite therapy.

View Article: PubMed Central - PubMed

Affiliation: Department of Microbiology, Institute of Liver and Biliary Sciences, New Delhi, India.

ABSTRACT
Strongyloidiosis is usually an asymptomatic chronic nematodal disease. The term hyperinfection is used to denote autoinfection, a phenomenon in which the number of worms increases enormously. Development or exacerbation of gastrointestinal and pulmonary symptoms is seen, (A) and the detection of increased numbers of larvae in stool and or sputum is the hallmark. It is known to occur with a change in immune status of the host; this can occur due to immunosuppressants. Cytomegalovirus (CMV) is also known to suppress host immunity. Due to the nonspecific presentation, the diagnosis is frequently missed, and the outcome remains poor with 15-87% mortality despite therapy. We report here a case of Strongyloides stercoralis hyperinfection following immunosuppressive therapy for autoimmune hepatitis and concomitant CMV infection with purpura fulminance and frank sepsis, with fatal outcome.

No MeSH data available.


Related in: MedlinePlus