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Primary mediastinal dedifferentiated liposarcoma resected by lateral thoracotomy with video-assisted thoracoscopic surgery.

Hamanaka K, Ohashi M, Nakamura T - J Surg Case Rep (2016)

Bottom Line: A 74-year-old man was admitted to our hospital with a left intrathoracic tumor ∼10 cm in diameter.The tumor was resected by left lateral thoracotomy with video-assisted thoracoscopic surgery.No evidence of recurrence has been seen as of 8 months postoperatively.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Thoracic Surgery, Suwa Red Cross Hospital, Suwa, Nagano, Japan Department of Thoracic Surgery, Shinshu University School of Medicine, Matsumoto, Nagano, Japan kham@shinshu-u.ac.jp.

No MeSH data available.


Related in: MedlinePlus

Gross appearance of the tumor. The well-circumscribed mass is encapsulated by fibrous tissue, showing a myxoid appearance intermingled with a whitish, solid part on the cut surface.
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RJV163F4: Gross appearance of the tumor. The well-circumscribed mass is encapsulated by fibrous tissue, showing a myxoid appearance intermingled with a whitish, solid part on the cut surface.

Mentions: Extirpation of the tumor was performed with a 15-cm left lateral incision assisted with a thoracoscope. The tumor appeared smooth and encapsulated, and appeared to have originated from mediastinal fat tissue. No adhesion between the tumor and descending aorta was evident, although fibrous adhesion between the tumor and lung was present without direct invasion. Grossly, the extirpated tumor was well circumscribed, ∼11 × 8 × 7 cm in size and encapsulated by thin, fibrous tissue. The cut surface revealed a myxoid appearance, partially intermingled with a whitish, solid part (Fig. 4). Histopathologically, the myxoid area showed proliferation of pleomorphic tumor cells such as plump spindle-shaped cells, stellate cells and large atypical cells with bizarre nuclei, embedded in myxoid stroma. The whitish, fibrous part comprised dense fibrous stroma containing scattered pleomorphic tumor cells and partially intermingled with mature fat tissue, showing features of well-differentiated liposarcoma (Fig. 5A and B). Immunohistochemistry revealed positive nuclear staining for CDK4 and MDM2 in both myxoid and fibrous parts of the tumor (Fig. 5C and D). Dedifferentiated liposarcoma was therefore diagnosed.Figure 4:


Primary mediastinal dedifferentiated liposarcoma resected by lateral thoracotomy with video-assisted thoracoscopic surgery.

Hamanaka K, Ohashi M, Nakamura T - J Surg Case Rep (2016)

Gross appearance of the tumor. The well-circumscribed mass is encapsulated by fibrous tissue, showing a myxoid appearance intermingled with a whitish, solid part on the cut surface.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4697920&req=5

RJV163F4: Gross appearance of the tumor. The well-circumscribed mass is encapsulated by fibrous tissue, showing a myxoid appearance intermingled with a whitish, solid part on the cut surface.
Mentions: Extirpation of the tumor was performed with a 15-cm left lateral incision assisted with a thoracoscope. The tumor appeared smooth and encapsulated, and appeared to have originated from mediastinal fat tissue. No adhesion between the tumor and descending aorta was evident, although fibrous adhesion between the tumor and lung was present without direct invasion. Grossly, the extirpated tumor was well circumscribed, ∼11 × 8 × 7 cm in size and encapsulated by thin, fibrous tissue. The cut surface revealed a myxoid appearance, partially intermingled with a whitish, solid part (Fig. 4). Histopathologically, the myxoid area showed proliferation of pleomorphic tumor cells such as plump spindle-shaped cells, stellate cells and large atypical cells with bizarre nuclei, embedded in myxoid stroma. The whitish, fibrous part comprised dense fibrous stroma containing scattered pleomorphic tumor cells and partially intermingled with mature fat tissue, showing features of well-differentiated liposarcoma (Fig. 5A and B). Immunohistochemistry revealed positive nuclear staining for CDK4 and MDM2 in both myxoid and fibrous parts of the tumor (Fig. 5C and D). Dedifferentiated liposarcoma was therefore diagnosed.Figure 4:

Bottom Line: A 74-year-old man was admitted to our hospital with a left intrathoracic tumor ∼10 cm in diameter.The tumor was resected by left lateral thoracotomy with video-assisted thoracoscopic surgery.No evidence of recurrence has been seen as of 8 months postoperatively.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Thoracic Surgery, Suwa Red Cross Hospital, Suwa, Nagano, Japan Department of Thoracic Surgery, Shinshu University School of Medicine, Matsumoto, Nagano, Japan kham@shinshu-u.ac.jp.

No MeSH data available.


Related in: MedlinePlus