Limits...
Long and short range order structural analysis of In-situ formed biphasic calcium phosphates.

Kim DH, Hwang KH, Lee JD, Park HC, Yoon SY - Biomater Res (2015)

Bottom Line: In this study, BCP were prepared by aqueous co-precipitation and calcination method.The refined structural parameters of in-situ formed BCP confirmed that all the investigated structures have crystallized in the corresponding hexagonal (space group P63/m) and rhombohedral (space group R3c) structures.The significant short range order structural change of BCP was determined by Raman analysis.

View Article: PubMed Central - PubMed

Affiliation: School of Materials Science and Engineering, Pusan National University, Busan, 609-735 Republic of Korea.

ABSTRACT

Background: Biphasic calcium phosphates (BCP) have attracted considerable attention as a bone graft substitute. In this study, BCP were prepared by aqueous co-precipitation and calcination method. The crystal phases of in-situ formed BCP consisting of hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) were controlled by the degree of calcium deficiency of precursors. The long and short range order structures of biphasic mixtures was investigated using Rietveld refinement technique and high resolution Raman spectroscopy. The refined structural parameters of in-situ formed BCP confirmed that all the investigated structures have crystallized in the corresponding hexagonal (space group P63/m) and rhombohedral (space group R3c) structures.

Results: The crystal phases, Ca/P molar ratio, and lattice parameters of in-situ formed BCP consisting of HAp and β-TCP were controlled by the degree of calcium deficiency of calcium phosphate precursors. The significant short range order structural change of BCP was determined by Raman analysis.

Conclusions: The long and short range order structural changes of in-situ formed BCP might be due to the coexistence of β-TCP and HAp crystal phases.

No MeSH data available.


Related in: MedlinePlus

a Symmetric vibration (stretching mode, ν1) of PO34− of β-TCP, HAp, mechanical mixed BCP, and in-situ formed BCP and b pseudo Gaussian fitting results from Raman spectra of in-situ formed BCP
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
getmorefigures.php?uid=PMC4697325&req=5

Fig3: a Symmetric vibration (stretching mode, ν1) of PO34− of β-TCP, HAp, mechanical mixed BCP, and in-situ formed BCP and b pseudo Gaussian fitting results from Raman spectra of in-situ formed BCP

Mentions: Figure 3 shows the short range order structural analysis of in-situ formed BCP. Figure 3(a) shows the Raman spectra of β-TCP, HAp, mechanical mixed BCP, and in-situ formed BCP, assigned to a symmetric P-O vibration (stretching mode, ν1) within the PO34− group. Among the spectra shown in Fig. 3(a), it is spectrum of the in-situ formed BCP that is most similar to spectra observed from mixture of pure β-TCP and HAp. However, it is evident that P-O vibration peak (i.e., 968 cm−1 of β-TCP) of in-situ formed BCP (i.e., 43.8 % of β-TCP and 56.2 % of HAp determined by Rietveld analysis) indicated a peak shift, compared with monophasic β-TCP and mechanical mixed BCP (i.e., 44 % of β-TCP and 56 % of HAp), as shown in Fig. 3(b). Therefore, the short range order structure of in-situ formed BCP could be considered to be affected by the coexistence of β-TCP and HAp phase.Fig. 3


Long and short range order structural analysis of In-situ formed biphasic calcium phosphates.

Kim DH, Hwang KH, Lee JD, Park HC, Yoon SY - Biomater Res (2015)

a Symmetric vibration (stretching mode, ν1) of PO34− of β-TCP, HAp, mechanical mixed BCP, and in-situ formed BCP and b pseudo Gaussian fitting results from Raman spectra of in-situ formed BCP
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4697325&req=5

Fig3: a Symmetric vibration (stretching mode, ν1) of PO34− of β-TCP, HAp, mechanical mixed BCP, and in-situ formed BCP and b pseudo Gaussian fitting results from Raman spectra of in-situ formed BCP
Mentions: Figure 3 shows the short range order structural analysis of in-situ formed BCP. Figure 3(a) shows the Raman spectra of β-TCP, HAp, mechanical mixed BCP, and in-situ formed BCP, assigned to a symmetric P-O vibration (stretching mode, ν1) within the PO34− group. Among the spectra shown in Fig. 3(a), it is spectrum of the in-situ formed BCP that is most similar to spectra observed from mixture of pure β-TCP and HAp. However, it is evident that P-O vibration peak (i.e., 968 cm−1 of β-TCP) of in-situ formed BCP (i.e., 43.8 % of β-TCP and 56.2 % of HAp determined by Rietveld analysis) indicated a peak shift, compared with monophasic β-TCP and mechanical mixed BCP (i.e., 44 % of β-TCP and 56 % of HAp), as shown in Fig. 3(b). Therefore, the short range order structure of in-situ formed BCP could be considered to be affected by the coexistence of β-TCP and HAp phase.Fig. 3

Bottom Line: In this study, BCP were prepared by aqueous co-precipitation and calcination method.The refined structural parameters of in-situ formed BCP confirmed that all the investigated structures have crystallized in the corresponding hexagonal (space group P63/m) and rhombohedral (space group R3c) structures.The significant short range order structural change of BCP was determined by Raman analysis.

View Article: PubMed Central - PubMed

Affiliation: School of Materials Science and Engineering, Pusan National University, Busan, 609-735 Republic of Korea.

ABSTRACT

Background: Biphasic calcium phosphates (BCP) have attracted considerable attention as a bone graft substitute. In this study, BCP were prepared by aqueous co-precipitation and calcination method. The crystal phases of in-situ formed BCP consisting of hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) were controlled by the degree of calcium deficiency of precursors. The long and short range order structures of biphasic mixtures was investigated using Rietveld refinement technique and high resolution Raman spectroscopy. The refined structural parameters of in-situ formed BCP confirmed that all the investigated structures have crystallized in the corresponding hexagonal (space group P63/m) and rhombohedral (space group R3c) structures.

Results: The crystal phases, Ca/P molar ratio, and lattice parameters of in-situ formed BCP consisting of HAp and β-TCP were controlled by the degree of calcium deficiency of calcium phosphate precursors. The significant short range order structural change of BCP was determined by Raman analysis.

Conclusions: The long and short range order structural changes of in-situ formed BCP might be due to the coexistence of β-TCP and HAp crystal phases.

No MeSH data available.


Related in: MedlinePlus