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Characterizing HIV epidemiology in stable couples in Cambodia, the Dominican Republic, Haiti, and India.

Chemaitelly H, Abu-Raddad LJ - Epidemiol. Infect. (2015)

Bottom Line: The majority of HIV incidence in the population occurred through extra-partner encounters in SCs.There is similarity in HIV epidemiology in SCs between these countries and countries in sub-Saharan Africa, despite the difference in scale of epidemics.It appears that HIV epidemiology in SCs may share similar patterns globally, possibly because it is a natural 'spillover' effect of HIV dynamics in high-risk populations.

View Article: PubMed Central - PubMed

Affiliation: Infectious Disease Epidemiology Group,Weill Cornell Medical College - Qatar,Cornell University,Qatar Foundation - Education City,Doha,Qatar.

ABSTRACT
Using a set of statistical methods and HIV mathematical models applied on nationally representative Demographic and Health Survey data, we characterized HIV serodiscordancy patterns and HIV transmission dynamics in stable couples (SCs) in four countries: Cambodia, the Dominican Republic, Haiti, and India. The majority of SCs affected by HIV were serodiscordant, and about a third of HIV-infected persons had uninfected partners. Overall, nearly two-thirds of HIV infections occurred in individuals in SCs, but only about half of these infections were due to transmissions within serodiscordant couples. The majority of HIV incidence in the population occurred through extra-partner encounters in SCs. There is similarity in HIV epidemiology in SCs between these countries and countries in sub-Saharan Africa, despite the difference in scale of epidemics. It appears that HIV epidemiology in SCs may share similar patterns globally, possibly because it is a natural 'spillover' effect of HIV dynamics in high-risk populations.

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Patterns of HIV serodiscordancy in India, Cambodia, the Dominican Republic, and Haiticompared to those in low and high HIV prevalence countries in sub-Saharan Africa.Countries are shown in order of increasing HIV prevalence.
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fig01: Patterns of HIV serodiscordancy in India, Cambodia, the Dominican Republic, and Haiticompared to those in low and high HIV prevalence countries in sub-Saharan Africa.Countries are shown in order of increasing HIV prevalence.

Mentions: The socio-demographic and health characteristics of the male, female and SC populationsacross countries can be found in Supplementary Tables S1 and S2. Overall, the countries arecharacterized by low HIV prevalence, measured at <1% in India, Cambodia, and theDominican Republic, at 2·2% in Haiti and at 3·3% in Bateyes-Dominican Republic. The majorityof the population of reproductive age in these countries is engaged in SCs (Fig. 1a). A substantial fraction ofHIV-infected individuals are also in SCs: 69% in India, 76% in Cambodia, 56% in the DominicanRepublic, 60% in Haiti, and 65% in Bateyes-Dominican Republic (Fig. 1b). If we were to randomly draw couples from thepopulation, less than one couple in every 100 couples would be HIV serodiscordant in each ofIndia, Cambodia, and the Dominican Republic, compared to three couples in Haiti and fourcouples in Bateyes-Dominican Republic (Fig.1c). Moreover, less than one couple in every 100 couples would beaffected by HIV (serodiscordant or concordant positive) in India, compared to one couple inCambodia and the Dominican Republic, four couples in Haiti and six couples inBateyes-Dominican Republic. Fig. 1.


Characterizing HIV epidemiology in stable couples in Cambodia, the Dominican Republic, Haiti, and India.

Chemaitelly H, Abu-Raddad LJ - Epidemiol. Infect. (2015)

Patterns of HIV serodiscordancy in India, Cambodia, the Dominican Republic, and Haiticompared to those in low and high HIV prevalence countries in sub-Saharan Africa.Countries are shown in order of increasing HIV prevalence.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4697301&req=5

fig01: Patterns of HIV serodiscordancy in India, Cambodia, the Dominican Republic, and Haiticompared to those in low and high HIV prevalence countries in sub-Saharan Africa.Countries are shown in order of increasing HIV prevalence.
Mentions: The socio-demographic and health characteristics of the male, female and SC populationsacross countries can be found in Supplementary Tables S1 and S2. Overall, the countries arecharacterized by low HIV prevalence, measured at <1% in India, Cambodia, and theDominican Republic, at 2·2% in Haiti and at 3·3% in Bateyes-Dominican Republic. The majorityof the population of reproductive age in these countries is engaged in SCs (Fig. 1a). A substantial fraction ofHIV-infected individuals are also in SCs: 69% in India, 76% in Cambodia, 56% in the DominicanRepublic, 60% in Haiti, and 65% in Bateyes-Dominican Republic (Fig. 1b). If we were to randomly draw couples from thepopulation, less than one couple in every 100 couples would be HIV serodiscordant in each ofIndia, Cambodia, and the Dominican Republic, compared to three couples in Haiti and fourcouples in Bateyes-Dominican Republic (Fig.1c). Moreover, less than one couple in every 100 couples would beaffected by HIV (serodiscordant or concordant positive) in India, compared to one couple inCambodia and the Dominican Republic, four couples in Haiti and six couples inBateyes-Dominican Republic. Fig. 1.

Bottom Line: The majority of HIV incidence in the population occurred through extra-partner encounters in SCs.There is similarity in HIV epidemiology in SCs between these countries and countries in sub-Saharan Africa, despite the difference in scale of epidemics.It appears that HIV epidemiology in SCs may share similar patterns globally, possibly because it is a natural 'spillover' effect of HIV dynamics in high-risk populations.

View Article: PubMed Central - PubMed

Affiliation: Infectious Disease Epidemiology Group,Weill Cornell Medical College - Qatar,Cornell University,Qatar Foundation - Education City,Doha,Qatar.

ABSTRACT
Using a set of statistical methods and HIV mathematical models applied on nationally representative Demographic and Health Survey data, we characterized HIV serodiscordancy patterns and HIV transmission dynamics in stable couples (SCs) in four countries: Cambodia, the Dominican Republic, Haiti, and India. The majority of SCs affected by HIV were serodiscordant, and about a third of HIV-infected persons had uninfected partners. Overall, nearly two-thirds of HIV infections occurred in individuals in SCs, but only about half of these infections were due to transmissions within serodiscordant couples. The majority of HIV incidence in the population occurred through extra-partner encounters in SCs. There is similarity in HIV epidemiology in SCs between these countries and countries in sub-Saharan Africa, despite the difference in scale of epidemics. It appears that HIV epidemiology in SCs may share similar patterns globally, possibly because it is a natural 'spillover' effect of HIV dynamics in high-risk populations.

Show MeSH
Related in: MedlinePlus