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Anaesthesia practice and reproductive outcomes: Facts unveiled.

Nagella AB, Ravishankar M, Hemanth Kumar VR - Indian J Anaesth (2015)

Bottom Line: Female anaesthesiologists when compared with spouses of male anaesthesiologists faced more difficulty with conception (P = 0.015).Female anaesthesiologists who worked in the operating room (OR) in their first trimester of gestation had a higher incidence of spontaneous abortions than those who did not work in the OR (P = 0.05).Both female anaesthesiologists and spouses of male anaesthesiologists had a greater risk for a first trimester miscarriage than the general population.

View Article: PubMed Central - PubMed

Affiliation: Department of Anesthesiology and Critical Care, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Puducherry, India.

ABSTRACT

Background and aims: Anaesthetic practice is associated with a risk of chronic exposure to anaesthetic agents. With the advent of newer inhalational agents and changing anaesthetic practices, the risks for anaesthesiologists with regard to adverse reproductive outcomes is unknown. Hence, a nationwide online survey was conducted to study the anaesthetic practices prevalent in India and their association, if any, with poor reproductive outcomes.

Methods: The online survey involved 9974 anaesthesiologists. A questionnaire soliciting information regarding anaesthetic practice techniques, reproductive outcomes and perinatal outcomes was designed. All the anaesthesiologists in the ISA National database were mailed a link to the above questionnaire.

Results: Female anaesthesiologists and spouses of male anaesthesiologists had a higher incidence of first trimester spontaneous abortions than the general population. Female anaesthesiologists when compared with spouses of male anaesthesiologists faced more difficulty with conception (P = 0.015). Female anaesthesiologists who worked in the operating room (OR) in their first trimester of gestation had a higher incidence of spontaneous abortions than those who did not work in the OR (P = 0.05). Longer hours of general anaesthesia conducted in the first trimester of pregnancy was associated with a higher risk of birth defects in their progeny (P = 0.05).

Conclusion: Spontaneous abortions and birth defects were higher in female anaesthesiologists who worked in the OR in the first trimester of gestation. Both female anaesthesiologists and spouses of male anaesthesiologists had a greater risk for a first trimester miscarriage than the general population.

No MeSH data available.


Related in: MedlinePlus

Age distribution and duration of anaesthetic practice pattern of the survey respondents
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Figure 2: Age distribution and duration of anaesthetic practice pattern of the survey respondents

Mentions: Distribution of respondents with respect to their age and number of years of anaesthetic practice as in Figure 2 suggests a representative sample of the entire anaesthesiologist population in India. Of all the respondents, 90% still use N2O in their practice. The pattern of usage of inhalational agents [Figure 3] shows isoflurane and sevoflurane to be the commonly used agents in our country. A total of 6.8% respondents used a fresh gas flow <1 L/min routinely and only 15% used a scavenging system for waste anaesthetic gases in their ORs [Figure 4].


Anaesthesia practice and reproductive outcomes: Facts unveiled.

Nagella AB, Ravishankar M, Hemanth Kumar VR - Indian J Anaesth (2015)

Age distribution and duration of anaesthetic practice pattern of the survey respondents
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4697242&req=5

Figure 2: Age distribution and duration of anaesthetic practice pattern of the survey respondents
Mentions: Distribution of respondents with respect to their age and number of years of anaesthetic practice as in Figure 2 suggests a representative sample of the entire anaesthesiologist population in India. Of all the respondents, 90% still use N2O in their practice. The pattern of usage of inhalational agents [Figure 3] shows isoflurane and sevoflurane to be the commonly used agents in our country. A total of 6.8% respondents used a fresh gas flow <1 L/min routinely and only 15% used a scavenging system for waste anaesthetic gases in their ORs [Figure 4].

Bottom Line: Female anaesthesiologists when compared with spouses of male anaesthesiologists faced more difficulty with conception (P = 0.015).Female anaesthesiologists who worked in the operating room (OR) in their first trimester of gestation had a higher incidence of spontaneous abortions than those who did not work in the OR (P = 0.05).Both female anaesthesiologists and spouses of male anaesthesiologists had a greater risk for a first trimester miscarriage than the general population.

View Article: PubMed Central - PubMed

Affiliation: Department of Anesthesiology and Critical Care, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Puducherry, India.

ABSTRACT

Background and aims: Anaesthetic practice is associated with a risk of chronic exposure to anaesthetic agents. With the advent of newer inhalational agents and changing anaesthetic practices, the risks for anaesthesiologists with regard to adverse reproductive outcomes is unknown. Hence, a nationwide online survey was conducted to study the anaesthetic practices prevalent in India and their association, if any, with poor reproductive outcomes.

Methods: The online survey involved 9974 anaesthesiologists. A questionnaire soliciting information regarding anaesthetic practice techniques, reproductive outcomes and perinatal outcomes was designed. All the anaesthesiologists in the ISA National database were mailed a link to the above questionnaire.

Results: Female anaesthesiologists and spouses of male anaesthesiologists had a higher incidence of first trimester spontaneous abortions than the general population. Female anaesthesiologists when compared with spouses of male anaesthesiologists faced more difficulty with conception (P = 0.015). Female anaesthesiologists who worked in the operating room (OR) in their first trimester of gestation had a higher incidence of spontaneous abortions than those who did not work in the OR (P = 0.05). Longer hours of general anaesthesia conducted in the first trimester of pregnancy was associated with a higher risk of birth defects in their progeny (P = 0.05).

Conclusion: Spontaneous abortions and birth defects were higher in female anaesthesiologists who worked in the OR in the first trimester of gestation. Both female anaesthesiologists and spouses of male anaesthesiologists had a greater risk for a first trimester miscarriage than the general population.

No MeSH data available.


Related in: MedlinePlus