Limits...
Recent Advances in Electrochemical Biosensors Based on Fullerene-C60 Nano-Structured Platforms.

Pilehvar S, De Wael K - Biosensors (Basel) (2015)

Bottom Line: The performance and sensitivity of biosensors is greatly improved with the integration of nanomaterials into their construction.Since its first discovery, fullerene-C60 has been the object of extensive research.We examine the research work reported in the literature on the synthesis, functionalization, approaches to nanostructuring electrodes with fullerene, and outline some of the exciting applications in the field of (bio)sensing.

View Article: PubMed Central - PubMed

Affiliation: AXES Research Group, Department of Chemistry, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium. Sanaz.pilehvar@uantwerpen.be.

ABSTRACT
Nanotechnology is becoming increasingly important in the field of (bio)sensors. The performance and sensitivity of biosensors is greatly improved with the integration of nanomaterials into their construction. Since its first discovery, fullerene-C60 has been the object of extensive research. Its unique and favorable characteristics of easy chemical modification, conductivity, and electrochemical properties has led to its tremendous use in (bio)sensor applications. This paper provides a concise review of advances in fullerene-C60 research and its use as a nanomaterial for the development of biosensors. We examine the research work reported in the literature on the synthesis, functionalization, approaches to nanostructuring electrodes with fullerene, and outline some of the exciting applications in the field of (bio)sensing.

Show MeSH
HOMO and LUMO gap in fullerene-C60.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4697141&req=5

biosensors-05-00712-f002: HOMO and LUMO gap in fullerene-C60.

Mentions: Different biomolecules or organic ligands can be immobilized to the shell of fullerenes by adsorption or covalent attachment [39]. Taking into account that fullerenes are not harmful to biological material and they are small enough, they can locate the closest distance to the active site of biomolecules and easily accept or donate electrons to the species surrounding it and make close arrangements with biomolecules [9,14]. Furhermore, they are an ideal substrate for absorbing energy, taking up electrons and releasing them with ease to a transducer. Their high electron-accepting property is due to a low-lying, triply-degenerate, lowest unoccupied molecular orbital (LUMO) which is around 1.8 eV above its five-fold degenerate highest occupied molecular orbital (HOMO) (Figure 2) [40].


Recent Advances in Electrochemical Biosensors Based on Fullerene-C60 Nano-Structured Platforms.

Pilehvar S, De Wael K - Biosensors (Basel) (2015)

HOMO and LUMO gap in fullerene-C60.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4697141&req=5

biosensors-05-00712-f002: HOMO and LUMO gap in fullerene-C60.
Mentions: Different biomolecules or organic ligands can be immobilized to the shell of fullerenes by adsorption or covalent attachment [39]. Taking into account that fullerenes are not harmful to biological material and they are small enough, they can locate the closest distance to the active site of biomolecules and easily accept or donate electrons to the species surrounding it and make close arrangements with biomolecules [9,14]. Furhermore, they are an ideal substrate for absorbing energy, taking up electrons and releasing them with ease to a transducer. Their high electron-accepting property is due to a low-lying, triply-degenerate, lowest unoccupied molecular orbital (LUMO) which is around 1.8 eV above its five-fold degenerate highest occupied molecular orbital (HOMO) (Figure 2) [40].

Bottom Line: The performance and sensitivity of biosensors is greatly improved with the integration of nanomaterials into their construction.Since its first discovery, fullerene-C60 has been the object of extensive research.We examine the research work reported in the literature on the synthesis, functionalization, approaches to nanostructuring electrodes with fullerene, and outline some of the exciting applications in the field of (bio)sensing.

View Article: PubMed Central - PubMed

Affiliation: AXES Research Group, Department of Chemistry, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium. Sanaz.pilehvar@uantwerpen.be.

ABSTRACT
Nanotechnology is becoming increasingly important in the field of (bio)sensors. The performance and sensitivity of biosensors is greatly improved with the integration of nanomaterials into their construction. Since its first discovery, fullerene-C60 has been the object of extensive research. Its unique and favorable characteristics of easy chemical modification, conductivity, and electrochemical properties has led to its tremendous use in (bio)sensor applications. This paper provides a concise review of advances in fullerene-C60 research and its use as a nanomaterial for the development of biosensors. We examine the research work reported in the literature on the synthesis, functionalization, approaches to nanostructuring electrodes with fullerene, and outline some of the exciting applications in the field of (bio)sensing.

Show MeSH