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Morbus Behçet - a rare disease in Central Europe.

Woźniacka A, Sysa-Jędrzejowska A, Jurowski P, Jabłkowski M, Kot M - Arch Med Sci (2015)

Bottom Line: Frequently a definitive diagnosis is established within several years or months after the first manifestations appear.The increased number of cases, recently described worldwide also in the Polish population, indicates that the disease could spread out of endemic areas.The aim of this manuscript is to present the clinical picture, diagnosis criteria and therapeutic approaches of this "international disease" which currently is observed not only in emigrants from Asia but also in native Polish citizens.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology and Venereology, Medical University of Lodz, Lodz, Poland.

ABSTRACT
Behçet's disease (BD) is a multiorgan inflammatory disease of complex and not entirely elucidated etiology, which was originally diagnosed in patients with aphthous stomatitis, genital ulcerations and ocular manifestations. The entity is endemic in countries of Eastern and Central Asia, especially Turkey and Iran, but rarely seen in Central Europe. As there are no specific diagnostic laboratory tests or histopathologic findings which confirm the preliminary diagnosis, the final diagnosis should be based on clinical criteria. Frequently a definitive diagnosis is established within several years or months after the first manifestations appear. The increased number of cases, recently described worldwide also in the Polish population, indicates that the disease could spread out of endemic areas. The aim of this manuscript is to present the clinical picture, diagnosis criteria and therapeutic approaches of this "international disease" which currently is observed not only in emigrants from Asia but also in native Polish citizens.

No MeSH data available.


Related in: MedlinePlus

Genital ulcers covered with grayish-white fibrinous exudate
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Figure 0003: Genital ulcers covered with grayish-white fibrinous exudate

Mentions: Genital aphthoses are regarded as the most frequent second symptom in the course of the disease. They appear as punched-out, painful lesions with fibrinous exudate on their base (Figures 2, 3). In males, scrotal involvement is most characteristic, but the penile shaft may also be involved. In females, the labial area is most commonly involved, but occasionally the lesions develop in the vagina and on the perineum. Genital ulcerations typically heal with scarring and are more painful in men. Presence of ulcerations in women may correlate with menstruation. Such lesions frequently negatively influence patients’ sexual functioning and psychological state [18]. The term genital ulcers is also described as genital aphthosis. Genital aphthosis frequently occurs in BD and is very suggestive of the diagnosis. According to nationwide surveys performed in Iran, Japan, China, Korea and Germany, genital aphthoses were diagnosed respectively in 65%, 73%, 76%, 83%, and 64% [19].


Morbus Behçet - a rare disease in Central Europe.

Woźniacka A, Sysa-Jędrzejowska A, Jurowski P, Jabłkowski M, Kot M - Arch Med Sci (2015)

Genital ulcers covered with grayish-white fibrinous exudate
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4697052&req=5

Figure 0003: Genital ulcers covered with grayish-white fibrinous exudate
Mentions: Genital aphthoses are regarded as the most frequent second symptom in the course of the disease. They appear as punched-out, painful lesions with fibrinous exudate on their base (Figures 2, 3). In males, scrotal involvement is most characteristic, but the penile shaft may also be involved. In females, the labial area is most commonly involved, but occasionally the lesions develop in the vagina and on the perineum. Genital ulcerations typically heal with scarring and are more painful in men. Presence of ulcerations in women may correlate with menstruation. Such lesions frequently negatively influence patients’ sexual functioning and psychological state [18]. The term genital ulcers is also described as genital aphthosis. Genital aphthosis frequently occurs in BD and is very suggestive of the diagnosis. According to nationwide surveys performed in Iran, Japan, China, Korea and Germany, genital aphthoses were diagnosed respectively in 65%, 73%, 76%, 83%, and 64% [19].

Bottom Line: Frequently a definitive diagnosis is established within several years or months after the first manifestations appear.The increased number of cases, recently described worldwide also in the Polish population, indicates that the disease could spread out of endemic areas.The aim of this manuscript is to present the clinical picture, diagnosis criteria and therapeutic approaches of this "international disease" which currently is observed not only in emigrants from Asia but also in native Polish citizens.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology and Venereology, Medical University of Lodz, Lodz, Poland.

ABSTRACT
Behçet's disease (BD) is a multiorgan inflammatory disease of complex and not entirely elucidated etiology, which was originally diagnosed in patients with aphthous stomatitis, genital ulcerations and ocular manifestations. The entity is endemic in countries of Eastern and Central Asia, especially Turkey and Iran, but rarely seen in Central Europe. As there are no specific diagnostic laboratory tests or histopathologic findings which confirm the preliminary diagnosis, the final diagnosis should be based on clinical criteria. Frequently a definitive diagnosis is established within several years or months after the first manifestations appear. The increased number of cases, recently described worldwide also in the Polish population, indicates that the disease could spread out of endemic areas. The aim of this manuscript is to present the clinical picture, diagnosis criteria and therapeutic approaches of this "international disease" which currently is observed not only in emigrants from Asia but also in native Polish citizens.

No MeSH data available.


Related in: MedlinePlus