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A systematic review and meta-analysis on controlled treatment trials of metacognitive therapy for anxiety disorders.

Sadeghi R, Mokhber N, Mahmoudi LZ, Asgharipour N, Seyfi H - J Res Med Sci (2015)

Bottom Line: We also statistically pooled the results across studies (when possible).The meta-analyses also showed that MCT had statistically significant better results compared to the control groups in GAD (both immediately post-treatment and 12 months post-therapy results), OCD, and PTSD (p-values ranged <0.0001-0.025).Based on the results of our systematic review, MCT seems to be an effective treatment for anxiety disorders and can effectively control their psychological problems.

View Article: PubMed Central - PubMed

Affiliation: Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

ABSTRACT

Background: To conduct a systematic review and meta-analysis on controlled treatment trials of meta-cognitive therapy for anxiety disorders.

Materials and methods: Studies were included if they employed controlled methodology and treated people above 18 years with anxiety disorders. Case studies (with less than 4 cases) and single case designed studies were excluded. A comprehensive literature search identified 15 trials for systematic review.

Results: All included studies showed better treatment results in the MCT arms compared to the control groups. We also statistically pooled the results across studies (when possible). The meta-analyses also showed that MCT had statistically significant better results compared to the control groups in GAD (both immediately post-treatment and 12 months post-therapy results), OCD, and PTSD (p-values ranged <0.0001-0.025).

Conclusion: Based on the results of our systematic review, MCT seems to be an effective treatment for anxiety disorders and can effectively control their psychological problems.

No MeSH data available.


Related in: MedlinePlus

Forrest plot of the difference in means of changes in Metacognitions Questionnaire and Maudsley after metacognitive therapy in Obsessive-Compulsive Disorder
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Figure 3: Forrest plot of the difference in means of changes in Metacognitions Questionnaire and Maudsley after metacognitive therapy in Obsessive-Compulsive Disorder

Mentions: Three studies had enough information for quantitative synthesis of the MCT effect on OCD.[202223] Figure 3 shows the forest plot of the analyses. Standardized differences in means of psychological test score changes were 5.426 (4.272-6.581) (P < 0.00001, Q = 0.5 [P = 0.8], I2 = 0), and 1.835 (1.209-2.46) (P < 0.00001, Q = 25 [P = 0.000001], I2 = 95%) for MCQ global and Maudsley tests, respectively.


A systematic review and meta-analysis on controlled treatment trials of metacognitive therapy for anxiety disorders.

Sadeghi R, Mokhber N, Mahmoudi LZ, Asgharipour N, Seyfi H - J Res Med Sci (2015)

Forrest plot of the difference in means of changes in Metacognitions Questionnaire and Maudsley after metacognitive therapy in Obsessive-Compulsive Disorder
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4696377&req=5

Figure 3: Forrest plot of the difference in means of changes in Metacognitions Questionnaire and Maudsley after metacognitive therapy in Obsessive-Compulsive Disorder
Mentions: Three studies had enough information for quantitative synthesis of the MCT effect on OCD.[202223] Figure 3 shows the forest plot of the analyses. Standardized differences in means of psychological test score changes were 5.426 (4.272-6.581) (P < 0.00001, Q = 0.5 [P = 0.8], I2 = 0), and 1.835 (1.209-2.46) (P < 0.00001, Q = 25 [P = 0.000001], I2 = 95%) for MCQ global and Maudsley tests, respectively.

Bottom Line: We also statistically pooled the results across studies (when possible).The meta-analyses also showed that MCT had statistically significant better results compared to the control groups in GAD (both immediately post-treatment and 12 months post-therapy results), OCD, and PTSD (p-values ranged <0.0001-0.025).Based on the results of our systematic review, MCT seems to be an effective treatment for anxiety disorders and can effectively control their psychological problems.

View Article: PubMed Central - PubMed

Affiliation: Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

ABSTRACT

Background: To conduct a systematic review and meta-analysis on controlled treatment trials of meta-cognitive therapy for anxiety disorders.

Materials and methods: Studies were included if they employed controlled methodology and treated people above 18 years with anxiety disorders. Case studies (with less than 4 cases) and single case designed studies were excluded. A comprehensive literature search identified 15 trials for systematic review.

Results: All included studies showed better treatment results in the MCT arms compared to the control groups. We also statistically pooled the results across studies (when possible). The meta-analyses also showed that MCT had statistically significant better results compared to the control groups in GAD (both immediately post-treatment and 12 months post-therapy results), OCD, and PTSD (p-values ranged <0.0001-0.025).

Conclusion: Based on the results of our systematic review, MCT seems to be an effective treatment for anxiety disorders and can effectively control their psychological problems.

No MeSH data available.


Related in: MedlinePlus