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A systematic review and meta-analysis on controlled treatment trials of metacognitive therapy for anxiety disorders.

Sadeghi R, Mokhber N, Mahmoudi LZ, Asgharipour N, Seyfi H - J Res Med Sci (2015)

Bottom Line: We also statistically pooled the results across studies (when possible).The meta-analyses also showed that MCT had statistically significant better results compared to the control groups in GAD (both immediately post-treatment and 12 months post-therapy results), OCD, and PTSD (p-values ranged <0.0001-0.025).Based on the results of our systematic review, MCT seems to be an effective treatment for anxiety disorders and can effectively control their psychological problems.

View Article: PubMed Central - PubMed

Affiliation: Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

ABSTRACT

Background: To conduct a systematic review and meta-analysis on controlled treatment trials of meta-cognitive therapy for anxiety disorders.

Materials and methods: Studies were included if they employed controlled methodology and treated people above 18 years with anxiety disorders. Case studies (with less than 4 cases) and single case designed studies were excluded. A comprehensive literature search identified 15 trials for systematic review.

Results: All included studies showed better treatment results in the MCT arms compared to the control groups. We also statistically pooled the results across studies (when possible). The meta-analyses also showed that MCT had statistically significant better results compared to the control groups in GAD (both immediately post-treatment and 12 months post-therapy results), OCD, and PTSD (p-values ranged <0.0001-0.025).

Conclusion: Based on the results of our systematic review, MCT seems to be an effective treatment for anxiety disorders and can effectively control their psychological problems.

No MeSH data available.


Related in: MedlinePlus

(a) Forrest plot of the difference in means of changes in Beck Depression Inventory, Beck Anxiety Inventory, and Penn State Worry Questionnaire after metacognitive therapy in generalized anxiety disorders. (b) Forrest plot of difference in means of changes in Beck Depression Inventory, Beck Anxiety Inventory, and Penn State Worry Questionnaire after metacognitive therapy in generalized anxiety disorders for 12-month posttreatment
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Figure 2: (a) Forrest plot of the difference in means of changes in Beck Depression Inventory, Beck Anxiety Inventory, and Penn State Worry Questionnaire after metacognitive therapy in generalized anxiety disorders. (b) Forrest plot of difference in means of changes in Beck Depression Inventory, Beck Anxiety Inventory, and Penn State Worry Questionnaire after metacognitive therapy in generalized anxiety disorders for 12-month posttreatment

Mentions: Three studies had enough information for the quantitative synthesis of MCT effect on GAD.[131819] Figure 2 shows the forest plots of these analyses. Standardized differences in means of psychological test score changes were 7.94 (95% confidence interval: 2.2-13.67) (P = 0.007, Q = 10 [P = 0.01], I2 = 90%), 7.18 (2.2-12.15) (P = 0.005, Q = 9.2 [P = 0.002], I2 = 89%), 7.68 (0.94-14.43) (P = 0.025, Q = 11.5 [P = 0.0006], I2 = 91%) for Penn State Worry Questionnaire (PSWQ), Beck Depression Inventory (BDI), and Beck Anxiety Inventory tests of the posttreatment period. For 12 months posttreatment data the pooled ES were 0.979 (0.616-1.343) (P < 0.00001, Q = 21 [P = 0.00001], I2 = 95%), and 0.633 (0.292-0.975) (P < 0.00001, Q = 5.8 [P = 0.01], I2 = 82%) for PSWQ and BDI, respectively.


A systematic review and meta-analysis on controlled treatment trials of metacognitive therapy for anxiety disorders.

Sadeghi R, Mokhber N, Mahmoudi LZ, Asgharipour N, Seyfi H - J Res Med Sci (2015)

(a) Forrest plot of the difference in means of changes in Beck Depression Inventory, Beck Anxiety Inventory, and Penn State Worry Questionnaire after metacognitive therapy in generalized anxiety disorders. (b) Forrest plot of difference in means of changes in Beck Depression Inventory, Beck Anxiety Inventory, and Penn State Worry Questionnaire after metacognitive therapy in generalized anxiety disorders for 12-month posttreatment
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4696377&req=5

Figure 2: (a) Forrest plot of the difference in means of changes in Beck Depression Inventory, Beck Anxiety Inventory, and Penn State Worry Questionnaire after metacognitive therapy in generalized anxiety disorders. (b) Forrest plot of difference in means of changes in Beck Depression Inventory, Beck Anxiety Inventory, and Penn State Worry Questionnaire after metacognitive therapy in generalized anxiety disorders for 12-month posttreatment
Mentions: Three studies had enough information for the quantitative synthesis of MCT effect on GAD.[131819] Figure 2 shows the forest plots of these analyses. Standardized differences in means of psychological test score changes were 7.94 (95% confidence interval: 2.2-13.67) (P = 0.007, Q = 10 [P = 0.01], I2 = 90%), 7.18 (2.2-12.15) (P = 0.005, Q = 9.2 [P = 0.002], I2 = 89%), 7.68 (0.94-14.43) (P = 0.025, Q = 11.5 [P = 0.0006], I2 = 91%) for Penn State Worry Questionnaire (PSWQ), Beck Depression Inventory (BDI), and Beck Anxiety Inventory tests of the posttreatment period. For 12 months posttreatment data the pooled ES were 0.979 (0.616-1.343) (P < 0.00001, Q = 21 [P = 0.00001], I2 = 95%), and 0.633 (0.292-0.975) (P < 0.00001, Q = 5.8 [P = 0.01], I2 = 82%) for PSWQ and BDI, respectively.

Bottom Line: We also statistically pooled the results across studies (when possible).The meta-analyses also showed that MCT had statistically significant better results compared to the control groups in GAD (both immediately post-treatment and 12 months post-therapy results), OCD, and PTSD (p-values ranged <0.0001-0.025).Based on the results of our systematic review, MCT seems to be an effective treatment for anxiety disorders and can effectively control their psychological problems.

View Article: PubMed Central - PubMed

Affiliation: Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

ABSTRACT

Background: To conduct a systematic review and meta-analysis on controlled treatment trials of meta-cognitive therapy for anxiety disorders.

Materials and methods: Studies were included if they employed controlled methodology and treated people above 18 years with anxiety disorders. Case studies (with less than 4 cases) and single case designed studies were excluded. A comprehensive literature search identified 15 trials for systematic review.

Results: All included studies showed better treatment results in the MCT arms compared to the control groups. We also statistically pooled the results across studies (when possible). The meta-analyses also showed that MCT had statistically significant better results compared to the control groups in GAD (both immediately post-treatment and 12 months post-therapy results), OCD, and PTSD (p-values ranged <0.0001-0.025).

Conclusion: Based on the results of our systematic review, MCT seems to be an effective treatment for anxiety disorders and can effectively control their psychological problems.

No MeSH data available.


Related in: MedlinePlus