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Ketamine administration makes patients and physicians satisfied during gastro-enteric endoscopies.

Majidinejad S, Kajbaf A, Khodadoostan M, Dolatkhah S, Kajbaf MH, Adibi P, Malekmohammad M - J Res Med Sci (2015)

Bottom Line: Therefore, we evaluated the effect of ketamine for sedation in endoscopic procedures of adult patients.Patients who received ketamine had better sedative status (P < 0.001).None of the patients in the case group was completely awake but all of the patients in the control group were awake.

View Article: PubMed Central - PubMed

Affiliation: Department of Emergency Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: A suitable sedative status during gastro-enteric endoscopies results in better physicians' approach and more stable view of internal organs. Therefore, we evaluated the effect of ketamine for sedation in endoscopic procedures of adult patients.

Materials and methods: Patients who were candidates for gastro-enteric endoscopy during the years 2014-2015 were included into the study and divided into two groups of case (administered 5 mg/kg of oral ketamine half an hour before initiation of the procedure) and control (administered placebo in a same pattern). After endoscopy, patients and physicians' satisfaction of sedation was assessed. SPSS-22 was used for data analysis.

Results: Eighty-six patients participated into the study of which divided into each groups. The pain and discomfort scores were 2.4 ± 1.8 and 5.81 ± 1.48 in case and control groups, respectively, (P < 0.001). Mann-Whitney test revealed statistical difference among groups about physician's satisfaction of sedation during endoscopy (P < 0.001). Patients who received ketamine had better sedative status (P < 0.001). None of the patients in the case group was completely awake but all of the patients in the control group were awake. The number of retching during endoscopy showed that individuals in the control group had more frequent retching episodes (P = 0.04).

Conclusion: Low-dose oral administration of ketamine could make a satisfied sedation for gastro-enteric endoscopy.

No MeSH data available.


Related in: MedlinePlus

Severity of pain and nausea in case and control groups
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Figure 1: Severity of pain and nausea in case and control groups

Mentions: Table 2 shows that the mean number of pain severity and discomfort during endoscopy were 2.4 ± 1.8 and 5.81 ± 1.48 in case and control groups, respectively, which showed significant differences among groups (P < 0.001) [Figure 1].


Ketamine administration makes patients and physicians satisfied during gastro-enteric endoscopies.

Majidinejad S, Kajbaf A, Khodadoostan M, Dolatkhah S, Kajbaf MH, Adibi P, Malekmohammad M - J Res Med Sci (2015)

Severity of pain and nausea in case and control groups
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4696371&req=5

Figure 1: Severity of pain and nausea in case and control groups
Mentions: Table 2 shows that the mean number of pain severity and discomfort during endoscopy were 2.4 ± 1.8 and 5.81 ± 1.48 in case and control groups, respectively, which showed significant differences among groups (P < 0.001) [Figure 1].

Bottom Line: Therefore, we evaluated the effect of ketamine for sedation in endoscopic procedures of adult patients.Patients who received ketamine had better sedative status (P < 0.001).None of the patients in the case group was completely awake but all of the patients in the control group were awake.

View Article: PubMed Central - PubMed

Affiliation: Department of Emergency Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: A suitable sedative status during gastro-enteric endoscopies results in better physicians' approach and more stable view of internal organs. Therefore, we evaluated the effect of ketamine for sedation in endoscopic procedures of adult patients.

Materials and methods: Patients who were candidates for gastro-enteric endoscopy during the years 2014-2015 were included into the study and divided into two groups of case (administered 5 mg/kg of oral ketamine half an hour before initiation of the procedure) and control (administered placebo in a same pattern). After endoscopy, patients and physicians' satisfaction of sedation was assessed. SPSS-22 was used for data analysis.

Results: Eighty-six patients participated into the study of which divided into each groups. The pain and discomfort scores were 2.4 ± 1.8 and 5.81 ± 1.48 in case and control groups, respectively, (P < 0.001). Mann-Whitney test revealed statistical difference among groups about physician's satisfaction of sedation during endoscopy (P < 0.001). Patients who received ketamine had better sedative status (P < 0.001). None of the patients in the case group was completely awake but all of the patients in the control group were awake. The number of retching during endoscopy showed that individuals in the control group had more frequent retching episodes (P = 0.04).

Conclusion: Low-dose oral administration of ketamine could make a satisfied sedation for gastro-enteric endoscopy.

No MeSH data available.


Related in: MedlinePlus