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Patient-reported health-related quality of life after a displaced intra-articular calcaneal fracture: a systematic review.

Alexandridis G, Gunning AC, Leenen LP - World J Emerg Surg (2015)

Bottom Line: The identified articles were critically appraised for their relevance and validity.The HRQoL is substantially lower in comparison to the period before the trauma and to the general population, in particular the subdomains related to the physical domain are affected.Consequently, it is challenging to make reliable and valid conclusions.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, University Medical Center Utrecht, Suite: G04.228, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

ABSTRACT

Background: A displaced intra-articular calcaneal fracture (DIACF) is known for having a negative influence on the daily activities of patients. A health-related quality of life (HRQoL) outcome instrument is used to quantify the impact of DIACF. It seems that these studies used restrictive inclusion criteria and observe specific patient groups; consequently, an increased risk of bias that results in incorrect estimation of the impact. Therefore, we will systematically review the current literature.

Materials and methods: A systematic search was performed in PubMed, Embase and Cochrane library. Inclusion criteria were studies reporting DIACF and HRQoL, measured with SF-36, SF-36v2, EQ-5D or EQ-6D. The identified articles were critically appraised for their relevance and validity. The overall risk of bias was determined. The studies with a low to medium risk of bias were used for data extraction.

Results: 32 articles were available for the critical appraisal. 13 articles had a medium risk of bias. All studies reported the SF-36 and two studies also reported the EQ-5D.

Conclusions: This systematic review indicates that DIACF is a life-changing event for most patients. The HRQoL is substantially lower in comparison to the period before the trauma and to the general population, in particular the subdomains related to the physical domain are affected. In addition, this review reveals that the identified studies have a medium to high risk of bias. Consequently, it is challenging to make reliable and valid conclusions. Therefore, we provided recommendations to decrease the risk of bias in order to improve future research.

No MeSH data available.


Related in: MedlinePlus

Flow-chart of search strategy and selection
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Related In: Results  -  Collection

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Fig1: Flow-chart of search strategy and selection

Mentions: At first, all duplicates were excluded. The titles and abstracts of the articles were screened by one reviewer (GA), based on the inclusion criteria (Fig. 1). We have excluded articles that assessed patients who were aged younger than 16 years. In addition, we excluded articles that are reviews. The full text of the remaining articles was screened by two reviewers (GA, ACG). From these articles and the identified systematic reviews, all references were screened using the same criteria. In case of overlapping patient data, the article with the highest number of patients was included.Fig. 1


Patient-reported health-related quality of life after a displaced intra-articular calcaneal fracture: a systematic review.

Alexandridis G, Gunning AC, Leenen LP - World J Emerg Surg (2015)

Flow-chart of search strategy and selection
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4696241&req=5

Fig1: Flow-chart of search strategy and selection
Mentions: At first, all duplicates were excluded. The titles and abstracts of the articles were screened by one reviewer (GA), based on the inclusion criteria (Fig. 1). We have excluded articles that assessed patients who were aged younger than 16 years. In addition, we excluded articles that are reviews. The full text of the remaining articles was screened by two reviewers (GA, ACG). From these articles and the identified systematic reviews, all references were screened using the same criteria. In case of overlapping patient data, the article with the highest number of patients was included.Fig. 1

Bottom Line: The identified articles were critically appraised for their relevance and validity.The HRQoL is substantially lower in comparison to the period before the trauma and to the general population, in particular the subdomains related to the physical domain are affected.Consequently, it is challenging to make reliable and valid conclusions.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, University Medical Center Utrecht, Suite: G04.228, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

ABSTRACT

Background: A displaced intra-articular calcaneal fracture (DIACF) is known for having a negative influence on the daily activities of patients. A health-related quality of life (HRQoL) outcome instrument is used to quantify the impact of DIACF. It seems that these studies used restrictive inclusion criteria and observe specific patient groups; consequently, an increased risk of bias that results in incorrect estimation of the impact. Therefore, we will systematically review the current literature.

Materials and methods: A systematic search was performed in PubMed, Embase and Cochrane library. Inclusion criteria were studies reporting DIACF and HRQoL, measured with SF-36, SF-36v2, EQ-5D or EQ-6D. The identified articles were critically appraised for their relevance and validity. The overall risk of bias was determined. The studies with a low to medium risk of bias were used for data extraction.

Results: 32 articles were available for the critical appraisal. 13 articles had a medium risk of bias. All studies reported the SF-36 and two studies also reported the EQ-5D.

Conclusions: This systematic review indicates that DIACF is a life-changing event for most patients. The HRQoL is substantially lower in comparison to the period before the trauma and to the general population, in particular the subdomains related to the physical domain are affected. In addition, this review reveals that the identified studies have a medium to high risk of bias. Consequently, it is challenging to make reliable and valid conclusions. Therefore, we provided recommendations to decrease the risk of bias in order to improve future research.

No MeSH data available.


Related in: MedlinePlus