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Local anesthetic thoracoscopy for the diagnosis of metastatic pleural melanoma originated from oral malignant melanoma: case report and comments.

Yang B, Li Q, Zhao H, Liu H, Tang T, Jiang C - World J Surg Oncol (2015)

Bottom Line: In this report, we presented a case of metastatic malignant melanoma of the pleura originated from OMM.The patient was therefore diagnosed with metastatic melanoma of the left pleura and the primary melanoma was OMM.According to this case, we could draw the conclusion that pleural metastasis from OMM was very rare and thoracoscopy preceded under local anesthesia is an important method for its accurate diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Thoracic Surgery, Tianjin Union Medicine Centre, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, People's Republic of China. ezxybj@sohu.com.

ABSTRACT

Background: Oral malignant melanoma (OMM) is an aggressive tumor with very low survival rate and easy to metastasize. Pleural metastatic melanoma via primary OMM is rare.

Case presentation: In this report, we presented a case of metastatic malignant melanoma of the pleura originated from OMM. A 54-year-old man without primary skin lesion was diagnosed multiple nodular shadows, pleural invasion, and pleural effusion by chest computed tomography (CT). One cyst-form tumor on the tongue base was observed by bronchoscopy, which was diagnosed as OMM by pathological examination and then was resected. After getting the tumor tissues from the pleura by pleural biopsy surgery, the diagnosis of pathological examination was pleural metastatic melanoma. Furthermore, tumor cells displayed a positive immunoreaction for melanocytic markers S100 and HMB-45 combining with positive vimentin and cytokeratin AE1/AE3. The patient was therefore diagnosed with metastatic melanoma of the left pleura and the primary melanoma was OMM.

Conclusions: According to this case, we could draw the conclusion that pleural metastasis from OMM was very rare and thoracoscopy preceded under local anesthesia is an important method for its accurate diagnosis.

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Related in: MedlinePlus

The main observation of pleural biopsy surgery in the right parietal pleura. Multiple violet-black neoplasms can be seen in the parietal pleura by thoracoscopy with video assistance, being different sizes, very brittle, and prone to bleeding, and these lesions are pointed by white arrows (a–c). d The tumor tissues were gained by biopsy forceps. The used forceps is pointed by blue arrow
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Fig5: The main observation of pleural biopsy surgery in the right parietal pleura. Multiple violet-black neoplasms can be seen in the parietal pleura by thoracoscopy with video assistance, being different sizes, very brittle, and prone to bleeding, and these lesions are pointed by white arrows (a–c). d The tumor tissues were gained by biopsy forceps. The used forceps is pointed by blue arrow

Mentions: Subsequently, the pleural biopsy surgery of the left thorax was preceded by semi-rigid thoracoscopy (model LTF-240, Olympus, Tokyo, Japan) (Fig. 4) with video assistance under local anesthesia using 10 mL 1 % Lidocaine injected into the subcutaneous tissue. The thoracoscopy was entered from a single port in the sixth intercostal space. After extraction of 1500 mL bloody pleural fluid, multiple violet black neoplasms can be seen in the parietal pleura, which were different sizes, very brittle, and prone to bleeding (Fig. 5). After biting from several sections of these lesions, the tissues were used for pathological detection. Pleural effusion was continuously discharged by using closed drainage tube. Cytology examination of pleural effusion displayed red blood cells in the field of vision and severe abnormity of cell nucleus.Fig. 4


Local anesthetic thoracoscopy for the diagnosis of metastatic pleural melanoma originated from oral malignant melanoma: case report and comments.

Yang B, Li Q, Zhao H, Liu H, Tang T, Jiang C - World J Surg Oncol (2015)

The main observation of pleural biopsy surgery in the right parietal pleura. Multiple violet-black neoplasms can be seen in the parietal pleura by thoracoscopy with video assistance, being different sizes, very brittle, and prone to bleeding, and these lesions are pointed by white arrows (a–c). d The tumor tissues were gained by biopsy forceps. The used forceps is pointed by blue arrow
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4666196&req=5

Fig5: The main observation of pleural biopsy surgery in the right parietal pleura. Multiple violet-black neoplasms can be seen in the parietal pleura by thoracoscopy with video assistance, being different sizes, very brittle, and prone to bleeding, and these lesions are pointed by white arrows (a–c). d The tumor tissues were gained by biopsy forceps. The used forceps is pointed by blue arrow
Mentions: Subsequently, the pleural biopsy surgery of the left thorax was preceded by semi-rigid thoracoscopy (model LTF-240, Olympus, Tokyo, Japan) (Fig. 4) with video assistance under local anesthesia using 10 mL 1 % Lidocaine injected into the subcutaneous tissue. The thoracoscopy was entered from a single port in the sixth intercostal space. After extraction of 1500 mL bloody pleural fluid, multiple violet black neoplasms can be seen in the parietal pleura, which were different sizes, very brittle, and prone to bleeding (Fig. 5). After biting from several sections of these lesions, the tissues were used for pathological detection. Pleural effusion was continuously discharged by using closed drainage tube. Cytology examination of pleural effusion displayed red blood cells in the field of vision and severe abnormity of cell nucleus.Fig. 4

Bottom Line: In this report, we presented a case of metastatic malignant melanoma of the pleura originated from OMM.The patient was therefore diagnosed with metastatic melanoma of the left pleura and the primary melanoma was OMM.According to this case, we could draw the conclusion that pleural metastasis from OMM was very rare and thoracoscopy preceded under local anesthesia is an important method for its accurate diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Thoracic Surgery, Tianjin Union Medicine Centre, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, People's Republic of China. ezxybj@sohu.com.

ABSTRACT

Background: Oral malignant melanoma (OMM) is an aggressive tumor with very low survival rate and easy to metastasize. Pleural metastatic melanoma via primary OMM is rare.

Case presentation: In this report, we presented a case of metastatic malignant melanoma of the pleura originated from OMM. A 54-year-old man without primary skin lesion was diagnosed multiple nodular shadows, pleural invasion, and pleural effusion by chest computed tomography (CT). One cyst-form tumor on the tongue base was observed by bronchoscopy, which was diagnosed as OMM by pathological examination and then was resected. After getting the tumor tissues from the pleura by pleural biopsy surgery, the diagnosis of pathological examination was pleural metastatic melanoma. Furthermore, tumor cells displayed a positive immunoreaction for melanocytic markers S100 and HMB-45 combining with positive vimentin and cytokeratin AE1/AE3. The patient was therefore diagnosed with metastatic melanoma of the left pleura and the primary melanoma was OMM.

Conclusions: According to this case, we could draw the conclusion that pleural metastasis from OMM was very rare and thoracoscopy preceded under local anesthesia is an important method for its accurate diagnosis.

Show MeSH
Related in: MedlinePlus