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Cytological diagnosis of bancroftian filariasis presented as a subcutaneous swelling in the cubital fossa: an unusual presentation.

Pandey P, Dixit A, Chandra S, Tanwar A - Oxf Med Case Reports (2015)

Bottom Line: Filariasis is a disabling parasitic disease and the prevalence of lymphatic filariasis caused by Wuchereria bancrofti is quite high in India.Indirect ELISA was highly positive for specific recombinant W. bancrofti filarial antigen (WL-L2).The role of cytology cannot be underestimated in clinically unanticipated cases of bancroftian filariasis, especially with the amicrofilaremic state.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Pathology , U.P. Rural Institute of Medical Sciences and Research , Saifai, Uttar Pradesh , India.

ABSTRACT
Filariasis is a disabling parasitic disease and the prevalence of lymphatic filariasis caused by Wuchereria bancrofti is quite high in India. However, W. bancrofti presenting as a subcutaneous swelling and a demonstration of microfilariae in cytological smears from upper extremity lesions is extremely rare. We report a case of 20-year-old male who presented with a small subcutaneous swelling near medial aspect of the left cubital fossa. The wet mount preparation showed many motile microfilariae. Cytology smears revealed a large number of sheathed microfilariae with the tail tip free of nucleus, identified as W. bancrofti without significant inflammatory cell infiltrate. Indirect ELISA was highly positive for specific recombinant W. bancrofti filarial antigen (WL-L2). The role of cytology cannot be underestimated in clinically unanticipated cases of bancroftian filariasis, especially with the amicrofilaremic state. Filariasis should always be considered in the differential diagnosis during cytological evaluation of any swelling, especially in endemic areas.

No MeSH data available.


Related in: MedlinePlus

A small subcutaneous swelling near medial aspect of the left cubital fossa.
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OMV027F1: A small subcutaneous swelling near medial aspect of the left cubital fossa.

Mentions: A 20-year-old male, resident of Saifai village of Etawah district, Uttar Pradesh, India, presented in the Surgery Out-patient Department with a small swelling near medial aspect of the left cubital fossa since 2 months. There was no history of pain, trauma, discharge or a rapid increase in size of the swelling. On local examination, a small subcutaneous, slightly elongated, soft, non-tender and cystic swelling of size 2 x 1 cm, and without any fixity to deeper tissue was observed (Fig. 1). The patient was referred to Pathology Department for FNAC with a clinical diagnosis of benign soft tissue neoplasm. One milliliter of clear fluid was aspirated. The wet mount preparation and the smears made from the fluid were studied microscopically.Figure 1:


Cytological diagnosis of bancroftian filariasis presented as a subcutaneous swelling in the cubital fossa: an unusual presentation.

Pandey P, Dixit A, Chandra S, Tanwar A - Oxf Med Case Reports (2015)

A small subcutaneous swelling near medial aspect of the left cubital fossa.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4664843&req=5

OMV027F1: A small subcutaneous swelling near medial aspect of the left cubital fossa.
Mentions: A 20-year-old male, resident of Saifai village of Etawah district, Uttar Pradesh, India, presented in the Surgery Out-patient Department with a small swelling near medial aspect of the left cubital fossa since 2 months. There was no history of pain, trauma, discharge or a rapid increase in size of the swelling. On local examination, a small subcutaneous, slightly elongated, soft, non-tender and cystic swelling of size 2 x 1 cm, and without any fixity to deeper tissue was observed (Fig. 1). The patient was referred to Pathology Department for FNAC with a clinical diagnosis of benign soft tissue neoplasm. One milliliter of clear fluid was aspirated. The wet mount preparation and the smears made from the fluid were studied microscopically.Figure 1:

Bottom Line: Filariasis is a disabling parasitic disease and the prevalence of lymphatic filariasis caused by Wuchereria bancrofti is quite high in India.Indirect ELISA was highly positive for specific recombinant W. bancrofti filarial antigen (WL-L2).The role of cytology cannot be underestimated in clinically unanticipated cases of bancroftian filariasis, especially with the amicrofilaremic state.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Pathology , U.P. Rural Institute of Medical Sciences and Research , Saifai, Uttar Pradesh , India.

ABSTRACT
Filariasis is a disabling parasitic disease and the prevalence of lymphatic filariasis caused by Wuchereria bancrofti is quite high in India. However, W. bancrofti presenting as a subcutaneous swelling and a demonstration of microfilariae in cytological smears from upper extremity lesions is extremely rare. We report a case of 20-year-old male who presented with a small subcutaneous swelling near medial aspect of the left cubital fossa. The wet mount preparation showed many motile microfilariae. Cytology smears revealed a large number of sheathed microfilariae with the tail tip free of nucleus, identified as W. bancrofti without significant inflammatory cell infiltrate. Indirect ELISA was highly positive for specific recombinant W. bancrofti filarial antigen (WL-L2). The role of cytology cannot be underestimated in clinically unanticipated cases of bancroftian filariasis, especially with the amicrofilaremic state. Filariasis should always be considered in the differential diagnosis during cytological evaluation of any swelling, especially in endemic areas.

No MeSH data available.


Related in: MedlinePlus