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Transcriptional profiling of differentially expressed long non-coding RNAs in breast cancer.

Wang L, Shen X, Xie B, Ma Z, Chen X, Cao F - Genom Data (2015)

Bottom Line: However, little is known about their mechanistic role in breast cancer pathogenesis, especially in triple-negative breast carcinomas (TNBC) that have particular poor outcomes.The basic analysis as contained in the manuscript published in Oncotarget with the PMID 26078338.These data can be used to further elucidate the mechanisms of breast cancer.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Taizhou Hospital, Wenzhou Medical University, Taizhou, Zhejiang, China.

ABSTRACT
Long non-coding RNAs (lncRNAs) are subclass of noncoding RNAs that have been recently shown to play critical roles in cancer biology. However, little is known about their mechanistic role in breast cancer pathogenesis, especially in triple-negative breast carcinomas (TNBC) that have particular poor outcomes. This study was specifically designed to identify the signatures relevant lncRNAs in breast cancer and characterize lncRNAs that modulate the phenotype. Here we provide detailed methods and analysis of microarray data, which is deposited in the Gene Expression Omnibus (GEO) with the accession number GSE64790. The basic analysis as contained in the manuscript published in Oncotarget with the PMID 26078338. These data can be used to further elucidate the mechanisms of breast cancer.

No MeSH data available.


Related in: MedlinePlus

Immunochemical staining of estrogen receptor/progesterone receptor and ErbB2 receptor of 3 TNBC samples for microarray analysis.
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f0005: Immunochemical staining of estrogen receptor/progesterone receptor and ErbB2 receptor of 3 TNBC samples for microarray analysis.

Mentions: All patients are informed and have declared written informed consent that their samples can be used for research. All patients received tumor resection at Zhejiang Taizhou Hospital and were diagnosed with TNBC histopathologically after surgery. Immunochemical staining of estrogen receptor/progesterone receptor and ErbB2 receptor in 3 samples are shown in Fig. 1. There was no radiotherapy or chemotherapy prior to surgery. 3 paired samples were used for microarray analysis of lncRNAs. Demographic and clinical characterizations of the study population are summarized in Table 1.


Transcriptional profiling of differentially expressed long non-coding RNAs in breast cancer.

Wang L, Shen X, Xie B, Ma Z, Chen X, Cao F - Genom Data (2015)

Immunochemical staining of estrogen receptor/progesterone receptor and ErbB2 receptor of 3 TNBC samples for microarray analysis.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4664755&req=5

f0005: Immunochemical staining of estrogen receptor/progesterone receptor and ErbB2 receptor of 3 TNBC samples for microarray analysis.
Mentions: All patients are informed and have declared written informed consent that their samples can be used for research. All patients received tumor resection at Zhejiang Taizhou Hospital and were diagnosed with TNBC histopathologically after surgery. Immunochemical staining of estrogen receptor/progesterone receptor and ErbB2 receptor in 3 samples are shown in Fig. 1. There was no radiotherapy or chemotherapy prior to surgery. 3 paired samples were used for microarray analysis of lncRNAs. Demographic and clinical characterizations of the study population are summarized in Table 1.

Bottom Line: However, little is known about their mechanistic role in breast cancer pathogenesis, especially in triple-negative breast carcinomas (TNBC) that have particular poor outcomes.The basic analysis as contained in the manuscript published in Oncotarget with the PMID 26078338.These data can be used to further elucidate the mechanisms of breast cancer.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Taizhou Hospital, Wenzhou Medical University, Taizhou, Zhejiang, China.

ABSTRACT
Long non-coding RNAs (lncRNAs) are subclass of noncoding RNAs that have been recently shown to play critical roles in cancer biology. However, little is known about their mechanistic role in breast cancer pathogenesis, especially in triple-negative breast carcinomas (TNBC) that have particular poor outcomes. This study was specifically designed to identify the signatures relevant lncRNAs in breast cancer and characterize lncRNAs that modulate the phenotype. Here we provide detailed methods and analysis of microarray data, which is deposited in the Gene Expression Omnibus (GEO) with the accession number GSE64790. The basic analysis as contained in the manuscript published in Oncotarget with the PMID 26078338. These data can be used to further elucidate the mechanisms of breast cancer.

No MeSH data available.


Related in: MedlinePlus