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Age-Related Inter-Region EEG Coupling Changes During the Control of Bottom-Up and Top-Down Attention.

Li L, Zhao D - Front Aging Neurosci (2015)

Bottom Line: Specifically, prefronto-frontal coupling in theta- and alpha-bands, fronto-parietal and parieto-occipital couplings in beta-band for younger group showed a right hemispheric dominance, which was reduced with aging to compensate for the inhibitory dysfunction.While pop-out target detection was mainly associated with greater parieto-occipital beta-coupling strength compared to search condition regardless of aging.Taken together these findings provide evidence that prefronto-frontal coupling of theta-, alpha-, and beta-bands may serve as a possible basis of aging during visual attention, while parieto-occipital coupling in beta-band could serve for a bottom-up function and be vulnerable to top-down attention control for younger and older groups.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China Chengdu, China.

ABSTRACT
We investigated age-related changes in electroencephalographic (EEG) coupling of theta-, alpha-, and beta-frequency bands during bottom-up and top-down attention. Arrays were presented with either automatic "pop-out" (bottom-up) or effortful "search" (top-down) behavior to younger and older participants. The phase-locking value was used to estimate coupling strength between scalp recordings. Behavioral performance decreased with age, with a greater age-related decline in accuracy for the search than for the pop-out condition. Aging was associated with a declined coupling strength of theta and alpha frequency bands, with a greater age-related decline in whole-brain coupling values for the search than for the pop-out condition. Specifically, prefronto-frontal coupling in theta- and alpha-bands, fronto-parietal and parieto-occipital couplings in beta-band for younger group showed a right hemispheric dominance, which was reduced with aging to compensate for the inhibitory dysfunction. While pop-out target detection was mainly associated with greater parieto-occipital beta-coupling strength compared to search condition regardless of aging. Furthermore, prefronto-frontal coupling in theta-, alpha-, and beta-bands, and parieto-occipital coupling in beta-band functioned as predictors of behavior for both groups. Taken together these findings provide evidence that prefronto-frontal coupling of theta-, alpha-, and beta-bands may serve as a possible basis of aging during visual attention, while parieto-occipital coupling in beta-band could serve for a bottom-up function and be vulnerable to top-down attention control for younger and older groups.

No MeSH data available.


Related in: MedlinePlus

(A) Inter-regions coupling in beta frequency band. Blue lines indicate main effect of age (younger > older) and red line indicates main effect of condition (pop-out > search). (B) Linear negative regression between mean RT and coupling value between left central-parietal and parietal-occipital regions for the pop-out condition with the left field target in the younger group. Linear positive regression between mean accuracy and coupling value between left central-parietal and parietal-occipital regions for the search condition with the right target in the younger group (C) and for the pop-out condition with the left target in the older group (D). Linear positive regression between mean accuracy and coupling value between right central-parietal and parietal-occipital regions for the pop-out condition with the right target (E) and the left target (F) in the older group.
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Figure 6: (A) Inter-regions coupling in beta frequency band. Blue lines indicate main effect of age (younger > older) and red line indicates main effect of condition (pop-out > search). (B) Linear negative regression between mean RT and coupling value between left central-parietal and parietal-occipital regions for the pop-out condition with the left field target in the younger group. Linear positive regression between mean accuracy and coupling value between left central-parietal and parietal-occipital regions for the search condition with the right target in the younger group (C) and for the pop-out condition with the left target in the older group (D). Linear positive regression between mean accuracy and coupling value between right central-parietal and parietal-occipital regions for the pop-out condition with the right target (E) and the left target (F) in the older group.

Mentions: Figures 5A and 6A summarizes the main effect of age and condition among eight regions of interest. As can be seen in Figure 5A with blue lines, there was a main effect of age for coupling values on two long range connections, including the connections between left prefrontal and left central-frontal regions [1 and 3, F(1,24) = 5.49, p = 0.03], between right prefrontal and right central-frontal regions [2 and 4, F(1,24) = 5.03, p = 0.03], with smaller coupling values for older subjects. In addition, there was a main effect of condition for those two frontal connections [1 and 3, F(1,24) = 4.46, p = 0.045; 2 and 4, F(1,24) = 7.26, p = 0.01] marked with red lines in Figure 5A, with smaller coupling values in search condition. There was a main effect of condition for coupling values between left central-frontal and left central-parietal regions [3 and 5, F(1,24) = 4.87, p = 0.04], between right central-frontal and right central-parietal regions [4 and 6, F(1,24) = 5.96, p = 0.02], between left central-parietal and left parietal-occipital [5 and 7, F(1,24) = 5.81, p = 0.02], between right central-parietal and right parieto-occipital regions [6 and 8, F(1,24) = 7.75, p = 0.01], with smaller coupling values in search condition (Figure 5A).


Age-Related Inter-Region EEG Coupling Changes During the Control of Bottom-Up and Top-Down Attention.

Li L, Zhao D - Front Aging Neurosci (2015)

(A) Inter-regions coupling in beta frequency band. Blue lines indicate main effect of age (younger > older) and red line indicates main effect of condition (pop-out > search). (B) Linear negative regression between mean RT and coupling value between left central-parietal and parietal-occipital regions for the pop-out condition with the left field target in the younger group. Linear positive regression between mean accuracy and coupling value between left central-parietal and parietal-occipital regions for the search condition with the right target in the younger group (C) and for the pop-out condition with the left target in the older group (D). Linear positive regression between mean accuracy and coupling value between right central-parietal and parietal-occipital regions for the pop-out condition with the right target (E) and the left target (F) in the older group.
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Figure 6: (A) Inter-regions coupling in beta frequency band. Blue lines indicate main effect of age (younger > older) and red line indicates main effect of condition (pop-out > search). (B) Linear negative regression between mean RT and coupling value between left central-parietal and parietal-occipital regions for the pop-out condition with the left field target in the younger group. Linear positive regression between mean accuracy and coupling value between left central-parietal and parietal-occipital regions for the search condition with the right target in the younger group (C) and for the pop-out condition with the left target in the older group (D). Linear positive regression between mean accuracy and coupling value between right central-parietal and parietal-occipital regions for the pop-out condition with the right target (E) and the left target (F) in the older group.
Mentions: Figures 5A and 6A summarizes the main effect of age and condition among eight regions of interest. As can be seen in Figure 5A with blue lines, there was a main effect of age for coupling values on two long range connections, including the connections between left prefrontal and left central-frontal regions [1 and 3, F(1,24) = 5.49, p = 0.03], between right prefrontal and right central-frontal regions [2 and 4, F(1,24) = 5.03, p = 0.03], with smaller coupling values for older subjects. In addition, there was a main effect of condition for those two frontal connections [1 and 3, F(1,24) = 4.46, p = 0.045; 2 and 4, F(1,24) = 7.26, p = 0.01] marked with red lines in Figure 5A, with smaller coupling values in search condition. There was a main effect of condition for coupling values between left central-frontal and left central-parietal regions [3 and 5, F(1,24) = 4.87, p = 0.04], between right central-frontal and right central-parietal regions [4 and 6, F(1,24) = 5.96, p = 0.02], between left central-parietal and left parietal-occipital [5 and 7, F(1,24) = 5.81, p = 0.02], between right central-parietal and right parieto-occipital regions [6 and 8, F(1,24) = 7.75, p = 0.01], with smaller coupling values in search condition (Figure 5A).

Bottom Line: Specifically, prefronto-frontal coupling in theta- and alpha-bands, fronto-parietal and parieto-occipital couplings in beta-band for younger group showed a right hemispheric dominance, which was reduced with aging to compensate for the inhibitory dysfunction.While pop-out target detection was mainly associated with greater parieto-occipital beta-coupling strength compared to search condition regardless of aging.Taken together these findings provide evidence that prefronto-frontal coupling of theta-, alpha-, and beta-bands may serve as a possible basis of aging during visual attention, while parieto-occipital coupling in beta-band could serve for a bottom-up function and be vulnerable to top-down attention control for younger and older groups.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China Chengdu, China.

ABSTRACT
We investigated age-related changes in electroencephalographic (EEG) coupling of theta-, alpha-, and beta-frequency bands during bottom-up and top-down attention. Arrays were presented with either automatic "pop-out" (bottom-up) or effortful "search" (top-down) behavior to younger and older participants. The phase-locking value was used to estimate coupling strength between scalp recordings. Behavioral performance decreased with age, with a greater age-related decline in accuracy for the search than for the pop-out condition. Aging was associated with a declined coupling strength of theta and alpha frequency bands, with a greater age-related decline in whole-brain coupling values for the search than for the pop-out condition. Specifically, prefronto-frontal coupling in theta- and alpha-bands, fronto-parietal and parieto-occipital couplings in beta-band for younger group showed a right hemispheric dominance, which was reduced with aging to compensate for the inhibitory dysfunction. While pop-out target detection was mainly associated with greater parieto-occipital beta-coupling strength compared to search condition regardless of aging. Furthermore, prefronto-frontal coupling in theta-, alpha-, and beta-bands, and parieto-occipital coupling in beta-band functioned as predictors of behavior for both groups. Taken together these findings provide evidence that prefronto-frontal coupling of theta-, alpha-, and beta-bands may serve as a possible basis of aging during visual attention, while parieto-occipital coupling in beta-band could serve for a bottom-up function and be vulnerable to top-down attention control for younger and older groups.

No MeSH data available.


Related in: MedlinePlus