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Age-Related Inter-Region EEG Coupling Changes During the Control of Bottom-Up and Top-Down Attention.

Li L, Zhao D - Front Aging Neurosci (2015)

Bottom Line: Specifically, prefronto-frontal coupling in theta- and alpha-bands, fronto-parietal and parieto-occipital couplings in beta-band for younger group showed a right hemispheric dominance, which was reduced with aging to compensate for the inhibitory dysfunction.While pop-out target detection was mainly associated with greater parieto-occipital beta-coupling strength compared to search condition regardless of aging.Taken together these findings provide evidence that prefronto-frontal coupling of theta-, alpha-, and beta-bands may serve as a possible basis of aging during visual attention, while parieto-occipital coupling in beta-band could serve for a bottom-up function and be vulnerable to top-down attention control for younger and older groups.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China Chengdu, China.

ABSTRACT
We investigated age-related changes in electroencephalographic (EEG) coupling of theta-, alpha-, and beta-frequency bands during bottom-up and top-down attention. Arrays were presented with either automatic "pop-out" (bottom-up) or effortful "search" (top-down) behavior to younger and older participants. The phase-locking value was used to estimate coupling strength between scalp recordings. Behavioral performance decreased with age, with a greater age-related decline in accuracy for the search than for the pop-out condition. Aging was associated with a declined coupling strength of theta and alpha frequency bands, with a greater age-related decline in whole-brain coupling values for the search than for the pop-out condition. Specifically, prefronto-frontal coupling in theta- and alpha-bands, fronto-parietal and parieto-occipital couplings in beta-band for younger group showed a right hemispheric dominance, which was reduced with aging to compensate for the inhibitory dysfunction. While pop-out target detection was mainly associated with greater parieto-occipital beta-coupling strength compared to search condition regardless of aging. Furthermore, prefronto-frontal coupling in theta-, alpha-, and beta-bands, and parieto-occipital coupling in beta-band functioned as predictors of behavior for both groups. Taken together these findings provide evidence that prefronto-frontal coupling of theta-, alpha-, and beta-bands may serve as a possible basis of aging during visual attention, while parieto-occipital coupling in beta-band could serve for a bottom-up function and be vulnerable to top-down attention control for younger and older groups.

No MeSH data available.


Related in: MedlinePlus

Eight regions of interest (ROIs, marked by red rectangles) for inter-region analysis were selected including left prefrontal (Fp1, AF7, AF3, F5, F3, F1), right prefrontal (Fp2, AF8, AF4, F6, F4, F2), Left central-frontal (FC5, FC3, FC1, C5, C3, C1), right central-frontal (FC6, FC4, FC2, C6, C4, C2), Left central-parietal (CP5, CP3, CP1, P5, P3, P1), right central-parietal (CP6, CP4, CP2, P6, P4, P2), Left parietal-occipital (PO7, PO3, O1), and right parieto-occipital (PO8, PO4, O2) regions.
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Figure 2: Eight regions of interest (ROIs, marked by red rectangles) for inter-region analysis were selected including left prefrontal (Fp1, AF7, AF3, F5, F3, F1), right prefrontal (Fp2, AF8, AF4, F6, F4, F2), Left central-frontal (FC5, FC3, FC1, C5, C3, C1), right central-frontal (FC6, FC4, FC2, C6, C4, C2), Left central-parietal (CP5, CP3, CP1, P5, P3, P1), right central-parietal (CP6, CP4, CP2, P6, P4, P2), Left parietal-occipital (PO7, PO3, O1), and right parieto-occipital (PO8, PO4, O2) regions.

Mentions: Eight regions of interest (ROIs) were selected including left prefrontal (Fp1, AF7, AF3, F5, F3, F1), right prefrontal (Fp2, AF8, AF4, F6, F4, F2), left central-frontal (FC5, FC3, FC1, C5, C3, C1), right central-frontal (FC6, FC4, FC2, C6, C4, C2), left central-parietal (CP5, CP3, CP1, P5, P3, P1), right central-parietal (CP6, CP4, CP2, P6, P4, P2), left parietal-occipital (PO7, PO3, O1), and right parieto-occipital (PO8, PO4, O2) regions (see Figure 2). Max normalized PLV values for all pair-wise combinations of eight regions of interest were calculated, generating 28 (totally 8 ROIs) index values for frequency bands of interest in four conditions for both groups. With α = 0.05 and N = 28 comparisons, an index value greater than 2.91 was required for significance by Bonferroni correction for multiple comparisons. Each significant connectivity between ROIs were then analyzed with a repeated measure ANOVA with condition (pop-out and search) and target visual field (left and right) as the within-subject factors and age (young and old) as the between-subject factor for frequency bands of interest.


Age-Related Inter-Region EEG Coupling Changes During the Control of Bottom-Up and Top-Down Attention.

Li L, Zhao D - Front Aging Neurosci (2015)

Eight regions of interest (ROIs, marked by red rectangles) for inter-region analysis were selected including left prefrontal (Fp1, AF7, AF3, F5, F3, F1), right prefrontal (Fp2, AF8, AF4, F6, F4, F2), Left central-frontal (FC5, FC3, FC1, C5, C3, C1), right central-frontal (FC6, FC4, FC2, C6, C4, C2), Left central-parietal (CP5, CP3, CP1, P5, P3, P1), right central-parietal (CP6, CP4, CP2, P6, P4, P2), Left parietal-occipital (PO7, PO3, O1), and right parieto-occipital (PO8, PO4, O2) regions.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4664751&req=5

Figure 2: Eight regions of interest (ROIs, marked by red rectangles) for inter-region analysis were selected including left prefrontal (Fp1, AF7, AF3, F5, F3, F1), right prefrontal (Fp2, AF8, AF4, F6, F4, F2), Left central-frontal (FC5, FC3, FC1, C5, C3, C1), right central-frontal (FC6, FC4, FC2, C6, C4, C2), Left central-parietal (CP5, CP3, CP1, P5, P3, P1), right central-parietal (CP6, CP4, CP2, P6, P4, P2), Left parietal-occipital (PO7, PO3, O1), and right parieto-occipital (PO8, PO4, O2) regions.
Mentions: Eight regions of interest (ROIs) were selected including left prefrontal (Fp1, AF7, AF3, F5, F3, F1), right prefrontal (Fp2, AF8, AF4, F6, F4, F2), left central-frontal (FC5, FC3, FC1, C5, C3, C1), right central-frontal (FC6, FC4, FC2, C6, C4, C2), left central-parietal (CP5, CP3, CP1, P5, P3, P1), right central-parietal (CP6, CP4, CP2, P6, P4, P2), left parietal-occipital (PO7, PO3, O1), and right parieto-occipital (PO8, PO4, O2) regions (see Figure 2). Max normalized PLV values for all pair-wise combinations of eight regions of interest were calculated, generating 28 (totally 8 ROIs) index values for frequency bands of interest in four conditions for both groups. With α = 0.05 and N = 28 comparisons, an index value greater than 2.91 was required for significance by Bonferroni correction for multiple comparisons. Each significant connectivity between ROIs were then analyzed with a repeated measure ANOVA with condition (pop-out and search) and target visual field (left and right) as the within-subject factors and age (young and old) as the between-subject factor for frequency bands of interest.

Bottom Line: Specifically, prefronto-frontal coupling in theta- and alpha-bands, fronto-parietal and parieto-occipital couplings in beta-band for younger group showed a right hemispheric dominance, which was reduced with aging to compensate for the inhibitory dysfunction.While pop-out target detection was mainly associated with greater parieto-occipital beta-coupling strength compared to search condition regardless of aging.Taken together these findings provide evidence that prefronto-frontal coupling of theta-, alpha-, and beta-bands may serve as a possible basis of aging during visual attention, while parieto-occipital coupling in beta-band could serve for a bottom-up function and be vulnerable to top-down attention control for younger and older groups.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China Chengdu, China.

ABSTRACT
We investigated age-related changes in electroencephalographic (EEG) coupling of theta-, alpha-, and beta-frequency bands during bottom-up and top-down attention. Arrays were presented with either automatic "pop-out" (bottom-up) or effortful "search" (top-down) behavior to younger and older participants. The phase-locking value was used to estimate coupling strength between scalp recordings. Behavioral performance decreased with age, with a greater age-related decline in accuracy for the search than for the pop-out condition. Aging was associated with a declined coupling strength of theta and alpha frequency bands, with a greater age-related decline in whole-brain coupling values for the search than for the pop-out condition. Specifically, prefronto-frontal coupling in theta- and alpha-bands, fronto-parietal and parieto-occipital couplings in beta-band for younger group showed a right hemispheric dominance, which was reduced with aging to compensate for the inhibitory dysfunction. While pop-out target detection was mainly associated with greater parieto-occipital beta-coupling strength compared to search condition regardless of aging. Furthermore, prefronto-frontal coupling in theta-, alpha-, and beta-bands, and parieto-occipital coupling in beta-band functioned as predictors of behavior for both groups. Taken together these findings provide evidence that prefronto-frontal coupling of theta-, alpha-, and beta-bands may serve as a possible basis of aging during visual attention, while parieto-occipital coupling in beta-band could serve for a bottom-up function and be vulnerable to top-down attention control for younger and older groups.

No MeSH data available.


Related in: MedlinePlus