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From Theory to PrACTice: A Cognitive Remediation Program Based on a Neuropsychological Model of Schizophrenia.

Fabre D, Vehier A, Chesnoy-Servanin G, Gouiller N, D'Amato T, Saoud M - Front Psychiatry (2015)

Bottom Line: However, moderate improvement for patients who benefit from these therapies has been observed as described in Wykes et al. review (3).Interestingly, available cognitive remediation programs have not been influenced by these models.We describe the PrACTice program that is in the process of being validated.

View Article: PubMed Central - PubMed

Affiliation: EA 4615, Centre Hospitalier le Vinatier, Université de Lyon , Bron , France.

ABSTRACT
Cognitive dysfunction is one of the hallmark deficits of schizophrenia. A wide range of studies illustrate how it is strongly interconnected to clinical presentation and daily life functioning [see Ref. (1, 2)]. Hence, cognition is an important treatment target in schizophrenia. To address the challenge of cognitive enhancement in schizophrenia, a large number of cognitive remediation programs have been developed and evaluated over the past several decades. First, an overview of these programs is presented highlighting their specificity to cognitive deficit in schizophrenia using an integrated method. In this case, cognitive training focuses on enhancing several elementary cognitive functions considered as a prerequisite to social skills or vocational training modules. These programs are based on the neurodevelopmental hypothesis of schizophrenia. However, moderate improvement for patients who benefit from these therapies has been observed as described in Wykes et al. review (3). Next, neuropsychological models of schizophrenia are then presented. They highlight the critical role of the internally generated intentions in appropriate willful actions. The cognitive control mechanism deals with this ability. Interestingly, available cognitive remediation programs have not been influenced by these models. Hence, we propose another alternative to set up a specific cognitive remediation program for schizophrenia patients by targeting the cognitive control mechanism. We describe the PrACTice program that is in the process of being validated.

No MeSH data available.


Related in: MedlinePlus

Illustration from the inactive short-list, with the trial “To make pancakes” as objective. No strategy is suggested to make the decision task. The target required a “useful” answer.
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Figure 2: Illustration from the inactive short-list, with the trial “To make pancakes” as objective. No strategy is suggested to make the decision task. The target required a “useful” answer.

Mentions: Participants also experiment the inactive PrACTice short-list (see Figure 2) that is similar to the training lists but include only 10 trials, with objectives that will not be trained during the training sessions and which do not proposed the coaching strategies.


From Theory to PrACTice: A Cognitive Remediation Program Based on a Neuropsychological Model of Schizophrenia.

Fabre D, Vehier A, Chesnoy-Servanin G, Gouiller N, D'Amato T, Saoud M - Front Psychiatry (2015)

Illustration from the inactive short-list, with the trial “To make pancakes” as objective. No strategy is suggested to make the decision task. The target required a “useful” answer.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4664640&req=5

Figure 2: Illustration from the inactive short-list, with the trial “To make pancakes” as objective. No strategy is suggested to make the decision task. The target required a “useful” answer.
Mentions: Participants also experiment the inactive PrACTice short-list (see Figure 2) that is similar to the training lists but include only 10 trials, with objectives that will not be trained during the training sessions and which do not proposed the coaching strategies.

Bottom Line: However, moderate improvement for patients who benefit from these therapies has been observed as described in Wykes et al. review (3).Interestingly, available cognitive remediation programs have not been influenced by these models.We describe the PrACTice program that is in the process of being validated.

View Article: PubMed Central - PubMed

Affiliation: EA 4615, Centre Hospitalier le Vinatier, Université de Lyon , Bron , France.

ABSTRACT
Cognitive dysfunction is one of the hallmark deficits of schizophrenia. A wide range of studies illustrate how it is strongly interconnected to clinical presentation and daily life functioning [see Ref. (1, 2)]. Hence, cognition is an important treatment target in schizophrenia. To address the challenge of cognitive enhancement in schizophrenia, a large number of cognitive remediation programs have been developed and evaluated over the past several decades. First, an overview of these programs is presented highlighting their specificity to cognitive deficit in schizophrenia using an integrated method. In this case, cognitive training focuses on enhancing several elementary cognitive functions considered as a prerequisite to social skills or vocational training modules. These programs are based on the neurodevelopmental hypothesis of schizophrenia. However, moderate improvement for patients who benefit from these therapies has been observed as described in Wykes et al. review (3). Next, neuropsychological models of schizophrenia are then presented. They highlight the critical role of the internally generated intentions in appropriate willful actions. The cognitive control mechanism deals with this ability. Interestingly, available cognitive remediation programs have not been influenced by these models. Hence, we propose another alternative to set up a specific cognitive remediation program for schizophrenia patients by targeting the cognitive control mechanism. We describe the PrACTice program that is in the process of being validated.

No MeSH data available.


Related in: MedlinePlus