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Competition and Cooperation among Relational Memory Representations.

Schwarb H, Watson PD, Campbell K, Shander CL, Monti JM, Cooke GE, Wang JX, Kramer AF, Cohen NJ - PLoS ONE (2015)

Bottom Line: In this task, participants learned unique face-room associations in two distinct contexts (i.e., different colored buildings).Overall, performance was very accurate.This novel task provides a powerful tool for investigating both the unique and interacting contributions of these systems in support of relational memory.

View Article: PubMed Central - PubMed

Affiliation: University of Illinois, Beckman Institute for Advanced Science and Technology, Urbana, IL, United States of America.

ABSTRACT
Mnemonic processing engages multiple systems that cooperate and compete to support task performance. Exploring these systems' interaction requires memory tasks that produce rich data with multiple patterns of performance sensitive to different processing sub-components. Here we present a novel context-dependent relational memory paradigm designed to engage multiple learning and memory systems. In this task, participants learned unique face-room associations in two distinct contexts (i.e., different colored buildings). Faces occupied rooms as determined by an implicit gender-by-side rule structure (e.g., male faces on the left and female faces on the right) and all faces were seen in both contexts. In two experiments, we use behavioral and eye-tracking measures to investigate interactions among different memory representations in both younger and older adult populations; furthermore we link these representations to volumetric variations in hippocampus and ventromedial PFC among older adults. Overall, performance was very accurate. Successful face placement into a studied room systematically varied with hippocampal volume. Selecting the studied room in the wrong context was the most typical error. The proportion of these errors to correct responses positively correlated with ventromedial prefrontal volume. This novel task provides a powerful tool for investigating both the unique and interacting contributions of these systems in support of relational memory.

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Related in: MedlinePlus

Stimuli and design in the novel context-dependent relational memory test.(a) General display information and resulting regions of interest. (b) Study phase design and timing information. (c) Test phase design and timing information.
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pone.0143832.g001: Stimuli and design in the novel context-dependent relational memory test.(a) General display information and resulting regions of interest. (b) Study phase design and timing information. (c) Test phase design and timing information.

Mentions: In the current study, we explore the dynamics of competition and cooperation between sources of associative and contextual information as well as the memory systems supporting these processes. We introduce a novel memory paradigm (Fig 1) that provides participants with two sources of information: specific item-location associations, and general contextual rules. Participants studied a set of faces that appeared in specific rooms of multi-room building contexts that differ by color (one building is blue, one purple). Each face appeared in a unique room in each building (all faces were studied in both buildings). Face-room pairs were assigned using an underlying gender-by-side rule structure (e.g., female faces on the left in the blue building and on the right in the purple). At recall, participants were asked to place faces back in the room in which they were studied. Each face was tested in both building contexts.


Competition and Cooperation among Relational Memory Representations.

Schwarb H, Watson PD, Campbell K, Shander CL, Monti JM, Cooke GE, Wang JX, Kramer AF, Cohen NJ - PLoS ONE (2015)

Stimuli and design in the novel context-dependent relational memory test.(a) General display information and resulting regions of interest. (b) Study phase design and timing information. (c) Test phase design and timing information.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4664414&req=5

pone.0143832.g001: Stimuli and design in the novel context-dependent relational memory test.(a) General display information and resulting regions of interest. (b) Study phase design and timing information. (c) Test phase design and timing information.
Mentions: In the current study, we explore the dynamics of competition and cooperation between sources of associative and contextual information as well as the memory systems supporting these processes. We introduce a novel memory paradigm (Fig 1) that provides participants with two sources of information: specific item-location associations, and general contextual rules. Participants studied a set of faces that appeared in specific rooms of multi-room building contexts that differ by color (one building is blue, one purple). Each face appeared in a unique room in each building (all faces were studied in both buildings). Face-room pairs were assigned using an underlying gender-by-side rule structure (e.g., female faces on the left in the blue building and on the right in the purple). At recall, participants were asked to place faces back in the room in which they were studied. Each face was tested in both building contexts.

Bottom Line: In this task, participants learned unique face-room associations in two distinct contexts (i.e., different colored buildings).Overall, performance was very accurate.This novel task provides a powerful tool for investigating both the unique and interacting contributions of these systems in support of relational memory.

View Article: PubMed Central - PubMed

Affiliation: University of Illinois, Beckman Institute for Advanced Science and Technology, Urbana, IL, United States of America.

ABSTRACT
Mnemonic processing engages multiple systems that cooperate and compete to support task performance. Exploring these systems' interaction requires memory tasks that produce rich data with multiple patterns of performance sensitive to different processing sub-components. Here we present a novel context-dependent relational memory paradigm designed to engage multiple learning and memory systems. In this task, participants learned unique face-room associations in two distinct contexts (i.e., different colored buildings). Faces occupied rooms as determined by an implicit gender-by-side rule structure (e.g., male faces on the left and female faces on the right) and all faces were seen in both contexts. In two experiments, we use behavioral and eye-tracking measures to investigate interactions among different memory representations in both younger and older adult populations; furthermore we link these representations to volumetric variations in hippocampus and ventromedial PFC among older adults. Overall, performance was very accurate. Successful face placement into a studied room systematically varied with hippocampal volume. Selecting the studied room in the wrong context was the most typical error. The proportion of these errors to correct responses positively correlated with ventromedial prefrontal volume. This novel task provides a powerful tool for investigating both the unique and interacting contributions of these systems in support of relational memory.

Show MeSH
Related in: MedlinePlus