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Association of Habitual Patterns and Types of Physical Activity and Inactivity with MRI-Determined Total Volumes of Visceral and Subcutaneous Abdominal Adipose Tissue in a General White Population.

Fischer K, Rüttgers D, Müller HP, Jacobs G, Kassubek J, Lieb W, Nöthlings U - PLoS ONE (2015)

Bottom Line: There was also evidence of a threshold effect in some of these relationships.In conclusion, our results suggest that in white populations, habitual APAT rich in MPA might be insufficient to impact on accumulation of VAT or SAAT.APAT including ≥ 4.0-6.8 h/wk VPA, by contrast, are more strongly associated with lower VAT and SAAT.

View Article: PubMed Central - PubMed

Affiliation: Department of Nutrition and Food Sciences, University of Bonn, Bonn, Germany.

ABSTRACT
Population-based evidence for the role of habitual physical activity (PA) in the accumulation of visceral (VAT) and subcutaneous (SAAT) abdominal adipose tissue is limited. We investigated if usual patterns and types of self-reported PA and inactivity were associated with VAT and SAAT in a general white population. Total volumes of VAT and SAAT were quantified by magnetic resonance imaging in 583 men and women (61 ± 11.9 y; BMI 27.2 ± 4.4 kg/m2). Past-year PA and inactivity were self-reported by questionnaire. Exploratory activity patterns (APAT) were derived by principal components analysis. Cross-sectional associations between individual activities, total PA in terms of metabolic equivalents (PA MET), or overall APAT and either VAT or SAAT were analyzed by multivariable-adjusted robust or generalized linear regression models. Whereas vigorous-intensity PA (VPA) was negatively associated with both VAT and SAAT, associations between total PA MET, moderate-intensity PA (MPA), or inactivity and VAT and/or SAAT depended on sex. There was also evidence of a threshold effect in some of these relationships. Total PA MET was more strongly associated with VAT in men (B = -3.3 ± 1.4; P = 0.02) than women (B = -2.1 ± 1.1; P = 0.07), but was more strongly associated with SAAT in women (B = -5.7 ± 2.5; P = 0.05) than men (B = -1.7 ± 1.6; P = 0.3). Men (-1.52 dm3 or -1.89 dm3) and women (-1.15 dm3 or -2.61 dm3) in the highest (>6.8 h/wk VPA) or second (4.0-6.8 h/wk VPA) tertile of an APAT rich in VPA, had lower VAT and SAAT, respectively, than those in the lowest (<4.0 h/wk VPA) tertile (P ≤ 0.016; P trend ≤ 0.0005). They also had lower VAT and SAAT than those with APAT rich in MPA and/or inactivity only. In conclusion, our results suggest that in white populations, habitual APAT rich in MPA might be insufficient to impact on accumulation of VAT or SAAT. APAT including ≥ 4.0-6.8 h/wk VPA, by contrast, are more strongly associated with lower VAT and SAAT.

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Related in: MedlinePlus

Total volumes of VAT and SAAT for tertiles of physical activities and inactivities by sex (M/F) in Northern German adults.Data (n = 583 subjects) are LSM (± SE) of total volumes of (1) VAT or (2) SAAT from generalized linear models adjusted for age, total energy intake (kcal/d), smoking status (never, former, and current smoker), and height (final model 2) by tertile category and sex of individual physical activity variables (for exact data see also S2 Table). Multiple comparisons assessing statistical differences in LSM between tertiles were corrected by using the Tukey-Kramer procedure. Mean values without sharing a common superscript letter (a-b) were statistically different at P < 0.05. DIY, do-it-yourself; F, females; LSM, least-square mean; M, males; SAAT, subcutaneous abdominal adipose tissue; VAT, visceral abdominal adipose tissue.
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pone.0143925.g003: Total volumes of VAT and SAAT for tertiles of physical activities and inactivities by sex (M/F) in Northern German adults.Data (n = 583 subjects) are LSM (± SE) of total volumes of (1) VAT or (2) SAAT from generalized linear models adjusted for age, total energy intake (kcal/d), smoking status (never, former, and current smoker), and height (final model 2) by tertile category and sex of individual physical activity variables (for exact data see also S2 Table). Multiple comparisons assessing statistical differences in LSM between tertiles were corrected by using the Tukey-Kramer procedure. Mean values without sharing a common superscript letter (a-b) were statistically different at P < 0.05. DIY, do-it-yourself; F, females; LSM, least-square mean; M, males; SAAT, subcutaneous abdominal adipose tissue; VAT, visceral abdominal adipose tissue.

Mentions: In multivariable analysis adjusted for height (final model 2), stratified by sex and tertile category of individual activities (S2 Table and Fig 3) and considering B-Y FDR significance (P ≤ 0.016), there was a quadratic trend (Ptrend ≤ 0.002) between time spent on housework and VAT and SAAT among women, but not men. Compared to women spending <3 h/wk on housework, women had lower VAT and SAAT when 3–9 h/wk, but not when >9 h/wk, were spent on housework. As against subjects spending no time on DIY work, women, but not men, had higher SAAT when >1.5 h/wk, but not when ≤1.5 h/wk were spent on DIY work. For gardening, there was a linear trend for the association with SAAT among men (Ptrend = 0.001), but not women. Compared with men spending <0.4 h/wk gardening, men had higher SAAT when >2.8 h/wk, but not when 0.4–2.8 h/wk, were spent gardening. As against subjects spending <3.0 h/wk walking, women, but not men, had lower VAT and SAAT when ≥3.0 h/wk were spent walking. Regarding stair climbing, there was a linear trend for the association with VAT in men (Ptrend = 0.005), but not women. Compared to men climbing <1.0 stairs/d, men who climbed >4 stairs/d, but not those climbing 1–4 stairs/d, had lower VAT. Among both men and women, there was a linear trend for the association of cycling with VAT, and for men also with SAAT (Ptrend ≤ 0.004). Compared with subjects spending <0.4 h/wk cycling, men and women had lower VAT or SAAT when at least ≥0.4 h/wk were spent cycling. Similarly, there was a linear trend of lower VAT with increasing hours spent on sports among men and women, and for men also of lower SAAT (Ptrend ≤ 0.013). As against subjects spending <0.9 h/wk on sports, men and women spending >3.0 h/wk, but not those spending 0.9–3.0 h/wk, on sports had lower VAT, and males also lower SAAT. Compared with subjects spending <7.3 h/d sleeping, men had lower VAT when 7.3–8.2 h/d, but not when >8.2 h/d were spent, whereas women had higher VAT when ≥7.3 h/d were spent sleeping. Among both men and women, there was a linear trend (Ptrend ≤ 0.007) for the association between watching TV and VAT and SAAT. As against subjects spending <2.0 h/d watching TV, men and women had higher VAT or SAAT when >3.0 h/d, but not when 2.0–3.0 h/d, were spent watching TV.


Association of Habitual Patterns and Types of Physical Activity and Inactivity with MRI-Determined Total Volumes of Visceral and Subcutaneous Abdominal Adipose Tissue in a General White Population.

Fischer K, Rüttgers D, Müller HP, Jacobs G, Kassubek J, Lieb W, Nöthlings U - PLoS ONE (2015)

Total volumes of VAT and SAAT for tertiles of physical activities and inactivities by sex (M/F) in Northern German adults.Data (n = 583 subjects) are LSM (± SE) of total volumes of (1) VAT or (2) SAAT from generalized linear models adjusted for age, total energy intake (kcal/d), smoking status (never, former, and current smoker), and height (final model 2) by tertile category and sex of individual physical activity variables (for exact data see also S2 Table). Multiple comparisons assessing statistical differences in LSM between tertiles were corrected by using the Tukey-Kramer procedure. Mean values without sharing a common superscript letter (a-b) were statistically different at P < 0.05. DIY, do-it-yourself; F, females; LSM, least-square mean; M, males; SAAT, subcutaneous abdominal adipose tissue; VAT, visceral abdominal adipose tissue.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4664408&req=5

pone.0143925.g003: Total volumes of VAT and SAAT for tertiles of physical activities and inactivities by sex (M/F) in Northern German adults.Data (n = 583 subjects) are LSM (± SE) of total volumes of (1) VAT or (2) SAAT from generalized linear models adjusted for age, total energy intake (kcal/d), smoking status (never, former, and current smoker), and height (final model 2) by tertile category and sex of individual physical activity variables (for exact data see also S2 Table). Multiple comparisons assessing statistical differences in LSM between tertiles were corrected by using the Tukey-Kramer procedure. Mean values without sharing a common superscript letter (a-b) were statistically different at P < 0.05. DIY, do-it-yourself; F, females; LSM, least-square mean; M, males; SAAT, subcutaneous abdominal adipose tissue; VAT, visceral abdominal adipose tissue.
Mentions: In multivariable analysis adjusted for height (final model 2), stratified by sex and tertile category of individual activities (S2 Table and Fig 3) and considering B-Y FDR significance (P ≤ 0.016), there was a quadratic trend (Ptrend ≤ 0.002) between time spent on housework and VAT and SAAT among women, but not men. Compared to women spending <3 h/wk on housework, women had lower VAT and SAAT when 3–9 h/wk, but not when >9 h/wk, were spent on housework. As against subjects spending no time on DIY work, women, but not men, had higher SAAT when >1.5 h/wk, but not when ≤1.5 h/wk were spent on DIY work. For gardening, there was a linear trend for the association with SAAT among men (Ptrend = 0.001), but not women. Compared with men spending <0.4 h/wk gardening, men had higher SAAT when >2.8 h/wk, but not when 0.4–2.8 h/wk, were spent gardening. As against subjects spending <3.0 h/wk walking, women, but not men, had lower VAT and SAAT when ≥3.0 h/wk were spent walking. Regarding stair climbing, there was a linear trend for the association with VAT in men (Ptrend = 0.005), but not women. Compared to men climbing <1.0 stairs/d, men who climbed >4 stairs/d, but not those climbing 1–4 stairs/d, had lower VAT. Among both men and women, there was a linear trend for the association of cycling with VAT, and for men also with SAAT (Ptrend ≤ 0.004). Compared with subjects spending <0.4 h/wk cycling, men and women had lower VAT or SAAT when at least ≥0.4 h/wk were spent cycling. Similarly, there was a linear trend of lower VAT with increasing hours spent on sports among men and women, and for men also of lower SAAT (Ptrend ≤ 0.013). As against subjects spending <0.9 h/wk on sports, men and women spending >3.0 h/wk, but not those spending 0.9–3.0 h/wk, on sports had lower VAT, and males also lower SAAT. Compared with subjects spending <7.3 h/d sleeping, men had lower VAT when 7.3–8.2 h/d, but not when >8.2 h/d were spent, whereas women had higher VAT when ≥7.3 h/d were spent sleeping. Among both men and women, there was a linear trend (Ptrend ≤ 0.007) for the association between watching TV and VAT and SAAT. As against subjects spending <2.0 h/d watching TV, men and women had higher VAT or SAAT when >3.0 h/d, but not when 2.0–3.0 h/d, were spent watching TV.

Bottom Line: There was also evidence of a threshold effect in some of these relationships.In conclusion, our results suggest that in white populations, habitual APAT rich in MPA might be insufficient to impact on accumulation of VAT or SAAT.APAT including ≥ 4.0-6.8 h/wk VPA, by contrast, are more strongly associated with lower VAT and SAAT.

View Article: PubMed Central - PubMed

Affiliation: Department of Nutrition and Food Sciences, University of Bonn, Bonn, Germany.

ABSTRACT
Population-based evidence for the role of habitual physical activity (PA) in the accumulation of visceral (VAT) and subcutaneous (SAAT) abdominal adipose tissue is limited. We investigated if usual patterns and types of self-reported PA and inactivity were associated with VAT and SAAT in a general white population. Total volumes of VAT and SAAT were quantified by magnetic resonance imaging in 583 men and women (61 ± 11.9 y; BMI 27.2 ± 4.4 kg/m2). Past-year PA and inactivity were self-reported by questionnaire. Exploratory activity patterns (APAT) were derived by principal components analysis. Cross-sectional associations between individual activities, total PA in terms of metabolic equivalents (PA MET), or overall APAT and either VAT or SAAT were analyzed by multivariable-adjusted robust or generalized linear regression models. Whereas vigorous-intensity PA (VPA) was negatively associated with both VAT and SAAT, associations between total PA MET, moderate-intensity PA (MPA), or inactivity and VAT and/or SAAT depended on sex. There was also evidence of a threshold effect in some of these relationships. Total PA MET was more strongly associated with VAT in men (B = -3.3 ± 1.4; P = 0.02) than women (B = -2.1 ± 1.1; P = 0.07), but was more strongly associated with SAAT in women (B = -5.7 ± 2.5; P = 0.05) than men (B = -1.7 ± 1.6; P = 0.3). Men (-1.52 dm3 or -1.89 dm3) and women (-1.15 dm3 or -2.61 dm3) in the highest (>6.8 h/wk VPA) or second (4.0-6.8 h/wk VPA) tertile of an APAT rich in VPA, had lower VAT and SAAT, respectively, than those in the lowest (<4.0 h/wk VPA) tertile (P ≤ 0.016; P trend ≤ 0.0005). They also had lower VAT and SAAT than those with APAT rich in MPA and/or inactivity only. In conclusion, our results suggest that in white populations, habitual APAT rich in MPA might be insufficient to impact on accumulation of VAT or SAAT. APAT including ≥ 4.0-6.8 h/wk VPA, by contrast, are more strongly associated with lower VAT and SAAT.

Show MeSH
Related in: MedlinePlus