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A 35-year old woman with productive cough and breathlessness.

Kalai U, Hadda V, Madan K, Arava S, Ali F, Jain N, Mohan A - Lung India (2015 Nov-Dec)

Bottom Line: Radiograph and CT scan of the chest revealed right upper lobe consolidation.Flexible fibreoptic bronchoscopy revealed multiple nodules at opening of right upper lobe bronchus.This clinicopathological conference describes the details of differential diagnoses, difficulties in achieving the final diagnosis and management of such patient.

View Article: PubMed Central - PubMed

Affiliation: Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India.

ABSTRACT
A 35-year-old lady was seen in the outpatient clinic owing to fever, cough with mucopurulent expectoration, and breathlessness for the duration of 1 month. She had history of similar episodes treated with antibiotics four times during last 2 years. There was no history of recurrent sinusitis, diarrhea, and skin or soft tissue infection. She had no history of diabetes mellitus or steroid intake. She denied any history of facial trauma or dental infection in the past. There was no history of tuberculosis in her or in the family. Radiograph and CT scan of the chest revealed right upper lobe consolidation. Flexible fibreoptic bronchoscopy revealed multiple nodules at opening of right upper lobe bronchus. This clinicopathological conference describes the details of differential diagnoses, difficulties in achieving the final diagnosis and management of such patient.

No MeSH data available.


Related in: MedlinePlus

(a) Photomicrograph showing colonies of Actinomyces bacteria (b) High-power view at the periphery reveals thin filamentous bacterial colonies (arrow) (c) Fragment showing respiratory epithelium (d) Gram stain confirms the thin filamentous nature of the bacteria
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Figure 3: (a) Photomicrograph showing colonies of Actinomyces bacteria (b) High-power view at the periphery reveals thin filamentous bacterial colonies (arrow) (c) Fragment showing respiratory epithelium (d) Gram stain confirms the thin filamentous nature of the bacteria

Mentions: Firdaus Ali: The endobronchial biopsy from the growth showed the presence of abundant necrosis with inflammatory infiltrate and bacterial colonies of Actinomycosis [Figure 3]. Actinomyces stains in tissue with Gomori methenamine silver and the Brown and Brenn modification of the Gram stain. “Sulfur granules” that are seen as round or oval basophilic masses with a radiating arrangement of eosinophilic clubs on the surface are the pathological hallmark of the disease. These sometimes can be seen with a magnifying glass.[6]


A 35-year old woman with productive cough and breathlessness.

Kalai U, Hadda V, Madan K, Arava S, Ali F, Jain N, Mohan A - Lung India (2015 Nov-Dec)

(a) Photomicrograph showing colonies of Actinomyces bacteria (b) High-power view at the periphery reveals thin filamentous bacterial colonies (arrow) (c) Fragment showing respiratory epithelium (d) Gram stain confirms the thin filamentous nature of the bacteria
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4663880&req=5

Figure 3: (a) Photomicrograph showing colonies of Actinomyces bacteria (b) High-power view at the periphery reveals thin filamentous bacterial colonies (arrow) (c) Fragment showing respiratory epithelium (d) Gram stain confirms the thin filamentous nature of the bacteria
Mentions: Firdaus Ali: The endobronchial biopsy from the growth showed the presence of abundant necrosis with inflammatory infiltrate and bacterial colonies of Actinomycosis [Figure 3]. Actinomyces stains in tissue with Gomori methenamine silver and the Brown and Brenn modification of the Gram stain. “Sulfur granules” that are seen as round or oval basophilic masses with a radiating arrangement of eosinophilic clubs on the surface are the pathological hallmark of the disease. These sometimes can be seen with a magnifying glass.[6]

Bottom Line: Radiograph and CT scan of the chest revealed right upper lobe consolidation.Flexible fibreoptic bronchoscopy revealed multiple nodules at opening of right upper lobe bronchus.This clinicopathological conference describes the details of differential diagnoses, difficulties in achieving the final diagnosis and management of such patient.

View Article: PubMed Central - PubMed

Affiliation: Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India.

ABSTRACT
A 35-year-old lady was seen in the outpatient clinic owing to fever, cough with mucopurulent expectoration, and breathlessness for the duration of 1 month. She had history of similar episodes treated with antibiotics four times during last 2 years. There was no history of recurrent sinusitis, diarrhea, and skin or soft tissue infection. She had no history of diabetes mellitus or steroid intake. She denied any history of facial trauma or dental infection in the past. There was no history of tuberculosis in her or in the family. Radiograph and CT scan of the chest revealed right upper lobe consolidation. Flexible fibreoptic bronchoscopy revealed multiple nodules at opening of right upper lobe bronchus. This clinicopathological conference describes the details of differential diagnoses, difficulties in achieving the final diagnosis and management of such patient.

No MeSH data available.


Related in: MedlinePlus